Results 101 to 110 of about 54,674 (269)

Harnessing Aggregation‐Induced Emission for Advanced Disease Diagnosis: Mechanisms, Strategies and Future Perspectives

Medicine Bulletin, EarlyView.
The figure was created in BioRender.com. ABSTRACT Accurate and early diagnosis remains a key challenge in modern disease management. Conventional diagnostic methods often suffer from limitations in sensitivity, spatial resolution, and practical usability.
Zizhuo Du, Li Song, Xingrui Chen, Jun Jing, Yingchen Wang, Yue Jiang, Jiahui Gao, Dan Li, Feiran Xie, Peihong Xiao, Ben Zhong Tang   +10 more
wiley   +1 more source

Clinical interpretation of cardiac troponin in athletes: From endurance exercise to exertional injury

PM&R, EarlyView.
Abstract Exertional heat illness (EHI) and exertional rhabdomyolysis (ER) are increasingly recognized causes of morbidity in competitive and tactical athletes. Cardiac troponin (cTn) elevation, traditionally viewed as a marker of myocardial necrosis, may also be seen in these settings and can create significant diagnostic and prognostic uncertainty ...
John‐Henry L. Dean, Jeffrey C. Leggit, M. Alaric Franzos   +2 more
wiley   +1 more source

Plant responses to iron nutrition with emphasis on the underutilized crop tef (Eragrostis tef): A review

PLANTS, PEOPLE, PLANET, EarlyView.
Iron (Fe) deficiency limits the physical health, cognitive development, and economic output of billions of people globally, especially children and productive‐age women. Tef is an underutilized and stress‐resilient crop, which is becoming popular for its grains containing high bioavailable Fe and has the potential to mitigate Fe deficiency.
Muhammad Numan, David Remington, Ayalew Ligaba‐Osena   +2 more
wiley   +1 more source

Kidney REPLACEment therapies in patients with acute kidney injury and RHABDOmyolysis (ReplaceRhabdo): a pilot trial

BMC Nephrology
Background Rhabdomyolysis is frequently associated with acute kidney injury (AKI). Due to the nephrotoxic properties of myoglobin, its rapid removal is relevant.
Lorenz Weidhase, Antonia Borrmann, Anja Willenberg, Meinhard Mende, Christina Scharf-Janßen, Sirak Petros, Jonathan de Fallois   +6 more
doaj   +1 more source

Rapid myoglobin aggregation through glucosamine-induced α-dicarbonyl formation [PDF]

, 2015
The extent of glycation and conformational changes of horse myoglobin (Mb) upon glycation with N-acetyl-glucosamine (GlcNAc), glucose (Glc) and glucosamine (GlcN) were investigated.
Hrynets, Yuliya, Betti, Mirko, Ndagijimana, Maurice   +2 more
core   +1 more source

The Histidine 382 Residue Influences the Thermal Stability and Binding Propensity of the E2 Domain of Amyloid Precursor Protein

Proteins: Structure, Function, and Bioinformatics, EarlyView.
ABSTRACT The E2 domain of amyloid precursor protein (APP_E2) plays a central role in the protein's function. We reinvestigate how the missense mutation, ΔH382L, affects the domain's thermal stability and ligand binding propensity through differential scanning fluorometry.
Sphamandla Ndlovu, Candice Ngubane, Zamaxasibe Nxele, Raymond Hewer, Alexandré Delport   +4 more
wiley   +1 more source

The impact of saliva collection and processing methods on CRP, IgE, and Myoglobin immunoassays [PDF]

, 2012
UNLABELLED: BACKGROUND: Owing to its ease of collection, saliva is potentially the sample of choice in diagnosis. Salivary biomolecules have provided a porthole in surveying a person's health and well-being.
Campbell, Jennifer-Leigh, Cooper-White, Justin, Jennifer-Leigh Campbell, Goce Dimeski, Chamindie Punyadeera, Punyadeera, Chamindie, Roslinda Mohamed, Mohamed, Roslinda, Jennifer‐Leigh Campbell, Justin Cooper-White, Dimeski, Goce, Justin Cooper‐White   +11 more
core   +1 more source

Quantitative Imaging of Human Hemoglobin Binding to Staphylococcus aureus With Single‐Molecule Resolution

Small, EarlyView.
Single‐molecule localization microscopy is exploited to quantify the number of hemoglobin copies bound to specific receptors on S. aureus wall. This quantification supports the design of a photoactive derivative of hemoglobin able to photo‐inactivate S.
Pietro Delcanale, Andrea Mussini, Òscar Gulías, Montserrat Agut, Melissa Berni, Stefano Pongolini, Stefano Bruno, Alessandro Casnati, Santi Nonell, Cristiano Viappiani, Stefania Abbruzzetti   +10 more
wiley   +1 more source

Electrochemical and Biological Evaluation of Patterned TiO2@TiC‐Nanowires for Bio‐Interface Electrode

Small, EarlyView.
This study introduces a room‐temperature process to fabricate patterned TiO2@TiC core–shell nanowires, merging the biocompatibility of TiO2‐NWs with the high conductivity of TiC. Through sputtering pressure and time modulation, the nanowires morphology and electrochemical properties are tuned, enabling enhanced capacitance, stability, and guided ...
Roaa Sait, Shofarul Wustoni, Nabeel Aslam, Camelia Florica, Andrea Diaz‐Gaxiola, Valentina‐Elena Musteata, Mohammed K. Drad, Stephen Ghandour, Georgian Melinte, Yaping Zhang, Mohammed Nejib Hedhili, Ahad Ali Syed, Menouer Saidani, Shahryar Khattak, Imed Eddine‐Gallouzi, Sahika Inal, Hala Aljawhari   +16 more
wiley   +1 more source

A Mechanistic Study of Myoglobin Nephrotoxicity [PDF]

, 2002
Myoglobin is an endogenous protein that can become nephrotoxic under certain conditions such as crush injuries, drug overdose, and seizures where prolonged contraction of muscle leads to cell death and leakage of myoglobin.
Minigh, Jennifer L.
core