Sacubitril/valsartan preserves regional cardiac function following myocardial infarction in rats
ESC Heart Failure, Volume 12, Issue 2, Page 1304-1315, April 2025.Parts of the figure were drawn by using pictures from Servier Medical Art. Servier Medical Art by Servier is licensed under a Creative Commons Attribution 3.0 Unported License (https://creativecommons.org/licenses/by/3.0/). Abstract Aims Sacubitril/valsartan (Sac/Val) is used for treatment of heart failure. The effect of Sac/Val on regional dysfunction
Einar Sjaastad Nordén +16 more
wiley +1 more source
Micro Pattern‐Based 3D Cell Culture Platform: An Overview of Technologies and Applications
Exploration, EarlyView.Micro patterns are characterized as a coating of specific adhesion matrices on substrates to support cell growth. An overview of micropattern technology to regulate single cell morphology and fates, further focusing on the micro pattern‐based 3D cell culture platform used in the non‐tumor and tumor researches.
Xinglong Zhu +8 more
wiley +1 more source
Exploration, EarlyView.This study innovates a Ca2+‐responsive hydrogel dressing that releases AIE photosensitizers on‐demand. Low Ca2+ enhances bacterial hyaluronidase (HAase) activity, degrading hyaluronic acid dressing to trigger antibacterial ROS release, while high Ca2+ inhibits HAase, preventing overdosing.
Rongwei Cui +12 more
wiley +1 more source
Microengineering the Liver: Strategies for Constructing Functional Liver‐on‐a‐Chip Devices
Exploration, EarlyView.This review summarizes recent advances in liver‐on‐a‐chip (LOC) technologies, including fabrication strategies and functional integration approaches, and discusses their promising applications in drug screening and related biomedical fields. ABSTRACT Reliable in vitro liver models are indispensable for researching liver diseases and developing ...
Jie Wang +7 more
wiley +1 more source
Beyond Organ-Specific Therapies: A Unified Approach to Multi-Organ Fibrosis. [PDF]
Drug Des Devel TherPan Z +5 more
europepmc +1 more source
Harnessing Free Radical Scavenging Potential of Caffeic Acid as a Nutraceutical—A Review
Food Safety and Health, EarlyView.Caffeic acid has emerged as a promising bioactive molecule with multiple pharmacological properties, including antioxidant, antimicrobial, anti‐inflammatory, organ protective properties and metal‐chelating ability. This review emphasizes the dietary sources, structural characteristic, molecular mechanism underlying health promoting effects of caffeic ...
Pavitra Behra +2 more
wiley +1 more source
Comment on "Dectin-1 is Pathogenic in Chronic Kidney Disease by Promoting Macrophage Infiltration and Transition to Myofibroblast". [PDF]
Int J Biol SciLiu D, Che X, Wu G.
europepmc +1 more source
Apoptosis inhibition reprograms alveolar myofibroblasts toward ductal myofibroblasts
ABSTRACTThe epithelial tree of the lung is shaped proximo-distally by airway smooth muscle cells (ASMCs), ductal myofibroblasts (DMFs), and, transiently, alveolar myofibroblasts (AMFs). Lineage tracing and snapshot imaging suggest the clearance of AMFs via apoptosis post-alveologenesis, although definitive evidence is lacking.
Maria Jose Gacha-Garay +4 more
openaire +1 more source
Myogenic Differentiation (MyoD) Gene Expression in Cornea and Role in Corneal Myofibroblast Dedifferentiation. [PDF]
Invest Ophthalmol Vis SciTripathi R +9 more
europepmc +1 more source