Results 211 to 220 of about 109,922 (297)

Sphingosine‐1‐Phosphate Attenuates LPS‐Induced Inflammatory Cardiac Injury in Association With RASGRP1–S100A9–NLRP3 Signaling

open access: yesDrug Development Research, Volume 87, Issue 7, November 2026.
ABSTRACT Lipopolysaccharide (LPS) induces endotoxemia‐associated inflammatory cardiac injury rather than classical viral or autoimmune myocarditis. Sphingosine‐1‐phosphate (S1P) regulates cardiovascular and immune responses, predominantly through S1P receptors, but whether it also modulates macrophage‐associated inflammatory signaling during LPS ...
Chaofu Yue   +15 more
wiley   +1 more source

Dietary Interventions May Mitigate Health Risks of Per‐ and Polyfluoroalkyl Substances (PFAS) Exposure Through Modulation of the Gut Microbiota: A Review

open access: yesFood Frontiers, Volume 7, Issue 6, November 2026.
Dietary interventions, including probiotics, prebiotics, and synbiotics, may modulate gut microbiota to regulate PFAS accumulation and elimination. Specific microbial taxa facilitate PFAS removal through adsorption and bioaccumulation, potentially reducing internal PFAS burden and mitigating PFAS‐related health risks.
Jiahui Xia   +9 more
wiley   +1 more source

Supplementing With the Vitamin A Metabolite Retinoic Acid Can Alleviate Negative Affective States Caused by SPI1‐Induced Immune and Metabolic Dysfunctions Following Intestinal Barrier Impairment

open access: yesFood Frontiers, Volume 7, Issue 6, November 2026.
ABSTRACT Ulcerative colitis (UC) and depression (DP) are significant comorbidities in epidemiological research. However, the mechanisms underlying UC‐induced DP remain poorly understood. Myeloid differentiation and retinoic acid metabolic dysregulation are implicated in both conditions, yet their interconnection in the context of comorbidity is unclear.
Yang Feng   +7 more
wiley   +1 more source

Immune Checkpoint Inhibitor-Associated Cardiovascular Toxicity in Melanoma: Current Evidence and Practical Clinical Management. [PDF]

open access: yesCancers (Basel)
Bottardi A   +8 more
europepmc   +1 more source

Treatment‐Related Adverse Events and Health‐Related Quality of Life Associated With Immune Checkpoint Inhibitor Treatment for Mucosal Head and Neck Squamous Cell Carcinoma: A Scoping Review

open access: yesHead &Neck, Volume 48, Issue 11, Page 3152-3172, November 2026.
ABSTRACT Background Supportive care needs of patients receiving immune checkpoint inhibitors (ICIs) for head and neck squamous cell carcinoma (HNSCC) are ill‐defined. Hence, known treatment‐related adverse events (TRAEs) and health‐related quality of life (HRQoL) associated with ICI treatment for HNSCC were examined to inform future supportive care ...
N. D. O'Donnell   +11 more
wiley   +1 more source

Troponin I Surveillance to Risk-Stratify Early Events After Immune Checkpoint Inhibitor Initiation. [PDF]

open access: yesCirc Rep
Fujii H   +10 more
europepmc   +1 more source

Management of advanced mycosis fungoides and Sézary Syndrome: International Recommendations for systemic treatments and allogeneic hematopoietic cell transplantation from the European Hematology Association, the EORTC Cutaneous Lymphoma Tumours Group, the International Society for Cutaneous Lymphoma, and the Lymphoma Working Party of the EBMT

open access: yesHemaSphere, Volume 10, Issue 11, November 2026.
Abstract Advanced mycosis fungoides (MF) and Sézary syndrome (SS) are the most aggressive forms of cutaneous T‐cell lymphoma and remain associated with a poor prognosis and heterogeneous therapeutic approaches. Recent advances, including targeted therapies and improved transplant strategies, have substantially expanded treatment options, highlighting ...
Francesco Onida   +29 more
wiley   +1 more source

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