Results 51 to 60 of about 3,612,626 (256)
RUNX1‐Mediated Hypoxic Signaling Impairs Myogenesis and Promotes Fibrosis in Myopathies
Advanced Science, EarlyView.Myofiber overgrowth was associated with reduced blood flow and a potential hypoxic state in broiler breast muscle, accompanied by increased RUNX1 expression. Elevated RUNX1 impaired myogenic regeneration, promoted fibrosis, and disrupted the signaling niche required for efficient muscle repair, contributing to pathological degeneration in Wooden Breast
Liang Zhao +4 more
wiley +1 more source
Myofibrillar protein synthesis in myostatin-deficient mice [PDF]
American Journal of Physiology-Endocrinology and Metabolism, 2006 Either increased protein synthesis or prolonged protein half-life is necessary to support the excessive muscle growth and maintenance of enlarged muscles in myostatin-deficient mice. This issue was addressed by determining in vivo rates of myofibrillar protein synthesis in mice with constitutive myostatin deficiency (MstnΔE3/ΔE3) or normal myostatin ...
Stephen, Welle +2 more
openaire +2 more sources
Animal Research and One Health, EarlyView.Integrated phenotypic, histological, transcriptomic, and validation analyses reveal that emaciation syndrome in Plectropomus leopardus is associated with intestinal structural damage, hepatic metabolic remodeling, and muscle protein degradation, highlighting coordinated multi‐tissue alterations underlying disease progression.
Zhihao Zhang +11 more
wiley +1 more source
Effect of Processing Methods on Protein Oxidation of Beef
Shipin gongye ke-ji, 2022 In order to study the changes of protein oxidation during heat processing, cattle tendon and shoulder were treated at different temperatures (40, 50, 60, 70, 80, 90, 100 ℃, holding time 30 min) and at 70 kPa high pressure for different times (15, 20, 25,
Yuanyuan DAI +4 more
doaj +1 more source
Animal Research and One Health, EarlyView.Multifunctional roles of functional amino acids in regulating meat quality in ruminants: Functional amino acids (FAAs) regulate ruminant meat quality through multiple interconnected mechanisms, including antioxidant protection, metabolic regulation, signal transduction, structural support, and gene expression modulation.
Zixin Liu +5 more
wiley +1 more source
Molecules, 2022 The changes in the gel and rheological properties and water-holding capacity of PSE meat myofibrillar proteins with different amounts of sodium bicarbonate (SC, 0–0.6/100 g) were studied.
Zhong-Wei Wu +4 more
doaj +1 more source
Extralysosomal Protein Degradation in Myofibrillar Myopathies
Brain Pathology, 2009 AbstractMyofibrillar myopathies (MFMs) are a group of heterogeneous muscle disorders morphologically defined by the presence of foci of dissolution of the myofibrils, accumulation of the products of myofibrillar degradation and ectopic expression of multiple proteins.
openaire +3 more sources
Cytoskeleton, EarlyView.ABSTRACT The cytoskeleton of striated muscle integrates force transmission, mechanotransduction, and sarcolemmal stability through coordinated networks of sarcomeres, costameres, and intermediate filaments. Together, these systems establish mechanical continuity between the contractile apparatus, the sarcolemma, and the extracellular matrix.
Houda Cohen +3 more
wiley +1 more source
Cytoskeleton, EarlyView.ABSTRACT We here describe mouse models with complementary homozygous Svil mutations. In skeletal muscle, Svil‐Mut mice express the Svil‐encoded N‐terminus fused to the βgal‐neo gene‐trap tag and lack the highly conserved archvillin C‐terminus; Svil‐KO mice lack expression of all known Svil‐encoded proteins; and Svil‐LoxP mice contain loxP sites for ...
Tara C. Smith +9 more
wiley +1 more source
, 1998 This study tested the hypothesis that increasing the protein content of isocaloric meals increases the rate of myofibrillar synthesis in muscle of healthy subjects over 60 yr old and enhances the stimulation of myofibrillar synthesis induced by ...
Stephen Welle, Charles A. Thornton
core +1 more source