Results 1 to 10 of about 40,104 (98)

Accumulation of metal(loid)s in myocardial tissue and the mechanisms underlying their cardiotoxic effects [PDF]

open access: yesMedicinski Podmladak, 2023
Heavy metals could exert a strong cardiotoxic effect, since cardiomyocytes are vulnerable cells in general, very sensitive to heavy metals-induced toxicity. The correlation between exposure to heavy metals and their contribution to the pathophysiology of
Ćirović Ana, Tasić Nebojša
doaj   +1 more source

Hypertrophic cardiomyopathy

open access: yesMedical Journal of Dr. D.Y. Patil Vidyapeeth, 2022
Hypertrophic cardiomyopathy (HCM) is a primary disease affecting the cardiac muscle and is characterized by heterogeneous genetic, morphological, functional and clinical features. The clinical presentation of HCM varies widely. Patients may be completely
Sarita Gore, Sunil Yogiraj Swami
doaj   +1 more source

Mechanism of stress heart damage in the animals of different sensitivity to hypoxia

open access: yesJournal of Education, Health and Sport, 2020
Hypoxia and resistance to it is the main in today data sitiuayion in the world.The aim of the study was to determine level of myocardium damage and corresponding of it with cytokines level in high- and low-resistance to hypoxic hypoxia rats (HR, LR) in ...
O. V. Denefil, Iu. M. Ordynskyi
doaj   +1 more source

Effect of the Novel Myotrope Danicamtiv on Cross‐Bridge Behavior in Human Myocardium

open access: yesJournal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2023
Background Omecamtiv mecarbil (OM) and danicamtiv both increase myocardial force output by selectively activating myosin within the cardiac sarcomere. Enhanced force generation is presumably due to an increase in the total number of myosin heads bound to
Joohee Choi   +3 more
doaj   +1 more source

Pathogenetic features of the nitric oxide system state in the left ventricular myocardium of the rats with experimental arterial hypertension

open access: yesJournal of Education, Health and Sport, 2020
The aim was to determine the pathogenetic features of the NO system in the myocardium of the left ventricle in the rats with endocrine-salt hypertension.Material and methods.
Mariia Igorivna Isachenko   +1 more
doaj   +1 more source

Submicroscopic changes of secretory cardiomyocytes under the experimental hyperglycemia in rats of different age groups

open access: yesВісник медичних і біологічних досліджень, 2022
Summary. Diabetes mellitus today is one of the most common diseases of humankind. One of the risk factors for heart disease in diabetes is chronic hyperglycemia, which causes cardiovascular disease and myocardial injury.
S.V. Trach Rosolovska   +3 more
doaj   +1 more source

Effect of Physical Training on the Activity of the Low Km Phosphodiesterase in Heart Ventricular and Skeletal Muscle Tissues of Normal and Diabetic Rats

open access: yesMcGill Journal of Medicine, 2020
This study assessed the effect of physical training on the low Michaelis constant cyclic AMP phosphodiesterase (low Km PDE) activity in heart ventricular tissue and three different skeletal muscle tissues of normal and diabetic rats.
Gilles Plourde, André Nadeau
doaj   +1 more source

Coronary Artery and Myocardium Injuries Induced by a High Cholesterol and Fructose Diet in Growing Male and Female Wistar Rats

open access: yesBulletin of University of Agricultural Sciences and Veterinary Medicine Cluj-Napoca: Veterinary Medicine, 2021
Cardiovascular disease (CVD) are mainly consequent of atherosclerosis.  Men develop CVD at a young age, this risk increases in women at an older age. Several studies have been carried out on male rats, but experiments on growing rats especially female ...
Lynda AÏNOUZ   +5 more
doaj   +1 more source

A possible relationship between gluconeogenesis and glycogen metabolism in rabbits during myocardial ischemia

open access: yesAnais da Academia Brasileira de Ciências, 2017
Ischemia is responsible for many metabolic abnormalities in the heart, causing changes in organ function. One of modifications occurring in the ischemic cell is changing from aerobic to anaerobic metabolism. This change causes the predominance of the use
RAQUEL R. DE AGUIAR   +7 more
doaj   +1 more source

Myocardial interstitial matrix as novel target for succinic acid treatment strategies during experimental hypobaric hypoxia

open access: yesRussian Open Medical Journal, 2019
Objective — Quantitative morphological studies of myocardial cellular elements. Aim of research is to study myocardial interstitial matrix with and without succinic acid treatment in the rats exposed to intermittent hypobaric hypoxia.
Igor V. Zadnipryany   +3 more
doaj   +1 more source

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