Decreased myocardial injury and improved contractility after administration of a peptide derived against the alpha-interacting domain of the L-type calcium channel. [PDF]
, 2014 BackgroundMyocardial infarction remains the leading cause of morbidity and mortality associated with coronary artery disease. The L-type calcium channel (IC a-L) is critical to excitation and contraction.
Hool, Livia C +3 more
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EFFECT OF SEVOFLURANE EXPOSURE ON ADRIAMYCIN-INDUCED INJURIES TO MYOCYTES
Российский кардиологический журнал, 2014 The study is to investigate the potential protective effect of sevoflurane on adriamycin induced myocyte injury. We prepared primary myocyte culture from neonatal rats and subjected the cells to adriamycin treatment.
Li-hua Fan +7 more
doaj +1 more source
IL-33 attenuates anoxia/reoxygenation-induced cardiomyocyte apoptosis by inhibition of PKCβ/JNK pathway. [PDF]
PLoS ONE, 2013 Interleukin-33 (IL-33) is a new member of the IL-1 cytokine family. The objectives of present study are to assess whether IL-33 can protect cardiomyocytes from anoxia/reoxygenation (A/R)-induced injury and the mechanism involved in the protection ...
Tao Rui, Qizhu Tang
doaj +1 more source
, 2016 Fibroblast-myocyte coupling can modulate electrical-wave dynamics in cardiac tissue. In diseased hearts, the distribution of fibroblasts is heterogeneous, so there can be gradients in the fibroblast density (henceforth we call this GFD) especially from ...
Pandit, Rahul, Zimik, Soling
core +1 more source
The meaning of different forms of structural myocardial injury, immune response and timing of infarct necrosis and cardiac repair [PDF]
, 2015 Although a decline in the all-cause and cardiac mortality rates following myocardial infarction (MI) during the past 3 decades has been reported, MI is a major cause of death and disability worldwide.
Bello, S +5 more
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Investigating interactions between epicardial adipose tissue and cardiac myocytes: what can we learn from different approaches? [PDF]
, 2017 Heart disease is a major cause of morbidity and mortality throughout the world. Some cardiovascular conditions can be modulated by lifestyle factors such as increased exercise or a healthier diet, but many require surgical or pharmacological ...
Agra +164 more
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Mst1 inhibition rescues β1-adrenergic cardiomyopathy by reducing myocyte necrosis and non-myocyte apoptosis rather than myocyte apoptosis [PDF]
Basic Research in Cardiology, 2015 It is generally held that inhibition of mammalian sterile 20-like kinase 1 (Mst1) protects the heart through reducing myocyte apoptosis. We determined whether inhibition with a dominant-negative Mst1 (DN-Mst1) would protect against the cardiomyopathy induced by chronic β1-adrenergic receptor (β1-AR) stimulation by preventing myocyte apoptosis.
Grace J, Lee +3 more
openaire +2 more sources
BDNF Actions in the Cardiovascular System: Roles in Development, Adulthood and Response to Injury
Frontiers in Physiology, 2019 The actions of BDNF (Brain-derived Neurotrophic Factor) in regulating neuronal development and modulating synaptic activity have been extensively studied and well established.
Pouneh Kermani +2 more
doaj +1 more source
miR126-5p Downregulation Facilitates Axon Degeneration and NMJ Disruption via a Non-Cell-Autonomous Mechanism in ALS. [PDF]
, 2018 Axon degeneration and disruption of neuromuscular junctions (NMJs) are key events in amyotrophic lateral sclerosis (ALS) pathology. Although the disease\u27s etiology is not fully understood, it is thought to involve a non-cell-autonomous mechanism and ...
Behar, Oded +10 more
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Biohybrid Soft Robots Powered by Myocyte: Current Progress and Future Perspectives
Micromachines, 2023 Myocyte-driven robots, a type of biological actuator that combines myocytes with abiotic systems, have gained significant attention due to their high energy efficiency, sensitivity, biocompatibility, and self-healing capabilities.
Zheng Yuan +4 more
doaj +1 more source