Results 61 to 70 of about 130,790 (247)

The intersection of health inequalities and COVID‐19: Evidence from National Health Insurance Big Data in South Korea

American Journal of Community Psychology, EarlyView.
Abstract Health inequalities persist along lines of income and wealth, shaped by unequal access to healthcare, differences in health behaviors, and pre‐existing chronic conditions. The COVID‐19 pandemic further put families in Korea under health strain and worsened their health outcomes.
Jaehyun Nam, Sarah Jiyoon Kwon, Wonik Lee, Eunji Kim   +3 more
wiley   +1 more source

Targeted Anti‐IL‐1 Immunomodulatory Therapy in Pediatric Onset PPP1R13L‐Related Arrhythmogenic Cardiomyopathy

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Autosomal recessive loss‐of‐function variants in PPP1R13L cause an ultra‐rare cardiocutaneous syndrome characterized by rapidly progressive arrhythmogenic cardiomyopathy (ACM). PPP1R13L encodes iASPP, which has two potentially overlapping mechanisms driving ACM as both a regulator of NFκB‐mediated inflammation and a binding partner within the ...
Aaron Renberg, Savannah Coppersmith, Owen Merritt, Amer Heider, Adam Helms, Thomas Michniacki, Jack Luxford, Sarah Josephi‐Taylor, Philip Roberts, Joshua Meisner   +9 more
wiley   +1 more source

Causes of prehospital misinterpretations of ST elevation myocardial infarction [PDF]

, 2016
Objectives: To determine the causes of software misinterpretation of ST elevation myocardial infarction (STEMI) compared to clinically identified STEMI to identify opportunities to improve prehospital STEMI identification.
Bosson, Nichole, Eckstein, Marc, French, William J., Jollis, James G., Koenig, William, Kontos, Michael C., Macfarlane, Peter W., Niemann, James, Sanko, Stephen, Stickney, Ronald E., Tadeo, Richard, Taylor, Tyson G.   +11 more
core   +1 more source

Age and gender effects on echocardiographic and histopathological cardiac phenotypes in healthy adult mice

Animal Models and Experimental Medicine, EarlyView.
This study investigated the impact of age and sex on cardiac phenotypes in healthy adult C57BL/6J mice using echocardiography and histopathological analyses. Findings revealed that female mice demonstrated more pronounced global cardiac chamber dilation during aging.
Shuang Wen, Xijia Shao, Xiulin Zhang, Ningning Zhang, Xiao Chen, Guangxin Yue, Jiangping Song   +6 more
wiley   +1 more source

Adult-onset Still's disease: Evaluation of prognostic tools and validation of the systemic score by analysis of 100 cases from three centers [PDF]

, 2016
Background: Adult-onset Still's disease (AOSD) is rare inflammatory disease of unknown etiology that usually affects young adults. The more common clinical manifestations are spiking fevers, arthritis, evanescent rash, elevated liver enzymes ...
Berardicurti O., Carubbi F., Ciccia F., Cipriani P., Di Benedetto P., Giacomelli R., Guggino G., Iacono D., Liakouli V., Masedu F., Ruscitti P., Triolo G., Valenti M., Valentini G.   +13 more
core   +1 more source

Cancer therapy‐induced ototoxicity: Current challenges and emerging management strategies

Animal Models and Experimental Medicine, EarlyView.
This review comprehensively examines the key risk factors for cancer therapy‐induced ototoxicity, including cumulative drug dose, genetic susceptibility, and combined treatment regimens. It highlights current challenges in ototoxicity monitoring, such as insufficient timeliness and limited clinical adoption, and advocates for standardized auditory ...
Yuqi Huang, Baoying Xu, Xinru Chen, Yu Chen, Dehong Yu   +4 more
wiley   +1 more source

Neonatal Myocardial Infarction or Myocarditis? [PDF]

, 2011
We report a 29 week-gestation preterm infant who presented during his second week of life with cardiogenic shock. Clinical presentation and first diagnostics suggested myocardial infarction, but echocardiographic features during follow-up pointed to a ...
A Arthur, A Tillett, AJ Tometzki, Albertus Timmer, Beatrijs Bartelds, C Berry, D Bernstein, D Garel, D Inwald, DM Saker, DW Sapire, GE Burch, H Kilbride, IM Baldew, J Boulton, J Hruda, JM Morgan, Joost P. van Melle, KL Baughman, Klasien A. Bergman, L Abdurrahman, LA Iannone, Leanne de Vetten, LF Fagan, LG Hauwert Van der, M Fletcher, M Nathan, M Schryer, M Takeuchi, MH Gault, MZ Akkad, ND Reich, Nynke J. Elzenga, PF Lehoullier, S Ferns, S Sandhyamani, SJ Murugan, TS Hornung, VW Lucas Jr, WL Hu   +39 more
core   +2 more sources

Myocarditis Caused by Human Parechovirus in Adult

Emerging Infectious Diseases, 2017
The infectious etiology of myocarditis often remains unidentified. We report a case of myocarditis associated with human parechovirus (HPeV) infection in an adult.
Khai Lin Kong, Jillian S.Y. Lau, Su Mei Goh, Heather L. Wilson, Mike Catton, Tony M. Korman   +5 more
doaj   +1 more source

Interleukin‐5, Eosinophils, and Interleukin‐5 Pathway Inhibitors in Eosinophilic Granulomatosis With Polyangiitis

Arthritis &Rheumatology, EarlyView.
Interlukin‐5 (IL‐5) plays a crucial role in the pathogenesis of eosinophilic granulomatosis with polyangiitis (EGPA) by promoting eosinophil differentiation, activation, and survival. We present here a typical case of EGPA in which treatment with IL‐5 pathway inhibitors is prescribed, showing to be beneficial for the patient.
Alvise Berti, Christian Pagnoux
wiley   +1 more source

Prediction of Relapse and Glucocorticoid Dependence in Eosinophilic Granulomatosis With Polyangiitis: Findings From a Large European Cohort

Arthritis &Rheumatology, EarlyView.
Objective Eosinophilic granulomatosis with polyangiitis (EGPA) is a small vessel vasculitis characterized by eosinophilia, asthma, and ear, nose, and throat (ENT) involvement. Although glucocorticoids (GCs) are effective in controlling symptoms, relapses and GC dependence are common. The aim of this study was to develop predictive models for vasculitis
Matthias Papo, Pauline Martinot, Renato A. Sinico, Vítor Silvestre‐Teixeira, Nils Venhoff, Maria‐Letizia Urban, Michele Iudici, Juliane Mahrhold, Francesco Locatelli, Giulia Cassone, Franco Schiavon, Benjamin Seeliger, Thomas Neumann, Claudia Feder, Matthieu Groh, Chiara Marvisi, Maxime Samson, Thomas Barba, David Jayne, Arianna Troilo, Jens Thiel, Bernhard Hellmich, Sara Monti, Carlomaurizio Montecucco, Carlo Salvarani, Jean‐Emmanuel Kahn, Bernard Bonnotte, Cécile‐Audrey Durel, Xavier Puéchal, Luc Mouthon, Loïc Guillevin, Giacomo Emmi, Augusto Vaglio, Raphaël Porcher, Benjamin Terrier, on behalf of the French Vasculitis Study Group and the Eosinophilic Granulomatosis with Polyangiitis European Study Group   +35 more
wiley   +1 more source