Results 11 to 20 of about 115,678 (349)

Admission serum myoglobin and the development of acute kidney injury after major trauma

Annals of Intensive Care, 2021
Background Myoglobin and creatine kinase (CK) are both established markers of muscle injury but their hospital admission values have never been compared to predict post-traumatic acute kidney injury (AKI).
Virginie Tarazona, Samy Figueiredo, Sophie Hamada, Jonas Pochard, Ryan W. Haines, John R. Prowle, Jacques Duranteau, Bernard Vigué, Anatole Harrois   +8 more
doaj   +2 more sources

Blood purification with a cytokine adsorber for the elimination of myoglobin in critically ill patients with severe rhabdomyolysis

Critical Care, 2021
Background Rhabdomyolysis is frequently occurring in critically ill patients, resulting in a high risk of acute kidney injury (AKI) and potentially permanent kidney damage due to increased myoglobin levels.
Christina Scharf, Uwe Liebchen, Michael Paal, Michael Irlbeck, Michael Zoller, Ines Schroeder   +5 more
doaj   +2 more sources

Myoglobin promotes macrophage polarization to M1 type and pyroptosis via the RIG-I/Caspase1/GSDMD signaling pathway in CS-AKI

Cell Death Discovery, 2022
Crush syndrome (CS) is a life-threatening illness in traffic accidents and earthquakes. Crush syndrome-induced acute kidney injury (CS-AKI) is considered to be mainly due to myoglobin (Mb) circulation and deposition after skeletal muscle ruptures and ...
Ning Li, Jiale Chen, Chenhao Geng, Xinyue Wang, Yuru Wang, Na Sun, Pengtao Wang, Lu Han, Zizheng Li, Haojun Fan, Shike Hou, Yanhua Gong   +11 more
doaj   +2 more sources

Species-Specificity in Myoglobin Oxygenation and Reduction Potential Properties

Meat and Muscle Biology, 2017
The objective was to compare oxygenation and reduction potential properties of bovine and porcine myoglobins in-vitro. Cyclic voltammetry and homology-based myoglobin modeling were used to determine the species-specific effects on myoglobin reduction ...
Rajasekhara Nerimetla, Sadagopan Krishnan, Suman Mazumder, Smita Mohanty, Gretchen G. Mafi, Deborah L. VanOverbeke, Ranjith Ramanathan   +6 more
doaj   +2 more sources

Myoglobin clearance with continuous veno-venous hemodialysis using high cutoff dialyzer versus continuous veno-venous hemodiafiltration using high-flux dialyzer: a prospective randomized controlled trial

Critical Care, 2020
Background Myoglobin clearance in acute kidney injury requiring renal replacement therapy is important because myoglobin has direct renal toxic effects.
Lorenz Weidhase, Jonathan de Fallois, Elena Haußig, Thorsten Kaiser, Meinhard Mende, Sirak Petros   +5 more
doaj   +2 more sources

Crosstalk between nitrite, myoglobin and reactive oxygen species to regulate vasodilation under hypoxia. [PDF]

PLoS ONE, 2014
The systemic response to decreasing oxygen levels is hypoxic vasodilation. While this mechanism has been known for more than a century, the underlying cellular events have remained incompletely understood.
Matthias Totzeck, Ulrike B Hendgen-Cotta, Malte Kelm, Tienush Rassaf   +3 more
doaj   +2 more sources

Electrochemical Aptasensor for Myoglobin-Specific Recognition Based on Porphyrin Functionalized Graphene-Conjugated Gold Nanocomposites

Sensors, 2016
In this work, a novel electrochemical aptasensor was developed for sensitive and selective detection of myoglobin based on meso-tetra (4-carboxyphenyl) porphyrin-functionalized graphene-conjugated gold nanoparticles (TCPP–Gr/AuNPs).
Guojuan Zhang, Zhiguang Liu, Li Wang, Yujing Guo   +3 more
doaj   +2 more sources

Serum myoglobin modulates kidney injury via inducing ferroptosis after exertional heatstroke

Journal of Translational Internal Medicine, 2023
Background and Objectives Myoglobin released by rhabdomyolysis (RM) is considered to be involved in pathogenesis of kidney disease caused by crush injury, but whether high level of serum myoglobin predisposes patients to acute kidney injury (AKI) and its
Y. Luan, E. Huang, Jia-jia Huang, Zhenjia Yang, Zhipeng Zhou, Yan Liu, Conglin Wang, Ming Wu   +7 more
semanticscholar   +1 more source

Successful Reduction of Creatine Kinase and Myoglobin Levels in Severe Rhabdomyolysis Using Extracorporeal Blood Purification (CytoSorb®)

Blood Purification, 2020
Rhabdomyolysis, if severe, can lead to acute kidney injury (AKI). Myoglobin is an iron and oxygen-binding protein that is freely filtered by the glomerulus.
Olcay Dilken, C. Ince, B. van der Hoven, Sjoerd Thijsse, Patricia Ormskerk, H. D. de Geus   +5 more
semanticscholar   +1 more source

Green synthesis as a simple and rapid route to protein modified magnetic nanoparticles for use in the development of a fluorometric molecularly imprinted polymer-based assay for detection of myoglobin

Nanotechnology, 2020
We have developed a low-cost molecularly imprinted polymer (MIP)-based fluorometric assay to directly quantify myoglobin in a biological sample. The assay uses a previously unreported method for the development of microwave-assisted rapid synthesis of ...
Mark V. Sullivan, William J Stockburn, P. Hawes, T. Mercer, S. Reddy   +4 more
semanticscholar   +1 more source