Results 211 to 220 of about 73,235 (299)

Proliferative vitreoretinopathy: An integrative, multi‐pathway perspective on pathogenesis and therapy

Acta Ophthalmologica, EarlyView.
Abstract Proliferative vitreoretinopathy (PVR) remains the principal biological cause of failed retinal detachment repair. Classical pathogenic models centred on retinal pigment epithelium (RPE) dispersion, retinal injury responses or compartment‐restricted mechanisms do not fully explain the heterogeneity, biomechanical behaviour and clinical ...
Koen A. van Overdam, J. Sebag
wiley   +1 more source

Human Urine Stem Cells Alleviate Pulmonary Fibrosis via Inhibiting Macrophage-Myofibroblast Transition. [PDF]

Adv Sci (Weinh)
Zhang ZH, Guo GL, Guan XH, Hu M, Huang QM, Guo DW, Gu HC, Zhuo YQ, Li N, Xin HB, Deng KY.   +10 more
europepmc   +1 more source

Neovascular glaucoma at a tertiary Centre in Finland, 2008–2024: A retrospective cohort study

Acta Ophthalmologica, EarlyView.
Abstract Purpose Neovascular glaucoma (NVG) is a refractory secondary glaucoma, yet longitudinal outcome data remain limited. This study reports its aetiologies, treatments and outcomes. Methods Patients with NVG were identified through electronic medical record review.
Gilbert Simons, Mikael von Fersen, Paula Summanen, Mika Harju   +3 more
wiley   +1 more source

Monoamine Oxidase B (MAO-B) as an Inducer of Mitochondrial Reactive Oxygen Species (ROS) Production and Myofibroblast Differentiation in Cardiac Fibroblasts of Mice. [PDF]

Cells
Euler G, Disch H, Trautmann M, Bernhardt A, Krechmeier J, Schulz R, Heger J.   +6 more
europepmc   +1 more source

Atg5 deficiency alters myofibroblast accumulation and alveolar regeneration in lung fibrosis. [PDF]

Stem Cell Reports
Li X, Xu G, Wang Q, Ma Q, Liu X, Li H, Wang S, Liu Y, Jin Y, Miao X, He Z, Dong J, Li K, Wang J, Li Y, Zhang Q, Jiang D, Wu J, Ning W, Chen H.   +19 more
europepmc   +1 more source

Brain metastasis‐associated fibroblasts shape the tumour microenvironment to enhance cancer cell invasion

Brain Pathology, EarlyView.
Brain metastasis‐associated fibroblasts are active stromal components of the metastatic niche characterised by extracellular matrix remodelling and production of pro‐migratory mediators. They promote monocyte and cancer cell migration and enhance cancer cell invasion while having no growth‐promoting effect on cancer cells.
Barbora Výmolová, Lucie Pfeiferová, Tadeáš Karel Smetana, Petr Výmola, Nikola Ternerová, Michal Zubaľ, Michal Kolář, Jana Šáchová, Soňa Gyönyörová, Eva Balážiová, Magdalena Houdová Megová, Jakub Červenka, Helena Kupcová Skalníková, Michal Španko, Karel Smetana Jr., Lukáš Lacina, David Netuka, Robert Tomáš, Petr Bušek, Aleksi Šedo   +19 more
wiley   +1 more source

A PIEZO-Gated Mechanotransduction Timing Window Governs Scar Commitment in Wound Healing. [PDF]

Wound Repair Regen
Hamad RS, Ali MAM, Chaudhary AA, Elmorsy EA, Amer MM, Abdel-Hamed MR, El-Kott AF, Eltantawy W, AlShehri MA, Eissa H, Farrag AA, Saber S.   +11 more
europepmc   +1 more source

Honokiol regulates Acute respiratory distress syndrome (ARDS)‐associated pulmonary fibrosis via the miR‐19a‐3p/POSTN axis

British Journal of Pharmacology, EarlyView.
Abstract Background and Purpose Acute respiratory distress syndrome (ARDS) and subsequent pulmonary fibrosis are associated with high mortality and limited treatment options. Periostin (POSTN) is a profibrotic mediator predicted to be regulated by microRNA‐19a‐3p (miR‐19a‐3p), but the relevance of this axis in ARDS‐associated pulmonary fibrosis remains
Weilun Liu, Hsiaohsuan Wang, Hsuanfu Kuo, Chiahung Yen, Modasang Hua, Chiayuan Chang, Zhiwei Xu, Ifan Liu, Chongchao Hsieh, Chihhsin Hsu, Chiayang Li, Shuchi Wang, Yunghsiang Chen, Menghsuan Cheng, Polen Liu   +14 more
wiley   +1 more source

IRF7 links HK1-dependent histone lactylation to fibroblast activation and cardiac fibrosis. [PDF]

EMBO Mol Med
Kong M, Zhu C, Xue Y, Hong W, Zhang G, Jiang D, Xu Y, Guo J.   +7 more
europepmc   +1 more source

Beyond Inflammation: Breaking the Vicious Cycle of Matrix Stiffness and Mechanotransduction in Systemic Sclerosis. [PDF]

Int J Rheum Dis
Cheng TK, Misra DP, Wei JC.
europepmc   +1 more source