Treatment options for immune‐related adverse events associated with immune checkpoint inhibitors
British Journal of Pharmacology, EarlyView.Abstract The immunotherapy revolution with the use of immune checkpoint inhibitors (ICIs) started with the clinical use of the first ICI, ipilimumab, in 2011. Since then, the field of ICI therapy has rapidly expanded — with the FDA approval of 10 different ICI drugs so far and their incorporation into the therapeutic regimens of a range of malignancies.
Yu Hua Chen +3 more
wiley +1 more source
IDCasesMyocarditis is an inflammation of the heart muscle. The most common cause of myocarditis is viral infections. clinical presentation of acute myocarditis is highly variable and varies from asymptomatic to fulminant heart failure or sudden death. Fulminant
Behnam Shakerian +1 more
doaj
Parvovirus B19 infection causing pure red cell aplasia in a recipient of pediatric donor kidneys [PDF]
, 1993 Corral, DA +8 more
core +1 more source
Studies on the Experimental Myocarditis by the Lung-Phosphatide (I)
, 1954 SHUKICHI TAKAGI
openalex +2 more sources
Disseminated intravascular coagulation and myocarditis associated with Mycoplasma pneumoniae infection. [PDF]
, 1978 Sarah R. Pickens, J R Catterall
openalex +1 more source
Organoid Models to Study Human Infectious Diseases
Cell Proliferation, EarlyView.Our manuscript reviews the role of organoids as models for studying human infectious diseases, highlighting their irreplaceable contributions to drug testing and vaccine development for significant infectious diseases including HIV, ZIKV, SARS‐CoV‐2 and MPXV.
Sijing Zhu +4 more
wiley +1 more source
Single-cell transcriptomic analysis deciphers the inflammatory microenvironment characterized by CXCL9+ fibroblasts and ACKR1+ endothelial cells in immune-related myocarditis. [PDF]
J Transl MedSun B +11 more
europepmc +1 more source
Studies on the Experimental Myocarditis by the Lung-Phosphatide (IV)
, 1954 SHUKICHI TAKAGI
openalex +2 more sources
Varicella myocarditis presenting with unusual ventricular arrhythmias. [PDF]
, 1977 G I Fiddler +3 more
openalex +1 more source
Role of Histone Deacetylase and Inhibitors in Cardiovascular Diseases
Cell Proliferation, EarlyView.HDACs play an important role in the occurrence and development of cardiovascular diseases, such as myocardial hypertrophy, hypertension, and atherosclerosis. HDAC inhibitors have broad prospects for the treatment of CVD, and different HDAC subtypes can act through different mechanisms.
Li‐Ying Zhang +4 more
wiley +1 more source