Results 41 to 50 of about 170,764 (299)
Myocardial protective effect by ulinastatin via an anti-inflammatory response after regional ischemia/reperfusion injury in an in vivo rat heart model [PDF]
Korean Journal of Anesthesiology, 2011 BackgroundUlinastatin has anti-inflammatory properties and protects organs from ischemia/reperfusion-induced injury. The aim of this study was to investigate whether ulinastatin provides a protective effect on a regional myocardial ischemia/reperfusion ...
Il-Woo Shin +7 more
doaj +1 more source
Acta Cirúrgica Brasileira, 2022 Purpose: The present study explored the role and mechanism involved in aprepitant-induced cardioprotective effects in rat model of ischemia-reperfusion injury.
Mei Qian, Yang Liu
doaj +1 more source
Status of myocardial antioxidants in ischemia–reperfusion injury [PDF]
Cardiovascular Research, 2000 Myocardial ischemia-reperfusion represents a clinically relevant problem associated with thrombolysis, angioplasty and coronary bypass surgery. Injury of myocardium due to ischemia-reperfusion includes cardiac contractile dysfunction, arrhythmias as well as irreversible myocyte damage.
N S, Dhalla +3 more
openaire +2 more sources
Novel roles of κ-opioid receptor in myocardial ischemia-reperfusion injury [PDF]
PeerJAcute heart attack is the primary cause of cardiovascular-related death worldwide. A common treatment is reperfusion of ischemic tissue, which can cause irreversible damage to the myocardium.
Wen Zhang +4 more
doaj +2 more sources
Curcumin attenuates myocardial ischemia-reperfusion injury
Oncotarget, 2017 Cardiovascular diseases (CVDs) are at a badly high-risk of morbidity and mortality in the world.Our study was attempted to investigate the cardioprotective role of curcumin. Hearts injury was assessed in isolated hearts and the rats of coronary artery ligated.The inhibition of pro-inflammatory cytokines was observed by curcumin in coronary artery ...
Liu, Kun +8 more
openaire +3 more sources
Resveratrol Protects against Myocardial Ischemia-Reperfusion Injury via Attenuating Ferroptosis.
Gene, 2021 Resveratrol (Res) is a polyphenol with a variety of biological activities. However, whether Res can prevent myocardial ischemia-reperfusion (I/R) injury is not yet known.
Ting Li +4 more
semanticscholar +1 more source
Advancement of science, 2022 Acute myocardial infarction (MI) is the leading cause of death worldwide. Exogenous delivery of nitric oxide (NO) to the infarcted myocardium has proven to be an effective strategy for treating MI due to the multiple physiological functions of NO ...
Tian Hao +8 more
semanticscholar +1 more source
Platelet Contributions to Myocardial Ischemia/Reperfusion Injury [PDF]
Frontiers in Immunology, 2019 Obstruction of a coronary artery causes ischemia of heart tissue leading to myocardial infarction. Prolonged oxygen deficiency provokes tissue necrosis, which can result in heart failure and death of the patient. Therefore, restoration of coronary blood flow (reperfusion of the ischemic area) by re-canalizing the affected vessel is essential for a ...
Schanze, Nancy +2 more
openaire +4 more sources
Phosphomimetic modulation of eNOS improves myocardial reperfusion and mimics cardiac postconditioning in mice. [PDF]
PLoS ONE, 2014 Myocardial infarction resulting from ischemia-reperfusion injury can be reduced by cardiac postconditioning, in which blood flow is restored intermittently prior to full reperfusion.
Terrence Pong +4 more
doaj +1 more source
Sphingolipid therapy in myocardial ischemia–reperfusion injury [PDF]
Biochimica et Biophysica Acta (BBA) - General Subjects, 2008 Sphingolipids are known to play a significant physiological role in cell growth, cell differentiation, and critical signal transduction pathways. Recent studies have demonstrated a significant role of sphingolipids and their metabolites in the pathogenesis of myocardial ischemia-reperfusion injury.
Susheel, Gundewar, David J, Lefer
openaire +2 more sources