Results 151 to 160 of about 130,790 (247)

Integrated risk stratification for ICI-associated myocarditis: a baseline hematological profile and a combined ECG and enzymatic signature at onset. [PDF]

Front Immunol
Zheng Z, Dai C, Wu Q, Xie J, Gao M, Li X.   +5 more
europepmc   +1 more source

The role of extracellular vesicles in cell–cell crosstalk in cardiotoxicity

The Journal of Physiology, EarlyView.
Abstract figure legend Administration of a pharmacological agent can result in off‐target cardiotoxicity which can be driven by cell–cell crosstalk between healthy and dysfunctional cardiac cells. Extracellular vesicles (EVs) are lipid bilayer structures that can move biological cargo between cells, facilitating cell–cell crosstalk.
Gabriella Bachynskyj‐Bilas, Debbie J. Otto, Daniel Stratton, Katja Rietdorf, Daniel M. Johnson, Calum J. McMullen   +5 more
wiley   +1 more source

Intercalated disk structure, tissue heterogeneity and ion channel distribution modulate conduction and local calcium influx

The Journal of Physiology, EarlyView.
Abstract figure legend A, three‐dimensional representation of cardiac intercalated disk, reduced to a 100‐partition, computationally efficient network representation. B, ion dynamics within intercalated disk extracellular cleft space. C, rapid pacing leads to localized conduction block in tissue with regions of perturbed intercalated disk (ID ...
Nicolae Moise, Heather L. Struckman, James W. Smyth, Gregory S. Hoeker, Steven Poelzing, Rengasayee Veeraraghavan, Seth H. Weinberg   +6 more
wiley   +1 more source

Expanding Precompetitive Multisector Collaborations to Advance Drug Development and Pharmacogenomics. [PDF]

, 2020
Do, Thao P, Giacomini, Kathleen M, Huang, Shiew-Mei, Krauss, Ronald M, Kusuhara, Hiroyuki, Sugiyama, Yuichi, Unadkat, Jashvant D, Yee, Sook Wah   +7 more
core   +2 more sources

Clinical Characteristics and Risk Factors of Immune Checkpoint Inhibitor-Related Myocarditis: A Real World Observational Study. [PDF]

Clin Cardiol
Zhan M, Long Q, Liu R, Huang L, Wu B, Xu T, He J.   +6 more
europepmc   +1 more source

Impact of Rapid Exome Sequencing on Pediatric Patients With Cardiomyopathy and Acute Heart Failure

American Journal of Medical Genetics Part A, Volume 200, Issue 6, Page 1222-1230, June 2026.
ABSTRACT Few studies describe the impact of rapid exome sequencing (ES) on pediatric cardiomyopathy in urgent clinical settings. Here, we retrospectively report the impact of rapid singleton ES in pediatric patients presented with acute heart failure and isolated cardiomyopathy or myocarditis, between 2021 and 2023 at a single tertiary care center.
Tameemi Abdalla Moady, Tova Hershkovitz, Clair Habib, Ori Attias, Amir Hadash, Galit Tal, Asaad Khoury, Josef Ben‐Ari, Danny Eytan, Tamar Paperna, Karin Weiss   +10 more
wiley   +1 more source

Global, regional and national burden of myocarditis in adolescents and young adults, 1990-2021: systematic analysis of the global burden of disease study 2021. [PDF]

Front Cardiovasc Med
Zhao L, Lou Y, Gao Q.
europepmc   +1 more source

Stacked Ensemble Model With Explainable AI for Early Detection of Heart Disease

Analytical Science Advances, Volume 7, Issue 1, June 2026.
ABSTRACT Heart disease (HD) is still one of the most common causes of death around the world. Early detection is very important, but it is often hard to do because the symptoms are not specific and the models are not very clear. We propose a two‐layer stacked ensemble that combines four base learners—Support Vector Machine, K‐Nearest Neighbors, Naïve ...
Nazmun Nahar, Sanjatul Hasan Siam, Joy Bhowmik, Ayesha Nasrin Ripa, Md. Hasan Imam, Haw Jiunn Woo, Hamid Osman, Mayeen Uddin Khandaker, Shams Forruque Ahmed   +8 more
wiley   +1 more source

CARDIAC Score: A Framework for a Clinical Tool to Screen and Risk Stratify Pediatric Myocarditis, and Call for Collaboration to Evaluate Use. [PDF]

Cureus
Gould LA.
europepmc   +1 more source

A Case Series of Sudden Death in Children Aged 12 Months to 4 Years From LPIN1 Deficiency and PPA2 Deficiency in Queensland

Journal of Paediatrics and Child Health, EarlyView.
Sophie Manoy, Sally Smith, Marita Smith, Catherine Atthow, Janette Spicer, Matthew Lynch, Michelle Lipke, Julie A. McEniery, David Coman, Anita Inwood, Jim McGill, Carolyn Bursle   +11 more
wiley   +1 more source