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Advances in the design, generation, and application of tissue-engineered myocardial equivalents

open access: yesFrontiers in Bioengineering and Biotechnology, 2023
Due to the limited regenerative ability of cardiomyocytes, the disabling irreversible condition of myocardial failure can only be treated with conservative and temporary therapeutic approaches, not able to repair the damage directly, or with organ ...
Giacomo Bernava, Laura Iop
doaj   +1 more source

Ultrastructural analysis of changes in myocardial blood microvessels in severe burn shock

open access: yesСибирский научный медицинский журнал, 2021
Burn injury is an important medical problem, as it is accompanied by high mortality rates in burn shock. Aim of the study was to conduct an ultrastructural stereological analysis of changes in the blood microvessels of the left ventricular myocardium in ...
S. V. Savchenko   +6 more
doaj   +1 more source

Depletion of VGLL4 Causes Perinatal Lethality without Affecting Myocardial Development

open access: yesCells, 2022
Congenital heart disease is one of the leading causes of pediatric morbidity and mortality, thus highlighting the importance of deciphering the molecular mechanisms that control heart development.
Caroline Sheldon   +4 more
doaj   +1 more source

Preconditioning boosts regenerative programmes in the adult zebrafish heart [PDF]

open access: yesOpen Biology, 2016
During preconditioning, exposure to a non-lethal harmful stimulus triggers a body-wide increase of survival and pro-regenerative programmes that enable the organism to better withstand the deleterious effects of subsequent injuries.
Anne-Sophie de Preux Charles   +4 more
doaj   +1 more source

SPECIFIC FEATURES OF INTERPRETATION OF MYOCARDIAL PERFUSION SINGLE-PHOTON EMISSION COMPUTED TOMOGRAPHY WITH COMPUTED TOMOGRAPHIC ABSORPTION CORRECTION

open access: yesВестник рентгенологии и радиологии, 2016
Objective: to study the capabilities of a hybrid single-photon emission computed tomography/computed tomography (SPECT/CT) system during myocardial perfusion imaging study, to evaluate the impact of absorption correction (AC), and to reveal factors ...
A. A. Ansheles
doaj   +1 more source

A New Role for Extracellular Vesicles in Cardiac Tissue Engineering and Regenerative Medicine

open access: yesAdvanced NanoBiomed Research, 2021
Cardiovascular diseases are the leading cause of death worldwide. Discovering new therapies to treat heart disease requires improved understanding of cardiac physiology at a cellular level. Extracellular vesicles (EVs) are plasma membrane‐bound nano‐ and
Karl T. Wagner, Milica Radisic
doaj   +1 more source

Micro RNAs AS BIOMARKERS FOR ACUTE MYOCARDIAL INFARCTION - SMALL MOLECULES WITH A HUGE POTENTIAL

open access: yesSanamed, 2015
MicroRNAs (miRNAs) are a conserved class of small, 17-25 nucleotides long, noncoding RNAs. They act as controllers of gene expression patterns, either by blocking translation or inducing miRNA degradation by sequence-specific hybridization.
Miskowiec Dawid, Kasprzak Jaroslaw D
doaj   +1 more source

Myocardial protective effect by ulinastatin via an anti-inflammatory response after regional ischemia/reperfusion injury in an in vivo rat heart model [PDF]

open access: yesKorean Journal of Anesthesiology, 2011
BackgroundUlinastatin has anti-inflammatory properties and protects organs from ischemia/reperfusion-induced injury. The aim of this study was to investigate whether ulinastatin provides a protective effect on a regional myocardial ischemia/reperfusion ...
Il-Woo Shin   +7 more
doaj   +1 more source

Specific Myocardial Lesion in a Patient with Diffuse Large B-Cell Lymphoma (a Case Report)

open access: yesКреативная хирургия и онкология, 2019
Introduction. Myocardial lymphoma is one of the rarest lesion localizations among all the lymphoproliferative diseases. Regardless of the current lack of generally accepted specific recommendations for the treatment of primary and secondary myocardial ...
D. D. Sakaeva   +3 more
doaj   +1 more source

Cardiac tissue engineering [PDF]

open access: yesJournal of the Serbian Chemical Society, 2005
We hypothesized that clinically sized (1-5 mm thick),compact cardiac constructs containing physiologically high density of viable cells (≈108 cells/cm3) can be engineered in vitro by using biomimetic culture systems capable of providing oxygen transport ...
Radišić Milica   +1 more
doaj   +1 more source

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