Results 31 to 40 of about 61,389 (261)

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

FEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

Exclusive expression of KANK4 promotes myofibroblast mobility in keloid tissues

Scientific Reports
Keloids are characterized by abnormal wound healing with excessive accumulation of extracellular matrix. Myofibroblasts are the primary contributor to extracellular matrix secretion, playing an essential role in the wound healing process.
Mayumi Oishi, Keiko Shinjo, Keisuke Takanari, Ayako Muraoka, Miho M. Suzuki, Miki Kanbe, Shinichi Higuchi, Katsumi Ebisawa, Kazunobu Hashikawa, Yuzuru Kamei, Yutaka Kondo   +10 more
doaj   +1 more source

Immunohistochemical evaluation of myofibroblasts using alpha-smooth muscle actin in oral submucous fibrosis

SRM Journal of Research in Dental Sciences, 2014
Introduction: Oral submucous fibrosis (OSMF) is a chronic debilitating disease and a premalignant condition of the oral cavity characterized by generalized submucosal fibrosis with a multifactorial etiology.
Teena Philip, T Dinesh Kumar, K Rajkumar, K Raghavendhar Karthik, N Priyadharsini, A Ramesh Kumar   +5 more
doaj   +1 more source

Inflammatory Myofibroblastic Tumour

European Journal of Case Reports in Internal Medicine, 2020
Inflammatory myofibroblastic tumour (IMT) is a rare mesenchymal tumour. It is usually benign but may behave as a malignant tumour with multiple recurrences and metastases. We present the case of a young woman with weight loss associated with diffuse abdominal pain, who was shown to have a large pancreatic mass.
Pimentel Duarte, Pedro, Sousa, Rafaela, Chaves, Mariana, Amaral, Natacha, Lourenço, César   +4 more
openaire   +3 more sources

Strain‐Programmable Luminescent Adhesive Patch With Tartrazine‐Mediated Optical Skin Clearing for Photochemical Tissue Bonding

Advanced Functional Materials, EarlyView.
We propose a suture‐complementary approach that integrates optical skin clearing with a strain‐programmable luminescent adhesive patch. Hyaluronic acid promotes transdermal delivery of tartrazine to improve optical clearing and stabilizes its interaction with a photosensitizer. Optical clearing increases the penetration depth of visible light into skin,
Seong‐Jong Kim, Kyungjoo Jo, Kwanghyeon Park, Jun Hee Kim, Jong Hyeong Cho, Inhoo Choi, Sei Kwang Hahn   +6 more
wiley   +1 more source

A Systematic Study of GelMA‐Carbopol Bioinks for High‐Fidelity Extrusion 3D Bioprinting at Physiological Temperatures

Advanced Healthcare Materials, EarlyView.
Gonzalez Martinez and collaborators develop a strategy to formulate high performance GelMA‐based bioinks with low solids contents. The resulting bioinks enable 3D bioprinting at 37 °C of high‐fidelity structures with tunable mechanical properties that support high cell viability and function.
David A. González‐Martínez, Aidee V. Arizpe Tafoya, Eduardo González‐Martínez, Mabel Barreiro Carpio, Laura Daniela Serrano Andrade, Christopher T. N. Chow, Mohammadhossein Dabaghi, Jeremy A. Hirota, Jose M. Moran‐Mirabal   +8 more
wiley   +1 more source

Dedifferentiated early postnatal lung myofibroblasts redifferentiate in adult disease

Frontiers in Cell and Developmental Biology
Alveolarization ensures sufficient lung surface area for gas exchange, and during bulk alveolarization in mice (postnatal day [P] 4.5–14.5), alpha-smooth muscle actin (SMA)+ myofibroblasts accumulate, secrete elastin, and lay down alveolar septum. Herein,
Rachana R. Chandran, Rachana R. Chandran, Rachana R. Chandran, Taylor S. Adams, Inamul Kabir, Inamul Kabir, Eunate Gallardo-Vara, Eunate Gallardo-Vara, Naftali Kaminski, Brigitte N. Gomperts, Brigitte N. Gomperts, Brigitte N. Gomperts, Brigitte N. Gomperts, Brigitte N. Gomperts, Daniel M. Greif, Daniel M. Greif   +15 more
doaj   +1 more source

Extrusion Bioprinting for Wound Healing: Innovations in Functionalized Bioinks and Bioprinting Technology

Advanced Materials Technologies, EarlyView.
Extrusion‐based bioprinting (EBB) has emerged as a versatile biofabrication platform capable of precisely depositing bioinks composed of biomaterials, cells, and bioactive agents to generate patient‐specific, biomimetic skin constructs. This paper presents a state‐of‐the‐art and forward‐looking overview of EBB for wound healing, encompassing printing ...
Hien‐Phuong Le, Anh Tuan Trong Tran, Ammara Waheed, Tran Thanh Tung, Dusan Losic   +4 more
wiley   +1 more source

Capillarized Liver Sinusoidal Endothelial Cells Undergo Partial Endothelial-Mesenchymal Transition to Actively Deposit Sinusoidal ECM in Liver Fibrosis

Frontiers in Cell and Developmental Biology, 2021
Tissue-specific endothelial cells are more than simply a barrier lining capillaries and are proved to be capable of remarkable plasticity to become active collagen matrix-producing myofibroblasts (MFs) in solid organs with fibrosis.
Bai Ruan, Bai Ruan, Bai Ruan, Juan-Li Duan, Hao Xu, Kai-Shan Tao, Hua Han, Hua Han, Guo-Rui Dou, Lin Wang   +9 more
doaj   +1 more source

Multicentric myofibroblastic sarcoma [PDF]

BMJ Case Reports, 2014
We report a case of synchronous, multicentric low-grade myofibroblastic sarcoma presenting in a 62-year-old man. He initially presented with inflammatory symmetric polyarthritis and adhesive capsulitis of his shoulder and hips bilaterally and did not respond to a trial of disease modifying antirheumatic drugs.
Mihir Dilip, Wechalekar, Oliver, Ayres, Gelareh, Farshid, Mark, Clayer, Leslie G, Cleland   +4 more
openaire   +2 more sources