Results 41 to 50 of about 73,741 (198)
Generation of spheroids from human primary myofibroblasts: an experimental system to study myofibroblasts deactivation [PDF]
, 2017 Fibroblasts represent a heterogeneous cell population, that in adult body maintains the homeostasis of the extracellular matrix (ECM) and can acquire an immunoregulatory phenotype.
Ruocco, Maria Rosaria +7 more
core +1 more source
The types of hepatic myofibroblasts contributing to liver fibrosis of different etiologies.
Frontiers in Pharmacology, 2014 Liver fibrosis results from dysregulation of normal wound healing, inflammation, activation of myofibroblasts and deposition of extracellular matrix (ECM). Chronic liver injury causes death of hepatocytes and formation of apoptotic bodies, which in turn,
Jun eXu +8 more
doaj +1 more source
, 2023 COVID-19 has an extensive impact on Homo sapiens globally. Patients with COVID-19 are at an increased risk of developing pulmonary fibrosis. A previous study identified that myofibroblasts could be derived from pulmonary endothelial lineage cells as an ...
Xiuju Wu +3 more
core +1 more source
SRM Journal of Research in Dental Sciences, 2014 Introduction: Oral submucous fibrosis (OSMF) is a chronic debilitating disease and a premalignant condition of the oral cavity characterized by generalized submucosal fibrosis with a multifactorial etiology.
Teena Philip +5 more
doaj +1 more source
Fibrocytes: A Critical Review and Practical Guide
Frontiers in Immunology, 2021 Fibrocytes are hematopoietic-derived cells that directly contribute to tissue fibrosis by producing collagen following injury, during disease, and with aging.
James W. Reinhardt +3 more
doaj +1 more source
Origin of myofibroblasts in liver fibrosis [PDF]
, 2012 Most chronic liver diseases of all etiologies result in progressive liver fibrosis. Myofibroblasts produce the extracellular matrix, including type I collagen, which constitutes the fibrous scar in liver fibrosis.
T. Kisseleva +31 more
core +1 more source
Exclusive expression of KANK4 promotes myofibroblast mobility in keloid tissues
Scientific ReportsKeloids are characterized by abnormal wound healing with excessive accumulation of extracellular matrix. Myofibroblasts are the primary contributor to extracellular matrix secretion, playing an essential role in the wound healing process.
Mayumi Oishi +10 more
doaj +1 more source
eLife, 2018 Pdgfra-expressing (Pdgfra+) cells have been implicated as progenitors in many mesenchymal tissues. To determine lineage potential, we generated PdgfrartTA knockin mice using CRISPR/Cas9.
Rongbo Li +5 more
doaj +1 more source
Multicentric myofibroblastic sarcoma [PDF]
BMJ Case Reports, 2014 We report a case of synchronous, multicentric low-grade myofibroblastic sarcoma presenting in a 62-year-old man. He initially presented with inflammatory symmetric polyarthritis and adhesive capsulitis of his shoulder and hips bilaterally and did not respond to a trial of disease modifying antirheumatic drugs.
Mihir Dilip, Wechalekar +4 more
openaire +2 more sources
Myofibroblasts in schistosomal portal fibrosis of man.
, 1999 Myofibroblasts, cells with intermediate features between smooth muscle cells and fibroblasts, have been described as an important cellular component of schistosomal portal fibrosis. The origin, distribution and fate of myofibroblasts were investigated by
Fernandes, André L. M +8 more
core +3 more sources