Results 31 to 40 of about 94,921 (285)

Cytoglobin as a Marker of Hepatic Stellate Cell-derived Myofibroblasts

Frontiers in Physiology, 2015
Myofibroblasts play important roles in inflammation, fibrosis and tumorigenesis in chronically inflamed liver. Liver myofibroblasts originate from hepatic stellate cells, portal fibroblasts or mesothelial cells, and they are localized in and around ...
Norifumi eKawada
doaj   +1 more source

The Yin and Yang of Mesenchymal Cells in the Corneal Stromal Fibrosis Response to Injury: The Cornea as a Model of Fibrosis in Other Organs

Biomolecules, 2022
Mesenchymal cells (keratocytes, corneal fibroblasts, and myofibroblasts), as well as mesenchymal progenitor bone marrow-derived fibrocytes, are the major cellular contributors to stromal fibrosis after injury to the cornea.
Steven E. Wilson
doaj   +1 more source

Deletion of EP4 in S100a4-lineage cells reduces scar tissue formation during early but not later stages of tendon healing [PDF]

, 2017
Tendon injuries heal via scar tissue rather than regeneration. This healing response forms adhesions between the flexor tendons in the hand and surrounding tissues, resulting in impaired range of motion and hand function.
Ackerman, Jessica E, Best, Katherine T, Loiselle, Alayna E, O’Keefe, Regis J   +3 more
core   +2 more sources

Immunohistochemical evaluation of myofibroblasts using alpha-smooth muscle actin in oral submucous fibrosis

SRM Journal of Research in Dental Sciences, 2014
Introduction: Oral submucous fibrosis (OSMF) is a chronic debilitating disease and a premalignant condition of the oral cavity characterized by generalized submucosal fibrosis with a multifactorial etiology.
Teena Philip, T Dinesh Kumar, K Rajkumar, K Raghavendhar Karthik, N Priyadharsini, A Ramesh Kumar   +5 more
doaj   +1 more source

Hyaluronidase pharmacological properties and clinical application in ophthalmology

Сибирский научный медицинский журнал, 2020
Corneal diseases are the fourth leading cause of blindness in the world, accounting for approximately 5 % of cases. Existing methods of treatment in more than 30 % of cases do not have a full therapeutic effect and when the process is stopped, they end ...
V. E. Zabanova, A. Zh. Fursova, P. G. Madonov   +2 more
doaj   +1 more source

Giant Intramuscular Nodular Fasciitis Masquerading as Soft Tissue Sarcoma with Neural Involvement - A Case Report [PDF]

Journal of Clinical and Diagnostic Research, 2016
Nodular Fasciitis (NF) is described as a benign reactive proliferation of myofibroblasts that occurs predominantly in the subcutaneous location. Most commonly presents as rapidly growing swelling in the young adults, with usual size of less than 4cm and
Anandhi Amaranathan, Vishnu Prasad Nelamangala Ramakrishnaiah, Susan Rajan, Rajesh Nachiappa Ganesh   +3 more
doaj   +1 more source

Cytotoxic Influence of Khat (Catha edulis (Vahl) Forssk. ex Endl) on Oral Fibroblasts, Squamous Carcinoma Cells, and Expression of α Smooth Muscle Actin

Applied Sciences, 2021
The aim was to determine the cytotoxicity of Khat (Catha edulis (Vahl) Forssk. ex Endl) on normal oral fibroblasts (NOFs) and SCC4 (squamous carcinoma cells) along with expression of α-smooth muscle actin (α-SMA) in fibroblasts.
Azeem Ul Yaqin Syed, Muhammad A. Ahmed, Eman I. AlSagob, Mansour Al-Askar, Abdulrahman M. AlMubarak, Rizwan Jouhar, Abdul R. Ahmed, Sameer A. Mokeem, Nada Aldahiyan, Fahim Vohra, Tariq Abduljabbar   +10 more
doaj   +1 more source

Spatial and temporal changes in extracellular elastin and laminin distribution during lung alveolar development [PDF]

, 2018
Lung alveolarization requires precise coordination of cell growth with extracellular matrix (ECM) synthesis and deposition. The role of extracellular matrices in alveogenesis is not fully understood, because prior knowledge is largely extrapolated from ...
Chen, Hui, Fernandez, G. Esteban, Krenitsky, Daria, Li, Nan, Luo, Yongfeng, Mecham, Robert P., Moats, Rex, Pryhuber, Gloria S., Shi, Wei, Warburton, David   +9 more
core   +2 more sources

Role of Fibroblasts and Myofibroblasts on the Pathogenesis and Treatment of Pelvic Organ Prolapse

Biomolecules, 2022
Pelvic organ prolapse (POP) is a multifactorial connective tissue disorder caused by damage to the supportive structures of the pelvic floor, leading to the descent of pelvic organs in the vagina.
Zeliha Guler, Jan Paul Roovers
doaj   +1 more source

Role of cellular senescence and NOX4-mediated oxidative stress in systemic sclerosis pathogenesis. [PDF]

, 2015
Systemic sclerosis (SSc) is a systemic autoimmune disease characterized by progressive fibrosis of skin and numerous internal organs and a severe fibroproliferative vasculopathy resulting frequently in severe disability and high mortality.
A Diazdeleon, A Dooley, A Erol, A Freund, A Gabrielli, A Gabrielli, A Gabrielli, A MacIntyre, A Salminen, A Servettaz, A Siani, A Sturrock, A Volpe, A Volpe, A Yoshizaki, AN Lyle, AZ Debbi, B Eckes, B Laleu, CB Harley, CD Bondi, CM Arlett, CM Stein, D Gvaramia, D Muñoz-Espin, D Muñoz-Espin, D Volonte, DE Furst, DF Murrell, E Rosato, E Savas, E Sikora, E Tourkina, E Tufvesson, ER Jarman, F Boin, F Gaggini, F Galdo Del, F Galdo Del, F Jiang, F Ogawa, F Ogawa, F Ogawa, F Tarhan, G Bai, G Simonini, GL Erre, GL Erre, H Sumimoto, H Xia, I Ben-Porath, I Cucoranu, I Montorfano, J Avouac, J Campisi, J El-Benna, J Goronzy, J Varga, JA Kim, JD Lambeth, JD Morrow, JF Passos, JF Passos, JH Chen, JL Barnes, JL Cracowski, JL Cracowski, JM Deursen van, JP Coppe, K Bedard, K Shimizu, KM Holmström, L Hayflick, L Hayflick, L Hecker, L Hecker, L Serrander, LL Song, M Böhm, M Chilosi, M Collado, M Elhai, M Geiszt, M Matucci-Cerinic, M Muller, M Schieber, M Storer, MD Mayes, MP Steele, MY Armanios, N Amara, N Duerrschmidt, N Manickam, N Sampson, O Babalola, P Cipriani, P Sambo, P Sambo, P Sambo, P Shivshankar, PS Tsou, Q Chen, QM Chen, R Salama, S Altenhöfer, S Bhattacharyya, S Parrinello, S Svegliati, Sergio A. Jimenez, SJ An, SK Parapuram, Sonsoles Piera-Velazquez, SR Datla, T Aoyama, T Finkel, T Kawahara, T Kuilman, T Ohtsuka, T Tchkonia, TK Kim, TR Katsumoto, VG Gorgoulis, VI Dumit, VJ Thannickal, WK Marut, WL Shen, X Duan, XM Wang, Y Allanore, Y Allanore, YH Paik   +130 more
core   +2 more sources