Results 111 to 120 of about 143,705 (309)

Imaging Calcium Sparks in Cardiac Myocytes [PDF]

open access: yes, 2010
Calcium ions play fundamental roles in many cellular processes in virtually all type of cells. The use of Ca(2+) sensitive fluorescent indicators has proven to be an indispensable tool for studying the spatio-temporal dynamics of intracellular calcium ([Ca(2+)](i)).
Silvia, Guatimosim   +2 more
openaire   +2 more sources

Engineering Ultrasound Contrast Agents for Targeted Therapeutics: A Theranostic Approach to Drug Delivery, Gene Therapy, and Immunomodulation

open access: yesAdvanced NanoBiomed Research, EarlyView.
Ultrasound contrast agents, including microbubbles and nanobubbles, transform imaging and targeted therapy through precise engineering of size, shell composition, and surface properties. This review explores how these innovations enable tissue‐specific delivery, enhance therapeutic efficacy, and extend applications from vascular imaging to tumor ...
Ashkan Seza   +2 more
wiley   +1 more source

The organisation and functions of local Ca2+ signals [PDF]

open access: yes, 2001
Calcium (Ca2+) is a ubiquitous intracellular messenger, controlling a diverse range of cellular processes, such as gene transcription, muscle contraction and cell proliferation.
Berridge, Michael J.   +2 more
core  

Cardiac Myocytes and Mechanosensation

open access: yes, 2012
Mechanosensation is a fundamental process in biology and may have been developed by the early cells in response to hypo-osmotic stress [1]. With the evolution of different cell types and the appearance of multi-cellular organisms the mechanisms of mechanosensation and the corresponding transmission of signals became more complex and evolved in ...
Buyandelger, Byambajav, Knöll, Ralph
openaire   +4 more sources

Mitochondrial membrane potential in cardiac myocytes

open access: yesPhysiological Research, 2002
Mitochondria are involved in cellular functions that transcend the traditional role of these organelles as the energy factory of the cell. Their relative inaccessibility and the difficulties involved in attempts to study them in their natural environment - the cytosol - has delayed much of this understanding and they still have many secrets to yield ...
L, Skárka, B, Ostádal
openaire   +2 more sources

Confocal laser scanning microscope, raman microscopy and western blotting to evaluate inflammatory response after myocardial infarction [PDF]

open access: yes, 2015
Cardiac muscle necrosis is associated with inflammatory cascade that clears the infarct from dead cells and matrix debris, and then replaces the damaged tissue with scar, through three overlapping phases: the inflammatory phase, the proliferative phase
Cantatore, S   +6 more
core   +1 more source

Optimizing biophysical properties of cellular niches to enhance stem cell‐derived extracellular vesicle function in musculoskeletal regeneration

open access: yesBMEMat, EarlyView.
Extracellular vesicles (EVs) derived from stem cells show promise for applications in regenerative medicine, but their scalability and yield remain challenges. This review explores the approaches for biophysical modulations within cell niches on EV properties, discusses the current clinical application of EVs, and provides an outlook on the existing ...
Yang Xu   +9 more
wiley   +1 more source

Advanced glycation end product cross-link breaker attenuates diabetes-induced cardiac dysfunction by improving sarcoplasmic reticulum calcium handling

open access: yesFrontiers in Physiology, 2012
Diabetic heart disease is a distinct clinical entity that can progress to heart failure and sudden death. However, the mechanisms responsible for the alterations in excitation-contraction coupling leading to cardiac dysfunction during diabetes are not ...
Allyson eKranstuber   +6 more
doaj   +1 more source

Nuclear CaMKII enhances histone H3 phosphorylation and remodels chromatin during cardiac hypertrophy. [PDF]

open access: yes, 2013
Calcium/calmodulin-dependent protein kinase II (CaMKII) plays a central role in pathological cardiac hypertrophy, but the mechanisms by which it modulates gene activity in the nucleus to mediate hypertrophic signaling remain unclear. Here, we report that
An, Woojin   +7 more
core   +1 more source

Cardiac myocyte apoptosis [PDF]

open access: yesEuropean Heart Journal, 1999
S A, Cook, P A, Poole-Wilson
openaire   +2 more sources

Home - About - Disclaimer - Privacy