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Electroconductive Melt Electrowritten Patches Matching the Mechanical Anisotropy of Human Myocardium

open access: yesAdvanced Functional Materials, 2020
Cardiac patches represent a promising strategy for the treatment of myocardial infarction (MI). Here, an electroconductive cardiac patch that conforms to the mechanics of human myocardium is fabricated.
Michael G Monaghan
exaly   +2 more sources

Engineered Exosomes With Ischemic Myocardium‐Targeting Peptide for Targeted Therapy in Myocardial Infarction

open access: yesJournal of the American Heart Association, 2018
Background Exosomes are membranous vesicles generated by almost all cells. Recent studies demonstrated that mesenchymal stem cell–derived exosomes possessed many effects, including antiapoptosis, anti‐inflammatory effects, stimulation of angiogenesis ...
You Yu, Junjie Yang
exaly   +2 more sources

Depletion of VGLL4 Causes Perinatal Lethality without Affecting Myocardial Development

open access: yesCells, 2022
Congenital heart disease is one of the leading causes of pediatric morbidity and mortality, thus highlighting the importance of deciphering the molecular mechanisms that control heart development.
Caroline Sheldon   +4 more
doaj   +1 more source

Protective effects of Zingiber officinale extract on myocardium and placenta against labetalol-induced histopathological, immune-histochemical, and ultrastructural alterations in pregnant rats

open access: yesJournal of Basic and Applied Zoology, 2021
Labetalol is an antihypertensive drug commonly used in obstetrics for both long-term treatment and the acute management of severe maternal hypertension. However, there have not been published articles about the effects of labetalol on the myocardium and ...
H. El-Borm, Marwa N. Atallah
semanticscholar   +1 more source

Preconditioning boosts regenerative programmes in the adult zebrafish heart [PDF]

open access: yesOpen Biology, 2016
During preconditioning, exposure to a non-lethal harmful stimulus triggers a body-wide increase of survival and pro-regenerative programmes that enable the organism to better withstand the deleterious effects of subsequent injuries.
Anne-Sophie de Preux Charles   +4 more
doaj   +1 more source

A New Role for Extracellular Vesicles in Cardiac Tissue Engineering and Regenerative Medicine

open access: yesAdvanced NanoBiomed Research, 2021
Cardiovascular diseases are the leading cause of death worldwide. Discovering new therapies to treat heart disease requires improved understanding of cardiac physiology at a cellular level. Extracellular vesicles (EVs) are plasma membrane‐bound nano‐ and
Karl T. Wagner, Milica Radisic
doaj   +1 more source

Myocardial protective effect by ulinastatin via an anti-inflammatory response after regional ischemia/reperfusion injury in an in vivo rat heart model [PDF]

open access: yesKorean Journal of Anesthesiology, 2011
BackgroundUlinastatin has anti-inflammatory properties and protects organs from ischemia/reperfusion-induced injury. The aim of this study was to investigate whether ulinastatin provides a protective effect on a regional myocardial ischemia/reperfusion ...
Il-Woo Shin   +7 more
doaj   +1 more source

Cardiac tissue engineering [PDF]

open access: yesJournal of the Serbian Chemical Society, 2005
We hypothesized that clinically sized (1-5 mm thick),compact cardiac constructs containing physiologically high density of viable cells (≈108 cells/cm3) can be engineered in vitro by using biomimetic culture systems capable of providing oxygen transport ...
Radišić Milica   +1 more
doaj   +1 more source

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