Results 31 to 40 of about 73,741 (198)

The role of myofibroblasts in orthodontic tooth movement

open access: yes口腔疾病防治, 2019
Myofibroblasts are fibroblasts with contractile function. As a contractile cell, myofibroblasts can regulate the function of normal organs in normal tissues.
PAN Xumeng, LIU Yi
doaj   +1 more source

Novel Therapies for the Treatment of Cardiac Fibrosis Following Myocardial Infarction

open access: yesBiomedicines, 2022
Cardiac fibrosis is a common pathological consequence of most myocardial diseases. It is associated with the excessive accumulation of extracellular matrix proteins as well as fibroblast differentiation into myofibroblasts in the cardiac interstitium ...
Kamila Raziyeva   +4 more
doaj   +1 more source

Human Galectins Induce Conversion of Dermal Fibroblasts into Myofibroblasts and Production of Extracellular Matrix: Potential Application in Tissue Engineering and Wound Repair [PDF]

open access: yes, 2011
Members of the galectin family of endogenous lectins are potent adhesion/growth-regulatory effectors. Their multi-functionality opens possibilities for their use in bioapplications. We studied whether human galectins induce the conversion of human dermal
Lacina, Lukas   +21 more
core   +1 more source

Myofibroblasts and polyploid cells in the conjunctival surface after allogeneic hematopoietic stem cell transplantation [PDF]

open access: yes, 2011
Allogeneic hematopoietic stem cell transplantation (allo-HSCT) is a potentially curative treatment modality for hematological malignancies, such as leukemia and lymphoma. However, a major complication of the procedure is that the immune effector cells in
Hallberg, David
core   +1 more source

Myofibroblast dedifferentiation proceeds via distinct transcriptomic and phenotypic transitions

open access: yesJCI Insight, 2021
Myofibroblasts are the major cellular source of collagen, and their accumulation — via differentiation from fibroblasts and resistance to apoptosis — is a hallmark of tissue fibrosis.
Sean M. Fortier   +5 more
doaj   +1 more source

The Yin and Yang of Mesenchymal Cells in the Corneal Stromal Fibrosis Response to Injury: The Cornea as a Model of Fibrosis in Other Organs

open access: yesBiomolecules, 2022
Mesenchymal cells (keratocytes, corneal fibroblasts, and myofibroblasts), as well as mesenchymal progenitor bone marrow-derived fibrocytes, are the major cellular contributors to stromal fibrosis after injury to the cornea.
Steven E. Wilson
doaj   +1 more source

Cytoglobin as a Marker of Hepatic Stellate Cell-derived Myofibroblasts

open access: yesFrontiers in Physiology, 2015
Myofibroblasts play important roles in inflammation, fibrosis and tumorigenesis in chronically inflamed liver. Liver myofibroblasts originate from hepatic stellate cells, portal fibroblasts or mesothelial cells, and they are localized in and around ...
Norifumi eKawada
doaj   +1 more source

Hyaluronidase pharmacological properties and clinical application in ophthalmology

open access: yesСибирский научный медицинский журнал, 2020
Corneal diseases are the fourth leading cause of blindness in the world, accounting for approximately 5 % of cases. Existing methods of treatment in more than 30 % of cases do not have a full therapeutic effect and when the process is stopped, they end ...
V. E. Zabanova   +2 more
doaj   +1 more source

Giant Intramuscular Nodular Fasciitis Masquerading as Soft Tissue Sarcoma with Neural Involvement - A Case Report [PDF]

open access: yesJournal of Clinical and Diagnostic Research, 2016
Nodular Fasciitis (NF) is described as a benign reactive proliferation of myofibroblasts that occurs predominantly in the subcutaneous location. Most commonly presents as rapidly growing swelling in the young adults, with usual size of less than 4cm and
Anandhi Amaranathan   +3 more
doaj   +1 more source

Cytotoxic Influence of Khat (Catha edulis (Vahl) Forssk. ex Endl) on Oral Fibroblasts, Squamous Carcinoma Cells, and Expression of α Smooth Muscle Actin

open access: yesApplied Sciences, 2021
The aim was to determine the cytotoxicity of Khat (Catha edulis (Vahl) Forssk. ex Endl) on normal oral fibroblasts (NOFs) and SCC4 (squamous carcinoma cells) along with expression of α-smooth muscle actin (α-SMA) in fibroblasts.
Azeem Ul Yaqin Syed   +10 more
doaj   +1 more source

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