Results 81 to 90 of about 72,492 (253)

Three‐dimensional observation of the muscle–tendon integration process in mouse embryos

open access: yesDevelopmental Dynamics, EarlyView.
Abstract Background Muscle–tendon integration is a crucial step in the morphogenesis of the vertebrate locomotion system. As the limb muscle and tendon progenitor cells derive from distinct embryonic origin, their integration requires precise mutual positioning.
Ramu Sagasaki   +10 more
wiley   +1 more source

Ninjurin1 regulates striated muscle growth and differentiation.

open access: yesPLoS ONE, 2019
Chronic pressure overload due to aortic valve stenosis leads to pathological cardiac hypertrophy and heart failure. Hypertrophy is accompanied by an increase in myocyte surface area, which requires a proportional increase in the number of cell-cell and ...
Melanie Kny   +14 more
doaj   +1 more source

Quality Metrics for Stem Cell-Derived Cardiac Myocytes

open access: yesStem Cell Reports, 2014
Advances in stem cell manufacturing methods have made it possible to produce stem cell-derived cardiac myocytes at industrial scales for in vitro muscle physiology research purposes.
Sean P. Sheehy   +5 more
doaj   +1 more source

Differential effects of protamine sulfate on myocyte contractile function with left ventricular failure [PDF]

open access: yes, 1995
Objectives.This project tested two fundamental hypotheses: 1) Protamine sulfate has a direct and negative effect on myocyte contractile processes; 2) the negative effects of protamine on myocyte contractility will be enhanced in the setting of chronic ...
Francis G. Spinale   +5 more
core   +1 more source

Progression and prognostic significance of electrocardiographic findings in patients with cardiac amyloidosis

open access: yesESC Heart Failure, Volume 12, Issue 2, Page 809-818, April 2025.
Abstract Aims This study aimed to evaluate the change of the main electrocardiographic (ECG) characteristics and their prognostic role across the main subtypes of cardiac amyloidosis [light‐chain amyloidosis (AL) and hereditary (ATTRv) and wild‐type transthyretin amyloidosis (ATTRwt)].
Alessia Argirò   +20 more
wiley   +1 more source

The mAKAP signalosome and cardiac myocyte hypertrophy

open access: yes, 2007
Cardiac hypertrophy is regulated by a large intracellular signal transduction network. Each of the many signaling pathways in this network contributes uniquely to the control of cell growth.
Henson, Edward   +4 more
core   +1 more source

Meta‐analysis of sotagliflozin, a dual sodium‐glucose‐cotransporter 1/2 inhibitor, for heart failure in type 2 diabetes

open access: yesESC Heart Failure, Volume 12, Issue 2, Page 968-979, April 2025.
Abstract Sodium‐glucose co‐transporters (SGLTs) mediate sodium and glucose transport across cell membranes. SGLT2 inhibitors have a recognized place within heart failure (HF) guidelines. We evaluated the effect of sotagliflozin on HF and cardiovascular outcomes in participants with type 2 diabetes. Scopus, Medline, Embase and Central were searched from
Maria Anna Bantounou   +7 more
wiley   +1 more source

Distinct epigenetic programs regulate cardiac myocyte development and disease in the human heart in vivo

open access: yesNature Communications, 2018
How the cardiac myocyte epigenome is rearranged during development, postnatal maturation and disease is not well understood. Here, the authors investigate the human cardiac myocyte epigenome during development and chronic heart failure and identify ...
Ralf Gilsbach   +17 more
doaj   +1 more source

PVC triggering depends on the EAD myocyte-fibroblast pattern.

open access: yes, 2015
The top panels of (A), (B), (C), and (D) show the distribution of fibroblasts in a one dimensional cable of 280 cells, where blue, green, and brown indicate normal myocyte, EAD myocyte, and EAD myocyte-fibroblast composites, respectively.
Rahul Pandit (128415)   +2 more
core   +1 more source

Direct effects of oxygenated crystalloid or blood cardioplegia on isolated myocyte contractile function [PDF]

open access: yes, 1996
The majority of myocardial protective techniques performed in the United States incorporate hypothermic, hyperkalemic blood or crystalloid cardioplegia.
Handy, John R.   +6 more
core   +1 more source

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