Results 301 to 310 of about 282,175 (385)

Specialized Pro-Resolving Mediators as Emerging Players in Cardioprotection: From Inflammation Resolution to Therapeutic Potential. [PDF]

Acta Physiol (Oxf)
De Bartolo A, Romeo N, Angelone T, Rocca C.   +3 more
europepmc   +1 more source

Calcium Antagonist Clevidipine Reduces Myocardial Reperfusion Injury by a Mechanism Related to Bradykinin and Nitric Oxide

, 2002
Andrey Gourine, John Pernow, Dmitry M. Poputnikov, Per‐Ove Sjöquist   +3 more
openalex   +1 more source

Salvianolic Acid B Attenuates Ferroptosis in Acute Kidney Injury by Targeting PRDX5

The FASEB Journal, Volume 39, Issue 14, 31 July 2025.
Mechanistic diagram of SAB‐mediated alleviation of AKI through the regulation of PRDX5‐mediated ferroptosis in renal tubular epithelial cells. SAB alleviates cisplatin‐ and FA‐induced AKI by inhibiting ferroptosis via PRDX5‐mediated upregulation of SLC7A11, GPX4, and FSP1.
Yan Tao, Shengjun Fu, Jianzhong Lu, Beitang Fu, Shanhui Liu, Lanlan Li   +5 more
wiley   +1 more source

Nuclear Receptor ERRγ Protects Against Cardiac Ischemic Injury by Suppressing GBP5‐Mediated Myocardial Inflammation

The FASEB Journal, Volume 39, Issue 14, 31 July 2025.
Cardiomyocyte‐specific overexpression of ERRγ after myocardial infarction improves cardiac function by suppressing the expression of its pro‐inflammatory downstream target GBP5, thereby inhibiting inflammasome assembly, alleviating myocardial inflammation, and pyroptosis.
Junhao Qiu, Qianji Che, Yichao Zhang, Mu Chen, Zhixing Wei, Yangjinming Bai, Tingting Zhao, Ji Yan, Zhengyang Wu, Zhentao Fei, Yuepeng Wang, Qian Wang, Yi‐Gang Li   +12 more
wiley   +1 more source

Shifting landscapes: dynamic changes from pro- to anti-inflammatory leukocyte phenotype in myocardial ischemia/reperfusion injury. [PDF]

Front Cardiovasc Med
Kröning P, Mauler M, Schanze N, Naber K, Stallmann D, Duerschmied D, Westermann D, Gauchel N.   +7 more
europepmc   +1 more source

Mitochondrial Calcium Uniporter‐Mediated Regulation of the SIRT3/GSK3β/β‐Catenin Signaling Pathway in Vascular Remodeling

The FASEB Journal, Volume 39, Issue 13, 15 July 2025.
In HU and hypertensive rats, MCU expression in cerebral arteries is reduced. This reduction impairs cellular Ca2+ buffering and promotes mitochondrial oxidative stress. The stress response initiates the downstream degradation of SIRT3, which subsequently inhibits the activity of GSK3β via acetylation and promotes the nuclear translocation of β‐catenin,
Min Jiang, Lejian Lin, Shuai Yue, Shujin Shi, Haojie Yan, Hui Yi, Fan Han, Shuai Xu, Junjie Su, Ran Zhang   +9 more
wiley   +1 more source

MTX2 facilitates PKM2 tetramerization to promote cardiac glucose metabolism and protects the heart against ischemia/reperfusion injury. [PDF]

Theranostics
Li Y, Li Y, Li Y, Jiang Y, Wang M, Wang M, Liu J, Ma M, Zhai X, Yi L, Chen T, Xiong Z, Chen Y.   +12 more
europepmc   +1 more source

Protein‐Like Polymers Targeting Keap1/Nrf2 as Therapeutics for Myocardial Infarction

Advanced Materials, Volume 37, Issue 27, July 10, 2025.
We describe a Keap1 targeting protein‐like polymer (PLP) which activates Nrf2, an important cytoprotective transcription factor for relieving myocardial infarction‐induced oxidative stress. This PLP increases cell survival in vitro in multiple relevant cardiac cell types and elicits pro‐reparative responses, improving cardiac function in a preclinical ...
Joshua M. Mesfin, Kendal P. Carrow, Alexander Chen, Madeline P. Hopps, JoJo J. Holm, Quincy P. Lyons, Michael B. Nguyen, Jervaughn D. Hunter, Assa Magassa, Elyse G. Wong, Kate Reimold, Sriya N. Paleti, Emily Gardner, Matthew P. Thompson, Colin G. Luo, Xiaoyu Zhang, Karen L. Christman, Nathan C. Gianneschi   +17 more
wiley   +1 more source

Retraction: USP22 protects against myocardial ischemia-reperfusion injury via the SIRT1-p53/SLC7A11-dependent inhibition of ferroptosis-induced cardiomyocyte death. [PDF]

Front Physiol
Frontiers Editorial Office.
europepmc   +1 more source

Loss of Intracellular Dystrophin-A Potential Mechanism for Myocardial Reperfusion Injury-

, 2003
Shiori Kyoi, Hajime Otani, Tomohiko Sumida, Takayuki Okada, Motohiko Osako, Hiroji Imamura, Hiroshi Kamihata, Hiroaki Matsubara, Toshiji Iwasaka   +8 more
openalex   +2 more sources