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The role of gut microbiota in myocardial ischemia-reperfusion injury [PDF]
Frontiers in Cardiovascular MedicineMyocardial ischemia-reperfusion injury denotes the pathological damage resulting from the restoration of blood flow and oxygen supply following acute coronary artery occlusion.
Xin Chen +9 more
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Myocardial Ischemia Reperfusion Injury [PDF]
Seminars in Cardiothoracic and Vascular Anesthesia, 2012 Myocardial ischemia reperfusion injury contributes to adverse cardiovascular outcomes after myocardial ischemia, cardiac surgery or circulatory arrest. Primarily, no blood flow to the heart causes an imbalance between oxygen demand and supply, named ischemia (from the Greek isch, restriction; and haema, blood), resulting in damage or dysfunction of ...
Stephanie Bonney +2 more
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Myocardial ischemia – reperfusion injury
Zaporožskij Medicinskij Žurnal, 2023 Aim. To summarize and broaden the idea about mechanisms of acute coronary insufficiency development and pathophysiological features of myocardial reperfusion injury.
S. V. Salo +3 more
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Evolving Therapies for Myocardial Ischemia/Reperfusion Injury
Journal of the American College of Cardiology, 2015 The damage inflicted on the myocardium during acute myocardial infarction is the result of 2 processes: ischemia and subsequent reperfusion (ischemia/reperfusion injury). During the last 3 decades, therapies to reduce ischemic injury (mainly reperfusion strategies) have been widely incorporated into clinical practice.
Borja Ibanez +2 more
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The role of the autophagy in myocardial ischemia/reperfusion injury
Biochimica Et Biophysica Acta - Molecular Basis of Disease, 2015 Autophagy is an intracellular process responsible for damaged or unnecessary protein and organelle degradation. In the heart, autophagy occurs at basal level and dysregulated autophagy is associated with a variety of cardiovascular diseases. Autophagy is enhanced in ischemia as well as in the reperfusion phase during cardiac ischemia reperfusion (I/R ...
Yabin Wang, Yundai Chen, Feng Cao
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Frontiers in Cardiovascular Medicine, 2021 Myocardial ischemia/reperfusion injury is a common clinical problem and can result in severe cardiac dysfunction. Previous studies have demonstrated the protection of electroacupuncture against myocardial ischemia/reperfusion injury. However, the role of
Nisha Wang +9 more
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Platelets in Myocardial Ischemia/Reperfusion Injury
Hämostaseologie, 2022 AbstractCoronary artery disease, including myocardial infarction (MI), remains a leading cause of global mortality. Rapid reperfusion therapy is key to the improvement of patient outcome but contributes substantially to the final cardiac damage. This phenomenon is called “ischemia/reperfusion injury (IRI).” The underlying mechanisms of IRI are complex ...
Schanze, Nancy +4 more
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Frontiers in Cardiovascular Medicine, 2022 Exploring effective methods to lessen myocardial ischemia-reperfusion injury still has positive significance. The adenosine A2a receptor (A2aR) has played a crucial part in cardiac ischemia-reperfusion injury. Previous studies revealed that the adenosine
Yun Xia +9 more
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Ubiquitin-specific protease 7 regulates myocardial ischemia/reperfusion injury by stabilizing Keap1
Cell Death Discovery, 2022 Myocardial ischemia/reperfusion (I/R) injury is a complex pathological process that is still not fully understood. The oxidative stress response has a critical role in the occurrence and progression of myocardial ischemia/reperfusion injury.
Qiong Xu +10 more
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Mediators of Inflammation, 2023 Objective. Ischemia-reperfusion injury often occurs in organ transplantation, coronary heart disease, ischemic heart disease, and other diseases, which greatly reduces clinical efficacy.
Jinwei Gao, Zheng Wang, Zhangzhang Ye
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