Results 261 to 270 of about 53,888 (279)
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Dysregulated Myogenesis in Rhabdomyosarcoma
2018Rhabdomyosarcoma is a mesenchymal malignancy associated with the skeletal muscle lineage and is also the most common pediatric soft tissue cancer. Between the two pediatric subtypes, embryonal and alveolar rhabdomyosarcoma, the alveolar subtype is generally more aggressive and high-risk.
Denis C. Guttridge, Peter Y. Yu
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Myogenesis and muscle regeneration
Histochemistry and Cell Biology, 2012Skeletal muscle has received much attention with regard to developmental origin, control of cell differentiation and regeneration. In this article, early landmarks in skeletal muscle research are reviewed and recent findings on myogenesis are addressed with particular focus on novel regulatory molecules including miRNAs, as well as on the topographical
Faisal Yusuf, Beate Brand-Saberi
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Ciba Foundation symposium, 1992
The first striated muscle to form during mouse embryogenesis is the heart followed by skeletal muscle which is derived from the somites. The expression of genes encoding muscle structural proteins and myogenic regulatory sequences of the MyoD1 family has been examined using 35S-labelled riboprobes.
Gary E. Lyons +3 more
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The first striated muscle to form during mouse embryogenesis is the heart followed by skeletal muscle which is derived from the somites. The expression of genes encoding muscle structural proteins and myogenic regulatory sequences of the MyoD1 family has been examined using 35S-labelled riboprobes.
Gary E. Lyons +3 more
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Myogenesis on microcarrier cultures
Cell Biology International Reports, 1983The capacity of embryonic chick myoblasts to grow in vitro on DEAE-cellulose microcarriers (MC) has been investigated biochemically and morphologically. The cells attached to the MC, replicated and fused to form elongated myotubes. These myotubes synthesized muscle-specific proteins, such as creatine kinase (CK) and acetylcholine receptors (AChR), and ...
Asher Shainberg +4 more
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Myogenesis in the Genomics Era
Journal of Molecular Biology, 2015Skeletal myogenesis is the process of formation of the muscles that enable movement and breathing. Muscles form after the fate determination and differentiation of precursor cells. Being an extraordinarily complex process, myogenesis is regulated at multiple levels, and transcriptional regulation naturally plays a big part in the making of muscle.
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MyoD and the transcriptional control of myogenesis
Seminars in Cell & Developmental Biology, 2005The basic helix-loop-helix myogenic regulatory factors MyoD, Myf5, myogenin and MRF4 have critical roles in skeletal muscle development. Together with the Mef2 proteins and E proteins, these transcription factors are responsible for coordinating muscle-specific gene expression in the developing embryo.
Berkes, Charlotte A. +1 more
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POU homeodomain genes and myogenesis
Developmental Genetics, 1996We show that members of the POU homeodomain family are among the transcription factors expressed in developing mouse skeletal muscle. From a cDNA library prepared from fetal muscle mRNA, we cloned a cDNA identical to that of Brn-4, a POU class II gene previously cloned from neural tissues. In limb muscle, we found that Brn-4 mRNA expression was highest
Jeffrey Boone Miller, Janice A. Dominov
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Effect of a tumour promoter on myogenesis
Nature, 1977EVIDENCE that viruses and chemical carcinogens alter the ongoing synthetic programme of cells has been presented1,2. Chondroblasts and melanoblasts transformed with a temperature-sensitive Rous sarcoma virus cease synthesising the chondroblast-unique sulphated proteoglycan and melanin, respectively3.
Robert A. Cohen +4 more
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2013
Skeletal muscle cell differentiation, also known as myogenesis, is a complex process that directs proliferating myoblasts to differentiate into mature myotubes which are eventually organized into myofibers. Myogenesis involves a series of regulatory events that occur at both transcriptional and post-transcriptional levels.
Leonidas A. Phylactou +2 more
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Skeletal muscle cell differentiation, also known as myogenesis, is a complex process that directs proliferating myoblasts to differentiate into mature myotubes which are eventually organized into myofibers. Myogenesis involves a series of regulatory events that occur at both transcriptional and post-transcriptional levels.
Leonidas A. Phylactou +2 more
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Chapter 2 Myogenesis in the Mouse Embryo
1997Publisher Summary In recent years, molecular biologists have become increasingly interested in the process of myogenesis in vivo . Molecular tools are now available to distinguish among the products of related genes as muscles mature. The striking property of myogenic conversion exhibited in vitro by the MyoD family provides an opening to the ...
Margaret Buckingham +2 more
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