Results 151 to 160 of about 136,887 (323)
Background Myocarditis is a major public health, social, and economic issue. Currently, few studies have provided comprehensive analyses of the global burden of myocarditis based on GBD (Global Burden Disease) 2021. We therefore analyzed long-term trends
Jiahui Li +5 more
doaj +1 more source
Incidents of sudden death during restraint of agitated individuals in Sweden between 1992 and 2024
Abstract Restraint‐related sudden deaths in agitated individuals raise complex questions at the intersection of medicine and law. Hyperactive delirium with extreme agitation as well as positional asphyxia due to restraint have been proposed to account for these deaths. However, the exact physiological mechanisms responsible and to what extent restraint
Alexander Tyr +4 more
wiley +1 more source
Interpretation of JCS 2023 Guideline on the Diagnosis and Treatment of Myocarditis
JCS 2023 Guideline on the Diagnosis and Treatment of Myocarditis offers a new perspective on the definition, classification, epidemiology, pathophysiology, diagnosis, diagnostic, treatment and management of myocarditis.
ZHANG Song +3 more
doaj +1 more source
Inflammatory Cytokines as Early Predictors of Weaning Failure From Extracorporeal Life Support
Levels of IL‐8 and IL‐6 and their dynamics are reliable early predictors of ECLS weaning failure. ABSTRACT Background Weaning from extracorporeal life support (ECLS) in patients with refractory shock still remains a complex decision. Despite considerable advances in ECLS management, reliable biomarkers to predict weaning success are still not available.
Kostiantyn Kozakov +11 more
wiley +1 more source
Myocarditis is an inflammation of the heart muscle. The most common cause of myocarditis is viral infections. clinical presentation of acute myocarditis is highly variable and varies from asymptomatic to fulminant heart failure or sudden death. Fulminant
Behnam Shakerian +1 more
doaj +1 more source
Treatment options for immune‐related adverse events associated with immune checkpoint inhibitors
Abstract The immunotherapy revolution with the use of immune checkpoint inhibitors (ICIs) started with the clinical use of the first ICI, ipilimumab, in 2011. Since then, the field of ICI therapy has rapidly expanded — with the FDA approval of 10 different ICI drugs so far and their incorporation into the therapeutic regimens of a range of malignancies.
Yu Hua Chen +3 more
wiley +1 more source
Giant cell myocarditis associated with lymphoma. [PDF]
Timothy R. Helliwell, Robert H. Edwards
openalex +1 more source
Background and Purpose Whereas the effects of Trypanosoma cruzi (T. cruzi) infection are well‐characterised in the heart, its impact on the vasculature has received little attention. In this study, we investigated the effects of acute and chronic T. cruzi infection on vascular responsiveness and the underlying mechanisms.
Thales M. H. Dourado +6 more
wiley +1 more source
Sex differences in mitochondrial gene expression during viral myocarditis
Background Myocarditis is an inflammation of the heart muscle most often caused by viral infections. Sex differences in the immune response during myocarditis have been well described but upstream mechanisms in the heart that might influence sex ...
Damian N. Di Florio +26 more
doaj +1 more source
The global Phase 3 IMpower010 study (NCT02486718) evaluated atezolizumab versus best supportive care (BSC) after complete resection and adjuvant platinum‐based chemotherapy in patients with stage IB–IIIA non‐small cell lung cancer (NSCLC). Here, we report updated efficacy and safety results from the disease‐free survival (DFS) final and overall ...
Morihito Okada +9 more
wiley +1 more source

