Results 191 to 200 of about 27,684 (229)

PRMT1 activates myogenin transcription via MyoD arginine methylation at R121

Biochimica Et Biophysica Acta - Gene Regulatory Mechanisms, 2019
MyoD is a determining transcription factor involved in myogenic cell differentiation. Post translational modifications of MyoD, including phosphorylation and acetylation, can regulate its transcription activity.
Ye Zhang
exaly   +2 more sources

Function of the myogenic regulatory factors Myf5, MyoD, Myogenin and MRF4 in skeletal muscle, satellite cells and regenerative myogenesis

Seminars in Cell and Developmental Biology, 2017
Peter Zammit
exaly   +2 more sources

MyoD-family inhibitor proteins act as auxiliary subunits of Piezo channels

Science, 2023
Piezo channels are critical cellular sensors of mechanical forces. Despite their large size, ubiquitous expression, and irreplaceable roles in an ever-growing list of physiological processes, few Piezo channel–binding proteins have emerged. In this work,
Zijing Zhou, Xiaonuo Ma, Yiechang Lin, D. Cheng, N. Bavi, G. Secker, J. Li, Vaibhao Janbandhu, Drew L. Sutton, H. Scott, Mingxi Yao, R. Harvey, N. Harvey, B. Corry, Yixiao Zhang, C. Cox   +15 more
semanticscholar   +1 more source

MyoD−E12 Heterodimers and MyoD−MyoD Homodimers Are Equally Stable

Biochemistry, 1997
Muscle development is controlled by the MyoD family of basic helix-loop-helix (bHLH) DNA-binding proteins. These proteins dimerize with ubiquitous products of the E2A gene (E12 and E47) and bind in a sequence-specific manner to enhancer regions of muscle-specific genes activating their expression.
S J, Maleki, C A, Royer, B K, Hurlburt
openaire   +2 more sources

MyoD and the transcriptional control of myogenesis

Seminars in Cell & Developmental Biology, 2005
The basic helix-loop-helix myogenic regulatory factors MyoD, Myf5, myogenin and MRF4 have critical roles in skeletal muscle development. Together with the Mef2 proteins and E proteins, these transcription factors are responsible for coordinating muscle-specific gene expression in the developing embryo.
Berkes, Charlotte A., Tapscott, Stephen J.   +1 more
openaire   +3 more sources

MyoD and Regulation of Prostaglandin H Synthase

Experimental Cell Research, 1993
MM14 myoblasts, in contrast to their differentiation defective variant (DD-1) cells, do not synthesize detectable levels of prostaglandins or of the initial enzyme in the pathway of prostaglandin synthesis, prostaglandin H synthase (PGHS) but do exhibit readily detectable level of PGHS mRNA (Steiner, S., et al., 1991, Exp. Cell Res. 192, 643).
J R, Wolf, Y, Hu, R R, Hirschhorn, S M, Steiner   +3 more
openaire   +2 more sources

Hypermethylated Myoblasts Specifically Deficient in MyoD Autoactivation as a Consequence of Instability of MyoD

Experimental Cell Research, 1996
MyoD is one of a family of basic helix loop helix (bHLH) transcription factors acting as master switches of skeletal muscle differentiation. In addition to transcriptionally activating differentiation-specific genes, it autoactivates its own expression through a positive feedback loop. It was cloned following the observation that treatment with the DNA
openaire   +2 more sources

Rat Monoclonal Antibody Specific for MyoD

Hybridoma, 2010
Myogenic determination 1 (MyoD) is a myogenic regulatory factor (MRF) possessing a basic domain and a helix-loop-helix domain. MRFs play a critical role in myoblast fate and terminal differentiation. MyoD is a transcriptional factor that induces transcription by binding with gene regulatory factors expressed in skeletal muscle.
Akihito, Harada, Yasuyuki, Ohkawa, Shinpei, Ao, Jun, Odawara, Seiji, Okada, Masayuki, Azuma, Yuko, Nishiyama, Mako, Nakamura, Taro, Tachibana   +8 more
openaire   +2 more sources

Humanized skeletal muscle in MYF5/MYOD/MYF6-null pig embryos

Nature Biomedical Engineering, 2021
G. Maeng, Satyabrata Das, Sarah M. Greising, W. Gong, Bhairab N. Singh, S. Kren, D. Mickelson, Erik Skie, O. Gafni, Jacob R. Sorensen, C. Weaver, D. Garry, M. Garry   +12 more
semanticscholar   +1 more source

MyoD and myogenesis in C. elegans

BioEssays, 1995
AbstractOne of the goals in developmental biology is the identification of key regulatory genes that govern the transition of embryonic cells from a pluripotent potential to a specific, committed cell fate. During vertebrate skeletal myogenesis, this transition is regulated by the MyoD family of genes. C.
openaire   +2 more sources