Decoding Undesirable Inflammatory Responses of Nucleic Acid‐Delivering Lipid Nanoparticles
Lipid nanoparticles (LNPs) enable efficient nucleic acid delivery, but their immunogenicity is a double‐edged sword. This review explores LNP‐driven innate and adaptive immunity, covering lipid components, endosomal escape, and nucleic acid sensing.
Ruimin Hu +6 more
wiley +1 more source
Spectral computed tomography as a novel diagnostic tool for mushroom poisoning-induced myocarditis: a case report. [PDF]
Yang H, Ruan J, Chen S, Su M.
europepmc +1 more source
ABSTRACT The intramuscular fat (IMF) content is an important indicator of meat quality, affecting the sensory properties of meat. IMF is a complex trait with polygenic nature. This research aimed to identify differentially expressed (DE) genes and key transcription factors (TFs) associated with IMF deposition in the liver of two rabbit lines ...
Jesús Valdés‐Hernández +4 more
wiley +1 more source
A case report of nonrheumatic myocarditis following group G streptococcus pharyngitis. [PDF]
Perkins SJ +5 more
europepmc +1 more source
Impact of Rapid Exome Sequencing on Pediatric Patients With Cardiomyopathy and Acute Heart Failure
ABSTRACT Few studies describe the impact of rapid exome sequencing (ES) on pediatric cardiomyopathy in urgent clinical settings. Here, we retrospectively report the impact of rapid singleton ES in pediatric patients presented with acute heart failure and isolated cardiomyopathy or myocarditis, between 2021 and 2023 at a single tertiary care center.
Tameemi Abdalla Moady +10 more
wiley +1 more source
Risk factors for sudden cardiac death or sudden unexplained death in patients treated with clozapine: systematic review. [PDF]
Easwar T +5 more
europepmc +1 more source
Stacked Ensemble Model With Explainable AI for Early Detection of Heart Disease
ABSTRACT Heart disease (HD) is still one of the most common causes of death around the world. Early detection is very important, but it is often hard to do because the symptoms are not specific and the models are not very clear. We propose a two‐layer stacked ensemble that combines four base learners—Support Vector Machine, K‐Nearest Neighbors, Naïve ...
Nazmun Nahar +8 more
wiley +1 more source
Imaging signatures of eosinophilic granulomatosis with polyangiitis-related myocarditis: A case report. [PDF]
Lamassab NEH +4 more
europepmc +1 more source
Interlukin‐5 (IL‐5) plays a crucial role in the pathogenesis of eosinophilic granulomatosis with polyangiitis (EGPA) by promoting eosinophil differentiation, activation, and survival. We present here a typical case of EGPA in which treatment with IL‐5 pathway inhibitors is prescribed, showing to be beneficial for the patient.
Alvise Berti, Christian Pagnoux
wiley +1 more source
Targeting Autoimmune Myocarditis with Lemon Balm Extract: In Vivo Molecular Approach. [PDF]
Lazarevic N +9 more
europepmc +1 more source

