Results 281 to 290 of about 282,175 (385)

A pathway toward clinical translation of hyperpolarized [1,4‐13C2,2,3‐d2]fumarate as an imaging biomarker for early cellular necrosis in vivo

open access: yesMagnetic Resonance in Medicine, Volume 94, Issue 3, Page 1202-1217, September 2025.
Abstract Purpose The detection of hyperpolarized carbon‐13 (HP 13C)‐fumarate conversion to 13C‐malate using 13C‐MRSI is a biomarker for early detection of cellular necrosis. Here, we describe the translation of HP 13C‐fumarate as a novel human imaging agent, including the evaluation of biocompatibility and scaling up of the hyperpolarization methods ...
Jonathan R. Birchall   +25 more
wiley   +1 more source

An innovative benefit‐of‐the‐doubt approach for health system effectiveness: a global case study on amenable mortality

open access: yesInternational Transactions in Operational Research, Volume 32, Issue 5, Page 2847-2877, September 2025.
Abstract Health system performance assessment (HSPA) is essential for health planning and to improve population health. One of the HSPA domains is related to effectiveness, which can be represented considering different dimensions. Composite indicators can be used to summarize complex constructs involving several indicators. One example of such efforts
Giovanna D'Inverno   +2 more
wiley   +1 more source

The Role of Myocardial Gap Junction in Ischemia-Reperfusion Injury in Senescent Rabbit Myocardium.

open access: bronze, 2001
Yasunari Nakai   +7 more
openalex   +2 more sources

Bioactive Compounds, Their Mechanisms of Action, and Cardioprotective Effects of Pomegranate (Punica granatum): A Comprehensive Review

open access: yeseFood, Volume 6, Issue 4, August 2025.
Pomegranate parts (arils, peel, and flower) contain antioxidants, polyphenols, and flavonoids. These bioactives reduce inflammation, improve endothelial function, and modulate lipids. Regular intake lowers blood pressure, LDL, and atherosclerotic plaque while increasing HDL.
Esha Saeed   +11 more
wiley   +1 more source

Reduction of myocardial reperfusion injury by aprotinin after regional ischemia and cardioplegic arrest [PDF]

open access: bronze, 2004
Tanveer Khan   +8 more
openalex   +1 more source

Innate Immune Response After Cardiac Arrest (INNATUS): A Study Protocol for an Observational Single‐Center Pilot Study

open access: yesActa Anaesthesiologica Scandinavica, Volume 69, Issue 7, August 2025.
ABSTRACT Background The treatment of cardiac arrest (CA) patients is often complicated by post‐cardiac arrest syndrome (PCAS), which involves a systemic inflammatory response. Increased levels of certain inflammatory markers (e.g., interleukin‐6 and procalcitonin) are associated with higher mortality and worse neurological outcomes.
Asser M. J. Seppä   +9 more
wiley   +1 more source

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