Results 291 to 300 of about 285,668 (333)
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Cellular mechanisms and pathways in myocardial reperfusion injury
Coronary Artery Disease, 2021Despite the progress of cardiovascular medicine, ischemia-reperfusion injury can contribute to increased mortality and prolonged hospitalization after myocardial infarction.
Ioannis Valikeserlis +2 more
semanticscholar +1 more source
Regulated cell death in myocardial ischemia–reperfusion injury
Trends in endocrinology and metabolism, 2023Myocardial ischemia-reperfusion (I/R) injury most commonly occurs in coronary artery disease when prompt reperfusion is used to salvage the ischemic myocardium. Cardiomyocyte death is a significant component of myocardial I/R injury and its mechanism was
Qi Xiang +4 more
semanticscholar +1 more source
The role of PI3K/AKT signaling pathway in myocardial ischemia-reperfusion injury.
International Immunopharmacology, 2023Myocardial ischemia has a high incidence and mortality rate, and reperfusion is currently the standard intervention. However, reperfusion may lead to further myocardial damage, known as myocardial ischemia/reperfusion injury (MIRI).
Rui Deng, Juan Zhou
semanticscholar +1 more source
Myocardial ischemia-reperfusion injury; Molecular mechanisms and prevention.
Microvascular Research, 2023Cardiovascular diseases are one of the leading causes of mortality in developed countries. Among cardiovascular disorders, myocardial infarction remains a life-threatening problem predisposing to the development and progression of ischemic heart failure.
Yang Liu +4 more
semanticscholar +1 more source
'Myocardial Ischemia-Reperfusion Injury and the Influence of Inflammation.
Trends in cardiovascular medicine, 2022Acute myocardial infarction is caused by a sudden coronary artery occlusion and leads to ischemia in the corresponding myocardial territory which generally results in myocardial necrosis.
M. Algoet +6 more
semanticscholar +1 more source
Bucillamine Prevents Myocardial Reperfusion Injury
Journal of Cardiovascular Pharmacology, 2001Injury during reperfusion can partially offset the benefit of relief of ischemia in myocardial infarctions rapidly treated with thrombolytic drugs or angioplasty. We assessed whether bucillamine (N-[2-mercapto-2-methylpropionyl]-L-cysteine) is potentially useful to treat myocardial reperfusion injury.
L D, Horwitz, N A, Sherman
openaire +2 more sources
Mechanisms of myocardial reperfusion injury
The Annals of Thoracic Surgery, 1999Reperfusion of the ischemic myocardium results in irreversible tissue injury and cell necrosis, leading to decreased cardiac performance. While early reperfusion of the heart is essential in preventing further tissue damage due to ischemia, reintroduction of blood flow can expedite the death of vulnerable, but still viable, myocardial tissue, by ...
J L, Park, B R, Lucchesi
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Myocardial postconditioning: reperfusion injury revisited
American Journal of Physiology-Heart and Circulatory Physiology, 2005coronary heart disease is the leading cause of death in the Western world and represents one of the major burdens on healthcare systems today. Targeting those strategies that limit the damage sustained as a result of a lethal ischemic insult has been a major goal for many years.
Andrew, Tsang +2 more
openaire +2 more sources
Critical Care Nursing Clinics of North America, 1990
A review of the mechanism of ischemic-reperfusion injury, proposed interventions to prevent injury, and future directions have been presented to enhance the practitioner's knowledge of this new, exciting concept in myocardial injury. There is increasing evidence in the literature that reperfusion injury may occur in other organ systems and is ...
openaire +2 more sources
A review of the mechanism of ischemic-reperfusion injury, proposed interventions to prevent injury, and future directions have been presented to enhance the practitioner's knowledge of this new, exciting concept in myocardial injury. There is increasing evidence in the literature that reperfusion injury may occur in other organ systems and is ...
openaire +2 more sources

