Results 21 to 30 of about 170,764 (299)
Biomedicine and Pharmacotherapy, 2023 Acute myocardial infarction remains the leading cause of death in humans. Timely restoration of blood perfusion to ischemic myocardium remains the most effective strategy in the treatment of acute myocardial infarction, which can significantly reduce ...
Tianqing Zhang, Yanfang Luo
exaly +2 more sources
Cell Metabolism, 2021 Myocardial ischemia-reperfusion (MIR) injury is a major cause of adverse outcomes of revascularization after myocardial infarction. To identify the fundamental regulator of reperfusion injury, we performed metabolomics profiling in plasma of individuals ...
Xiao-Jing Zhang, Dating Sun, Xu Cheng
exaly +2 more sources
The role of the autophagy in myocardial ischemia/reperfusion injury
Biochimica Et Biophysica Acta - Molecular Basis of Disease, 2015 Autophagy is an intracellular process responsible for damaged or unnecessary protein and organelle degradation. In the heart, autophagy occurs at basal level and dysregulated autophagy is associated with a variety of cardiovascular diseases. Autophagy is enhanced in ischemia as well as in the reperfusion phase during cardiac ischemia reperfusion (I/R ...
Yabin Wang
exaly +3 more sources
Frontiers in Cardiovascular Medicine, 2021 Myocardial ischemia/reperfusion injury is a common clinical problem and can result in severe cardiac dysfunction. Previous studies have demonstrated the protection of electroacupuncture against myocardial ischemia/reperfusion injury. However, the role of
Nisha Wang +9 more
doaj +1 more source
Platelets in Myocardial Ischemia/Reperfusion Injury
Hämostaseologie, 2022 AbstractCoronary artery disease, including myocardial infarction (MI), remains a leading cause of global mortality. Rapid reperfusion therapy is key to the improvement of patient outcome but contributes substantially to the final cardiac damage. This phenomenon is called “ischemia/reperfusion injury (IRI).” The underlying mechanisms of IRI are complex ...
Schanze, Nancy +4 more
openaire +3 more sources
Frontiers in Cardiovascular Medicine, 2022 Exploring effective methods to lessen myocardial ischemia-reperfusion injury still has positive significance. The adenosine A2a receptor (A2aR) has played a crucial part in cardiac ischemia-reperfusion injury. Previous studies revealed that the adenosine
Yun Xia +9 more
doaj +1 more source
Mediators of Inflammation, 2023 Objective. Ischemia-reperfusion injury often occurs in organ transplantation, coronary heart disease, ischemic heart disease, and other diseases, which greatly reduces clinical efficacy.
Jinwei Gao, Zheng Wang, Zhangzhang Ye
doaj +1 more source
Bioactive Materials, 2022 Interventional coronary reperfusion strategies are widely adopted to treat acute myocardial infarction, but morbidity and mortality of acute myocardial infarction are still high.
Tianjiao Zhao +6 more
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Circulation, 2023 Background: Myocardial ischemia-reperfusion (I/R) injury causes cardiac dysfunction to myocardial cell loss and fibrosis. Prevention of cell death is important to protect cardiac function after I/R injury.
Wenbin Cai +9 more
semanticscholar +1 more source
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2023 Background Identifying new therapeutic targets for preventing the myocardial ischemia–reperfusion injury would have profound implications in cardiovascular medicine.
Pavel Zhabyeyev +8 more
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