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Viral myocarditis is associated with the development of dilated cardiomyopathy (DCM), left ventricular dysfunction, and heart failure. This review addresses the mechanisms of viral myocarditis and its treatment.
Ying C.
europepmc +6 more sources
The term myocarditis describes inflammatory disorders of the heart muscle of varied infectious and non-infectious origins. It can be caused by any kind of infection, drugs, toxic substances, or be associated with autoimmune conditions.
Uwe Kühl, Heinz-Peter Schultheiss
doaj +4 more sources
The protective effects of ivabradine in preventing progression from viral myocarditis to dilated cardiomyopathy [PDF]
To study the beneficial effects of ivabradine in dilated cardiomyopathy mice, which evolved from coxsackievirus B3-induced chronic viral myocarditis. Four-to-five-week-old male balb/c mice were inoculated intraperitoneally with coxsackievirus B3 (Strain ...
Li Yue-Chun +8 more
doaj +3 more sources
Viral myocarditis exhibits different clinical phenotypes depending on the age of the patient. In pediatric patients, viral myocarditis can present as acute heart failure and cardiogenic shock, and in older patients, it often presents as chronic, slowly progressive heart failure and dilated cardiomyopathy. The severity of viral myocarditis is determined
Peter P. Liu, M. Anne Opavsky
+8 more sources
Immune mechanisms of group B coxsackievirus induced viral myocarditis
Viral myocarditis is known to be a primary cause of dilated cardiomyopathy (DCM) that can lead to heart failure and sudden cardiac death and is invariably caused by myocardial viral infection following active inflammatory destruction of the myocardium ...
Yue Zhang +4 more
doaj +1 more source
Viral myocarditis is inflammation of the myocardium secondary to viral infection. The clinical presentation of viral myocarditis is very heterogeneous and can range from nonspecific symptoms of malaise and fatigue in subclinical disease to a more florid ...
Adedayo Adeboye +4 more
doaj +1 more source
In recent years, more young patients are being admitted to hospitals with the diagnosis of heart failure secondary to myocarditis; many of these patients will progress to needing a heart transplant. Research shows that heart failure is increasing in prevalence and incidence and is expected to have 46% increases in prevalence by 2030, with hypertension,
Oksana, Narovlyanskaya +1 more
openaire +3 more sources
Mechanisms and Therapeutic Strategies of Viral Myocarditis Targeting Autophagy
Viral myocarditis is caused by infection with viruses or bacteria, including coxsackievirus B3 (CVB3), and is characterized by acute or chronic inflammatory responses in the heart.
Kun Yu +11 more
doaj +1 more source
Background: The influence of different viral infections in patients with myocarditis is unknown. Myocarditis is an inflammatory disease of heart muscle that is commonly caused by viruses.
Chun Shing Kwok +4 more
doaj +1 more source
Immune checkpoint inhibitor (ICI) and coronavirus disease 2019 (COVID-19) vaccine-induced myocarditis possibly share common mechanisms secondary to overactivation of the immune system.
Lior Zornitzki +11 more
doaj +1 more source

