Results 111 to 120 of about 114,428 (345)

The mechanism of autooxidation of myoglobin.

Journal of Biological Chemistry, 1993
Time courses for the autooxidation of native and mutant sperm whale and pig myoglobins were measured at 37 degrees C in the presence of catalase and superoxide dismutase. In sperm whale myoglobin, His64(E7) was replaced with Gln, Gly, Ala, Val, Thr, Leu, and Phe; Val68(E11) was replaced with Ala, Ile, Leu, and Phe; Leu29(B10) was replaced with Ala, Val,
John S. Olson, Stephen J. Smerdon, Eileen W. Singleton, R E Brantley, Anthony J. Wilkinson   +4 more
openaire   +3 more sources

Non‐destructive quantification of egg yolk ratio using visible–near‐infrared hyperspectral imaging, machine learning and explainable AI

Journal of the Science of Food and Agriculture, EarlyView.
Abstract BACKGROUND Accurate, non‐destructive quantification of egg yolk ratio holds considerable significance for the food industry, nutritional assessment and egg grading. Conventional approaches are limited by destructive testing and insufficient throughput for commercial applications.
Md Wadud Ahmed, Jason Lee Emmert, Mohammed Kamruzzaman   +2 more
wiley   +1 more source

Elevated plasma myoglobin level is closely associated with type 2 diabetic kidney disease

Journal of Diabetes
Background Diabetic kidney disease (DKD) is the most frequent complication in patients with type 2 diabetes mellitus (T2DM). It causes a chronic and progressive decline in kidney function, and ultimately patients require renal replacement therapy.
Lin Yang, Yan Shen, Wenxiao Li, Bingbing Zha, Wenjun Xu, Heyuan Ding   +5 more
doaj   +1 more source

Trends of popularity of cardiac biomarkers: Insights from Google Trends

Emergency Care Journal, 2018
This study was aimed at assessing the trend of worldwide popularity, thus likely reflecting usage, of conventional cardiac biomarkers, including cardiac troponins, myoglobin and creatine kinase MB (CK-MB).
Giuseppe Lippi, Camilla Mattiuzzi, Gianfranco Cervellin   +2 more
doaj   +1 more source

Self‐Coacervation of Oligo(ethylene glycol) and Oligo(2‐ethyl‐2‐oxazoline)‐Based Double Hydrophilic Brush Block Copolymers in Aqueous Solution

Macromolecular Rapid Communications, EarlyView.
Here, the formation of double hydrophilic brush block copolymer‐based simple coacervates is presented. The system phase separates into polymer‐enriched droplets at elevated concentrations. The addition of guest polymers and biomacromolecules shows a distinct partitioning behaviour.
Niamh Bayliss, Matilde Concilio, Alexander Plucinski, Gokhan Yilmaz, C. Remzi Becer, Bernhard V. K. J. Schmidt   +5 more
wiley   +1 more source

Review of centrifugal liquid-liquid chromatography using aqueous two-phase solvent (ATPS) systems: Its scale-up and prospects for the future production of high-value biologics [PDF]

, 2007
The future challenges in bioprocessing include developing new downstream processes for the purification and manufacture of the protein based medicines of the future to relieve the predicted bottleneck being produced by increasingly high titres from ...
Sutherland, I A
core  

The Dynamic Transition of Protein Hydration Water [PDF]

, 2010
Thin layers of water on biomolecular and other nanostructured surfaces can be supercooled to temperatures not accessible with bulk water. Chen et al. [PNAS 103, 9012 (2006)] suggested that anomalies near 220 K observed by quasi-elastic neutron scattering
Appavou, M. -S., Busch, S., Doster, W., Gaspar, A. M., Scheer, H., Wuttke, J.   +5 more
core   +2 more sources

Proteomic Profiling Informs Mechanisms of Esophageal Adenocarcinoma Inhibition by Cranberry Proanthocyanidins

Molecular Nutrition &Food Research, EarlyView.
In this study we utilized proteomic profiling to investigate mechanisms linked to the cancer‐inhibitory effect of cranberry proanthocyanidins (CPACs) on reflux‐induced esophageal adenocarcinoma in a rat model. The results indicate that CPAC inhibits cancer through targeting multiple hallmarks of cancer known to be dysregulated in progression to ...
Yun Zhang, Michelle Lee, Erika de Jesus, Katherine Weh, Connor Howard, Henriette Remmer, Amy B. Howell, Laura A. Kresty   +7 more
wiley   +1 more source

Plasmonic ELISA for Sensitive Detection of Disease Biomarkers with a Smart Phone-Based Reader

Nanoscale Research Letters, 2018
Serum myoglobin is one of the earliest markers for the diagnosis of acute myocardial infarction. It is, therefore, critical to develop a point-of-care testing technology for myoglobin detection. In this work, we reported a sensitive plasmonic immunoassay-
Quanli Yang, Ruitian Cai, Wei Xiao, Zengfeng Wu, Xia Liu, Yan Xu, Miaomiao Xu, Hui Zhong, Guodong Sun, Qihui Liu, Qiangqiang Fu, Junjian Xiang   +11 more
doaj   +1 more source

A Phase 1, Double‐Blind, Placebo‐Controlled Trial of Sevasemten (EDG‐5506), a Selective Modulator of Fast Skeletal Muscle Contraction, in Healthy Volunteers and Adults With Becker Muscular Dystrophy

Muscle &Nerve, EarlyView.
ABSTRACT Introduction/Aims Sevasemten (EDG‐5506) is an orally administered, investigational small molecule that selectively modulates fast muscle fiber contraction by inhibiting fast myosin ATPase. This study assessed the safety, tolerability, and pharmacokinetics (PK)/pharmacodynamics (PD) of sevasemten in healthy adult volunteers (HVs) and adults ...
Joanne Donovan, Jeffrey A. Silverman, Ben Barthel, Michael DuVall, Molly Madden, James MacDougall, Nicole Rempel Kilburn, Abby Bronson, Marc Evanchik, Gilad Gordon, Kevin Koch, Alan J Russell   +11 more
wiley   +1 more source