Results 71 to 80 of about 36,609 (227)

Welfare and Physiological Consequences of Non‐Lethal Blood Sampling From the Caudal Vasculature of Atlantic Salmon (Salmo salar L.)

Journal of Fish Diseases, EarlyView.
ABSTRACT The objective of this study was to evaluate welfare and health effects following single and repeated non‐lethal blood sampling from the caudal vasculature of Atlantic salmon. Two experiments were conducted at three different temperatures: a 6‐week freshwater experiment with fish weighing 50–100 g, undergoing up to four blood withdrawals, and a
Harriet Romstad, Camilla Karlsen, Silje Stensby‐Skjærvik, Alf Seljenes Dalum, Maria Banaszkiewicz, Simen Foyn Nørstebø, Jessica Louise Ray, Hege Lund, Torstein Kristensen, Christine Klykken   +9 more
wiley   +1 more source

Microgravity‐induced changes in skeletal muscle and possible countermeasures: What we can learn from bed rest and human space studies

Experimental Physiology, EarlyView.
Abstract Despite exercise countermeasures to sustain health and performance in spaceflight, complete maintenance of muscle mass and functions in microgravity is still not possible for most astronauts. The principal cause of the limited effectiveness of existing exercise countermeasures is the difficulty in achieving full loading forces in space.
Alessandra Bosutti, Bergita Ganse, Nicola A. Maffiuletti, Rob C. I. Wüst, Gustav J. Strijkers, Andy Sanderson, Hans Degens   +6 more
wiley   +1 more source

Differential regulation of myofibrillar proteins in skeletal muscles of septic mice

Physiological Reports, 2019
Sepsis elicits skeletal muscle atrophy as a result of decreased total protein synthesis and/or increased total protein degradation. It is unknown how and whether sepsis differentially affects the expression of specific myofibrillar proteins in ...
Vanessa Moarbes, Dominique Mayaki, Laurent Huck, Philippe Leblanc, Theodoros Vassilakopoulos, Basil J. Petrof, Sabah N. A. Hussain   +6 more
doaj   +1 more source

Turning over new ideas in human skeletal muscle proteostasis: What do we know and where to from here?

Experimental Physiology, EarlyView.
Abstract Understanding the turnover of proteins in tissues gives information as to how external stimuli result in phenotypic change. Nowhere is such phenotypic change more conspicuous than skeletal muscle, which can be effectively remodelled by increased loading, ageing and unloading (disuse), all of which are subject to modification by nutrition and ...
Changhyun Lim, James McKendry, Matthew Lees, Philip J. Atherton, Nicholas A. Burd, Andrew M. Holwerda, Luc J. C. van Loon, Chris McGlory, Cameron J. Mitchell, Kenneth Smith, Daniel J. Wilkinson, Tanner Stokes, Stuart M. Phillips   +12 more
wiley   +1 more source

Skeletal Muscle Myofibrillar Protein Abundance Is Higher in Resistance-Trained Men, and Aging in the Absence of Training May Have an Opposite Effect

Sports, 2020
Resistance training generally increases skeletal muscle hypertrophy, whereas aging is associated with a loss in muscle mass. Interestingly, select studies suggest that aging, as well as resistance training, may lead to a reduction in the abundance of ...
Christopher G. Vann, Paul. A. Roberson, Shelby C. Osburn, Petey W. Mumford, Matthew A. Romero, Carlton D. Fox, Johnathon H. Moore, Cody T. Haun, Darren T. Beck, Jordan R. Moon, Andreas N. Kavazis, Kaelin C. Young, Veera L. D. Badisa, Benjamin M. Mwashote, Victor Ibeanusi, Rakesh K. Singh, Michael D. Roberts   +16 more
doaj   +1 more source

Altered splicing of the BIN1 muscle-specific exon in humans and dogs with highly progressive centronuclear myopathy [PDF]

, 2013
Amphiphysin 2, encoded by BIN1, is a key factor for membrane sensing and remodelling in different cell types. Homozygous BIN1 mutations in ubiquitously expressed exons are associated with autosomal recessive centronuclear myopathy (CNM), a mildly ...
A Buj-Bello, A Lujan Feliu-Pascual, A Razzaq, A Tjondrokoesoemo, A Toussaint, AC Durieux, AH Beggs, AJ Muller, Anne Toussaint, AS Nicot, AY Mejaddam, B Qualmann, B Sinha, Belinda Cowling, BJ Peter, BS Cowling, C Fugier, C Kojima, C Spiegelhalter, CJ McMillan, CR Pierson, D Bansal, D Grabs, D Sakamuro, DJ Owen, E Lee, G Di Paolo, G Ren, G. Diane Shelton, Gregory A. Cox, H Jungbluth, Ivana Prokic, J Bohm, J Laporte, J Weis, JJ Dowling, Joachim Weis, Jocelyn Laporte, Johann Böhm, KC Chang, KG Claeys, L Klinge, Laurent Tiret, M Bitoun, M Maurer, M Pele, Marie Maurer, MH Butler, Nasim Vasli, NB Romero, NC Mao, R Wechsler-Reya, RJ Wechsler-Reya, S Pant, SE Davies, T Itoh, Thomas James Anderson, Ulrike Schara, Wolfram Kress   +58 more
core   +7 more sources

The effect of bed rest, unilateral limb immobilization and head‐down tilt on muscle protein synthesis: A systematic review and meta‐analysis

Experimental Physiology, EarlyView.
Abstract Muscle disuse leads to muscle atrophy and a decrease in muscle function that is primarily driven by reduced muscle protein synthesis (MPS). The aim of this systematic review and meta‐analysis was to examine the effect of different models of muscle disuse on rates of MPS.
Konstantinos Prokopidis, Paul T. Morgan, Colleen S. Deane, Oliver C. Witard, David D. Church   +4 more
wiley   +1 more source

Study on the Synergistic Effect and Mechanism of Octenyl Succinic Anhydride-Modified Starch on the Stability of Myofibrillar Protein Emulsion

Chemistry
The effects of octenyl succinic anhydride-modified hydrophobic starch (OSA starch) on the properties of myofibrillar protein (MP) emulsions were investigated.
Peipei Yin, Xiaozhong Bi, Yuyu Xu, Tianhao Zhu, Qing Yin, Qingling Wang, Mangang Wu   +6 more
doaj   +1 more source

Myocellular adaptations to short‐term weighted wheel‐running exercise are largely conserved during C26‐tumour induction in male and female mice

Experimental Physiology, EarlyView.
Abstract This study investigated whether performing a translatable murine model of concurrent training after tumour induction affects adaptations in juvenile male and female tumour‐bearing mice. Male and female Balb/c mice were injected bilaterally with colon‐26 adenocarcinoma (C26) cells or PBS at 8 weeks of age.
Stavroula Tsitkanou, Pieter Koopmans, Calvin Peterson, Ana Regina Cabrera, Ruqaiza Muhyudin, Francielly Morena, Sabin Khadgi, Eleanor R. Schrems, Tyrone A. Washington, Kevin A. Murach, Nicholas P. Greene   +10 more
wiley   +1 more source

Applying lessons from limb muscle disuse and ageing to better understand ventilator‐induced diaphragm dysfunction

Experimental Physiology, EarlyView.
Abstract Mechanical ventilation (MV) is a life‐saving intervention applied to critically ill patients. A common consequence of MV is ventilator‐induced diaphragm dysfunction (VIDD), which is characterized by significant diaphragm atrophy and reduced contractile function. Older patients who receive MV are more likely to develop VIDD, have worse recovery,
P. H. C. Mesquita, J. L. Halle, J. D. Fuqua, B. F. Miller   +3 more
wiley   +1 more source