Results 41 to 50 of about 21,460 (265)

Diarrhea reduces the rates of cardiac protein synthesis in myofibrillar protein fractions in rats in vivo

, 2001
Although chronic diarrhea affects heart function and morphology, the pathogenic mechanisms are unknown. It was our hypothesis that diarrhea imposes metabolic stress to inhibit the synthesis of new contractile proteins.
Hunter, R.V., Patel, V., Wong, H.J., Richardson, P., Preedy, V.R., Miell, J., Marway, J.   +6 more
core   +2 more sources

The influence of carbohydrate-protein co-ingestion following endurance exercise on myofibrillar and mitochondrial protein synthesis

, 2011
The aim of the present study was to determine mitochondrial and myofibrillar muscle protein synthesis (MPS) when carbohydrate (CHO) or carbohydrate plus protein (C+P) beverages were ingested following prolonged cycling exercise.
Philp, A, Keith Baar, Selby, A, Baar, Keith, Sarah R. Jackman, Ken Smith, Baar, K, Philp, Andrew, Leigh Breen, Tipton, Kevin, Witard, OC, Jackman, Sarah, Kevin D. Tipton, Breen, Leigh, Smith, Kenneth, Anna Selby, Jackman, Sarah R, Andrew Philp, Oliver C. Witard, Witard, Oliver, Smith, K, Selby, Anna   +21 more
core   +1 more source

Presleep dietary protein-derived amino acids are incorporated in myofibrillar protein during postexercise overnight recovery [PDF]

, 2018
The purpose of this study was to determine the impact of ingesting 30 g casein protein with and without 2 g free leucine before sleep on myofibrillar protein synthesis rates during postexercise overnight recovery. Thirty-six healthy young men performed a
Imre W. K. Kouw, Rollo, Ian, Andrew M. Holwerda, Shona L. Halson, Tim Snijders, Kouw, Imre W. K., Snijders, Tim, van Loon, Luc J. C., Trommelen, Jorn; id_orcid, Snijders, Tim; id_orcid, Halson, Shona L., Holwerda, Andrew M., Trommelen, Jorn, Jorn Trommelen, Lex B. Verdijk, Verdijk, Lex B., Luc J. C. van Loon, Ian Rollo   +17 more
core   +1 more source

Microenvironmental Reprogramming by 3D Anisotropic Cardiac Extracellular Matrix Induces Nuclear Remodeling and Epigenetic Maturation of Chemically Induced Cardiomyocytes

Advanced Functional Materials, EarlyView.
A 3D anisotropic hydrogel derived from heart extracellular matrix guides cytoskeletal alignment and nuclear remodeling in reprogrammed cardiomyocyte‐like cells. This study reveals how matrix alignment modulates nuclear envelope dynamics and chromatin state, triggering transcriptional and functional maturation.
Seung Ju Seo, Mi Jeong Lee, Hyun Wook Kang, Seonhee Byeon, Soo‐Kyoung Choi, Nakwon Choi, Seung‐Woo Cho, Yoonhee Jin   +7 more
wiley   +1 more source

Effect of adding concentrated myofibrillar proteins of silver carp (Hypophthalmichthys molitrix) on the qualitative and nutritional characteristics of pasta [PDF]

تغذیه آبزیان
Introduction: Pasta is a traditional grain-based food product that is popular worldwide. Wheat protein lacks some essential amino acids, which should be provided from the other sources to meet consumers' needs.
Mahsa Karami Charvadeh, Eshagh Zakipour Rahimabadi, Parva Safari   +2 more
doaj   +1 more source

Effect of Ultrasound-Assisted Sodium Bicarbonate Treatment on Aggregation and Conformation of Reduced-Salt Pork Myofibrillar Protein

Molecules, 2022
To study the effects of an ultrasound (0, 30, and 60 min) and sodium bicarbonate (0% and 0.2%) combination on the reduced-salt pork myofibrillar protein, the changes in pH, turbidity, aggregation, and conformation were investigated.
Zhuang-Li Kang, Xue-Yan Shang, Yan-Ping Li, Han-Jun Ma   +3 more
doaj   +1 more source

Microfabricated Anisotropic Myobundles for the Scalable Production of Cardiac Tissue Grafts

Advanced Functional Materials, EarlyView.
Controlling the anisotropy of cardiac tissue remains an outstanding challenge in the field of cardiac tissue engineering. Here, we introduce an approach to generate anisotropic cardiac myobundles using cell‐adhesive, synthetic, electrospun fibers and stem cell‐derived cardiac fibroblasts.
Maggie E. Jewett, Javiera Jilberto, Margaret E. Stanley, David O. Ntim, Siddhi M. Bhirud, Avianna T. Schroeder, Gonzola X. Anyosa Galvez, Jingyi Xia, Samuel J. DePalma, Emmanouil Agrafiotis, Susan S. Xi, Amanda S. Bluem, Courtney M. Lestock, Adam S. Helms, David A. Nordsletten, Brendon M. Baker   +15 more
wiley   +1 more source

Myofibrillar muscle protein synthesis rates subsequent to a meal in response to increasing doses of whey protein at rest and after resistance exercise

, 2014
Background: The intake of whey, compared with casein and soy protein intakes, stimulates a greater acute response of muscle protein synthesis (MPS) to protein ingestion in rested and exercised muscle.
Breen, Leigh, Smith, Kenneth, Jackman, Sarah R, Witard, Oliver, Tipton, Kevin, Selby, Anna   +5 more
core   +1 more source

Degradation of myofibrillar proteins by cathepsins B and D [PDF]

Biochemical Journal, 1977
Cathepsin B and cathepsin D were purified from rat liver and skeletal muscle. Electrophoretic analyses revealed that the enzymes were highly purified, and isoelectric focusing demonstrated multiple forms of both enzymes. Purified actin and myosin, as well as actin and myosin in myofilaments and myofibrils, were degraded by the purified cathepsins B and
J W, Bird, W N, Schwartz, A M, Spanier
openaire   +4 more sources

G3BP1 Succinylation at K413 is Critical for Cardiac Function by Modulating PI3K‐AKT‐mTOR Signal Axis

Advanced Science, EarlyView.
Schematic illustrating the impact of G3BP1 succinylation at K413 on cardiac function. In the healthy human heart, G3BP1 succinylation maintains homeostatic mTOR signaling. In patients with dilated cardiomyopathy (DCM) and heart failure (HF), G3BP1 de‐succinylation induces RagA expression and disrupts the binding of the TSC1/2 complex, leading to the ...
Yuan Zhang, Cancan Yao, Yan Chen, Ke Cai, Zhouping Lu, Boxuan Wu, Kun Yu, Yan Shi, Jianyuan Zhao, Xiangyu Zhou   +9 more
wiley   +1 more source