Results 81 to 90 of about 87,524 (253)
Bifunctional Photocatalysts: Exploiting Proximity for Enhanced Reaction Performance
Chemistry – A European Journal, EarlyView.This review covers the application of the bifunctional approach to photocatalysis as a means to attain (enhanced) enantioselectivity, and, more in general, as a strategy to enhance the catalytic performance through an effective use of short‐lived reaction intermediates.
Luigi Dolcini +3 more
wiley +1 more source
Electron Transfer in Proteins [PDF]
, 1996 Electron-transfer (ET) reactions are key steps in a diverse array of biological transformations ranging from photosynthesis to aerobic respiration. A powerful theoretical formalism has been developed that describes ET rates in terms of two parameters ...
Gray, Harry B., Winkler, Jay R.
core +1 more source
Structure and Spectroscopy of Criegee Intermediates in Gas‐ and Aqueous Environments
Helvetica Chimica Acta, EarlyView.ABSTRACT The dynamics and spectroscopy of the small (H2COO) and large (CH3CHOO) Criegee intermediates (CIs) in the gas phase, inside/on water droplets, on amorphous solid water (ASW) and in bulk water are investigated using validated energy functions.
Cangtao Yin +2 more
wiley +1 more source
Clinicopathological spectrum of Acute Kidney Injury due to Myoglobin Cast Nephropathy
Academic Medicine & Surgery# Objective Myoglobin cast nephropathy is a serious yet potentially preventable cause of acute kidney injury (AKI), most commonly occurring secondary to severe rhabdomyolysis.
Hemant Kumar, Shivani Prashar
doaj +1 more source
Review of centrifugal liquid-liquid chromatography using aqueous two-phase solvent (ATPS) systems: Its scale-up and prospects for the future production of high-value biologics [PDF]
, 2007 The future challenges in bioprocessing include developing new downstream processes for the purification and manufacture of the protein based medicines of the future to relieve the predicted bottleneck being produced by increasingly high titres from ...
Sutherland, I A
core
Suppression of mitochondrial respiration through recruitment of p160 myb binding protein to PGC-1α : modulation by p38 MAPK [PDF]
, 2004 The transcriptional coactivator PPAR gamma coactivator 1 α (PGC-1α) is a key regulator of metabolic processes such as mitochondrial biogenesis and respiration in muscle and gluconeogenesis in liver. Reduced levels of PGC-1α in humans have been associated
Fan, M. +9 more
core +1 more source
Journal of the Chinese Chemical Society, EarlyView.While X‐ray crystallography has been the primary method for determining the structures of metalloproteins, cryoEM has taken over this role, illustrated by [4Fe4S]‐cluster containing proteins deposited in the Protein Data Bank. What will be the role for X‐ray crystallography as cryoEM and machine learning methods dominate the initial structural analysis?
Douglas C. Rees
wiley +1 more source
Ion Activation Methods for Top‐Down Proteomics
Mass Spectrometry Reviews, EarlyView.ABSTRACT Mass spectrometry (MS) has emerged as a premier method used to characterize the sequences of proteins. Top‐down proteomics aims to capture the multiple sources of structural diversity reflected in proteins, such as those that arise from alternative RNA splicing events or the addition of post‐translational modifications. Tandem MS (i.e., MS/MS)
Jada N. Walker, Jennifer S. Brodbelt
wiley +1 more source
Mass Spectrometry Reviews, EarlyView.ABSTRACT Top‐down proteomics (TDP) characterizes proteoforms in cells, tissues, and biofluids, in discovery mode and on a global scale, requiring analytical tools with high peak capacity for proteoform separation and high sensitivity for proteoform detection, given the extremely high proteoform complexity and wide proteoform concentration dynamic range.
Guijie Zhu +5 more
wiley +1 more source
Elevated plasma myoglobin level is closely associated with type 2 diabetic kidney disease
Journal of DiabetesBackground Diabetic kidney disease (DKD) is the most frequent complication in patients with type 2 diabetes mellitus (T2DM). It causes a chronic and progressive decline in kidney function, and ultimately patients require renal replacement therapy.
Lin Yang +5 more
doaj +1 more source