Results 11 to 20 of about 188,396 (266)
Periostin-CCL3 Feedforward Signaling Loop Promotes Cardiac Fibrosis and Cardiomyocyte Necroptosis in Arrhythmogenic Cardiomyopathy. [PDF]
POSTN‐CCL3 signaling forms a feed‐forward circuit between cardiomyocytes and cardiac myofibroblasts in arrhythmogenic cardiomyopathy. POSTN activates JNK/RIP3‐dependent necroptotic signaling and JNK/ETS2‐induced CCL3 expression in cardiomyocytes. In turn, CCL3‐CCR5 signaling in cardiac myofibroblasts activates NF‐κB/p65 and promotes POSTN expression ...
Wu T +12 more
europepmc +2 more sources
Verapamil and the myocardium [PDF]
SummaryAlthough many of the drugs which recently have been developed for use in relieving angina pectoris display β-adrenoceptor blocking activity this property cannot be essential, because verapamil relieves angina pectoris without blocking the cardiac β-adrenoceptors.
W G, Nayler, D, Krikler
openaire +2 more sources
Estimation of postmortem interval by postmortem myocardial computed tomography value
Background: The estimation of postmortem interval (PMI) is one of the most important topics in forensic medicine research. We speculate that with an increased PMI, the computed tomography (CT) values of different tissues may show regular changes. Purpose:
Zhiyuan An +9 more
doaj +1 more source
The aim of the study is to perform an immunohistochemical analysis of the expression of the vascular endothelial growth factor receptor 2 (VEGFR2) in the myocardium of Wistar rats in doxorubicin-induced cardiomyopathy and the administration of betulonic ...
L. L. Elena +3 more
doaj +1 more source
The study of proteotomic profile of mutton with consideration to the influence of feed combinatorics
The present article is devoted to the search for markers that attest the changes in the protein profile when fattening the lambs with enriched diets, taking into account tissue specificity.
T. M. Giro +5 more
doaj +1 more source
Integrins and the Myocardium [PDF]
Abstract —Extracellular matrix provides a structural, chemical, and mechanical substrate that is essential in cardiac development, growth, and responses to pathophysiological signals. Transmembrane receptors termed integrins provide a dynamic interaction of environmental cues and intracellular events.
R S, Ross, T K, Borg
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Coronary heart disease is higly prevalent in many world countries including Russia, and for several decades cardiovascular disease are being the main reason for death and are regarded as serious medico-social problem.
V. E. Milyukov +2 more
doaj +1 more source
. Taking into account the conflicting data on the effect of the systemic inflammatory response on the structural and functional changes in the myocardium in clinical forms of tuberculosis, we conducted an echocardiographic study and an assessment of pro-
D. V. Kolchin +3 more
doaj +1 more source
Alternative Splicing of NOX4 in the Failing Human Heart
Increased oxidative stress is a major contributor to the development and progression of heart failure, however, our knowledge on the role of the distinct NADPH oxidase (NOX) isoenzymes, especially on NOX4 is controversial.
Zoltán V. Varga +20 more
doaj +1 more source
Out-of-hospital sudden cardiac arrest is a major public health problem with an overall survival of less than 5%. Upon cardiac arrest, cessation of coronary blood flow rapidly leads to intense myocardial ischemia and activation of the sarcolemmal Na+-H ...
Raúl J. Gazmuri +2 more
doaj +1 more source

