Results 131 to 140 of about 117,263 (356)

The Crystal Structure of Human Transport and Golgi Organization 2 Homolog (TANGO2) Protein Reveals an αββα‐Fold Arrangement

open access: yesProteins: Structure, Function, and Bioinformatics, EarlyView.
ABSTRACT Transport and Golgi Organization 2 Homolog (TANGO2) protein deficiency disorder (TDD) is a rare autosomal recessive disorder characterized by multi‐systemic abnormalities and significant phenotypic variability including neurodevelopmental delay, seizures, intermittent ataxia, hypothyroidism, rhabdomyolysis, life‐threatening metabolic ...
Anne Cooper   +6 more
wiley   +1 more source

Structural interpretation of the amino acid sequence of a second domain from the Artemia covalent polymer globin [PDF]

open access: yes, 1990
Artemia has a complex extracellular hemoglobin of Mr 260,000 comprising two globin chains (Mr 130,000) each of which is a polymer of eight covalently linked domains of Mr 16,000.
Alard, Philippe   +8 more
core   +1 more source

Acute kidney injury and iron metabolism: A narrative review focusing on pathophysiology and therapy

open access: yesSmart Molecules, EarlyView.
Schematic illustration of acute kidney injury and iron metabolism (By Figdraw). Image for iron metabolism, including uptake, storage, utilization, export: Reproduced with permission. Abstract Acute kidney injury (AKI) represents a substantial challenge to public health and is characterized by elevated occurrence and fatality rates.
Xinyu Tan   +4 more
wiley   +1 more source

Conformational Dependence of a Protein Kinase Phosphate Transfer Reaction

open access: yes, 2004
Atomic motions and energetics for a phosphate transfer reaction catalyzed by the cAMP-dependent protein kinase (PKA) are calculated by plane-wave density functional theory, starting from structures of proteins crystallized in both the reactant ...
Austin   +22 more
core   +2 more sources

Native Taylor/Non‐Taylor Dispersion–Mass Spectrometry (TNT‐MS) Allows Rapid Protein Desalting and Multiplexed, Label‐Free Ligand Screening

open access: yesSmall Methods, EarlyView.
Native mass spectrometry enables the label‐free study of noncovalent protein‐ligand complexes; however, it is incompatible with conventional molecular biology buffers. By exploiting the dependence of flow dynamics on the hydrodynamic radius, proteins are seperated, including protein‐ligand complexes, from non‐volatile salts and unbound small molecules ...
Jonathan Eisert   +10 more
wiley   +1 more source

Atypical presentation of pheochromocytoma as acute ischemic stroke and pulmonary embolism, a case report

open access: yesUroPrecision, EarlyView.
Abstract Background Pheochromocytoma is a rare catecholamine‐secreting tumor that often presents with symptoms such as hypertension, palpitations, and sweating due to excessive hormone production. In some cases, the catecholamine‐induced vasoconstriction and hypercoagulability associated with pheochromocytomas can lead to cerebrovascular accidents and ...
Mohannad N. AbuHaweeleh   +6 more
wiley   +1 more source

Red urine in a 68‐year‐old man with amyotrophic lateral sclerosis

open access: yes
Journal of General and Family Medicine, EarlyView.
Kento Furuya, Naoya Itoh
wiley   +1 more source

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