Results 31 to 40 of about 170,764 (299)

Abnormalities of glucose and lipid metabolism in myocardial ischemia-reperfusion injury.

open access: yesBiomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2023
Myocardial ischemia-reperfusion injury is a common condition in cardiovascular diseases, and the mechanism of its occurrence involves multiple complex metabolic pathways and signaling pathways.
Hao Tian   +3 more
semanticscholar   +1 more source

Deubiquitinase OTUD5 as a Novel Protector against 4‐HNE‐Triggered Ferroptosis in Myocardial Ischemia/Reperfusion Injury

open access: yesAdvancement of science, 2023
Despite the development of advanced technologies for interventional coronary reperfusion after myocardial infarction, a substantial number of patients experience high mortality due to myocardial ischemia‐reperfusion (MI/R) injury.
Lulu Liu   +19 more
semanticscholar   +1 more source

Opportunities and challenges of pain-related myocardial ischemia-reperfusion injury

open access: yesFrontiers in Physiology, 2022
Pain is one of the most serious problems plaguing human health today. Pain is not an independent pathophysiological condition and is associated with a high impact on elevated disability and organ dysfunction.
Wenhua Jiang   +5 more
doaj   +1 more source

Dapagliflozin alleviates myocardial ischemia/reperfusion injury by reducing ferroptosis via MAPK signaling inhibition

open access: yesFrontiers in Pharmacology, 2023
Reperfusion is essential for ischemic myocardium but paradoxically leads to myocardial damage that worsens cardiac functions. Ferroptosis often occurs in cardiomyocytes during ischemia/reperfusion (I/R).
Weixia Chen   +7 more
semanticscholar   +1 more source

Propofol has delayed myocardial protective effects after a regional ischemia/reperfusion injury in an in vivo rat heart model [PDF]

open access: yesKorean Journal of Anesthesiology, 2010
BackgroundIt is well known that propofol protects myocardium against myocardial ischemia/reperfusion injury in the rat heart model. The aim of this study was to investigate whether propofol provides a protective effect against a regional myocardial ...
Il Woo Shin   +7 more
doaj   +1 more source

Ubiquitin-specific protease 11 Aggravates Ischemia-reperfusion-induced Cardiomyocyte Pyroptosis and Injury by Promoting TRAF3 Deubiquitination

open access: yesBalkan Medical Journal, 2023
Background: In myocardial ischemia-reperfusion injury, myocardial damage is aggravated when blood perfusion is restored in myocardial infarction. Ubiquitin-specific protease 11 (USP11), a deubiquitinating enzyme, could remove the ubiquitination of ...
Yunfei Zhang   +4 more
doaj   +1 more source

Myocardial ischemia/reperfusion injury: Mechanisms of injury and implications for management (Review)

open access: yesExperimental and Therapeutic Medicine, 2022
Myocardial infarction is one of the primary causes of mortality in patients with coronary heart disease worldwide. Early treatment of acute myocardial infarction restores blood supply of ischemic myocardium and decreases the mortality risk. However, when
Jianfeng He   +6 more
semanticscholar   +1 more source

Ilexsaponin A attenuates ischemia-reperfusion-induced myocardial injury through anti-apoptotic pathway. [PDF]

open access: yesPLoS ONE, 2017
The protective effects of ilexsaponin A on ischemia-reperfusion-induced myocardial injury were investigated. Myocardial ischemia/reperfusion model was established in male Sprague-Dawley rats. Myocardial injury was evaluated by TTC staining and myocardial
Shuang-Wei Zhang   +6 more
doaj   +1 more source

The role of glycogen synthase kinase 3 beta in brain injury induced by myocardial ischemia/reperfusion injury in a rat model of diabetes mellitus

open access: yesNeural Regeneration Research, 2017
Myocardial ischemia/reperfusion injury can lead to severe brain injury. Glycogen synthase kinase 3 beta is known to be involved in myo-cardial ischemia/reperfusion injury and diabetes mellitus. However, the precise role of glycogen synthase kinase 3 beta
Bo Zhao   +7 more
doaj   +1 more source

Inflammation in Myocardial Ischemia/Reperfusion Injury: Underlying Mechanisms and Therapeutic Potential

open access: yesAntioxidants, 2023
Acute myocardial infarction (MI) occurs when blood flow to the myocardium is restricted, leading to cardiac damage and massive loss of viable cardiomyocytes.
J. Francisco, D. D. Del Re
semanticscholar   +1 more source

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