Results 11 to 20 of about 119,093 (354)

Neonatal hyper- and hypothyroidism alter the myoglobin gene expression program in adulthood [PDF]

open access: yesBrazilian Journal of Medical and Biological Research, 2014
Myoglobin acts as an oxygen store and a reactive oxygen species acceptor in muscles. We examined myoglobin mRNA in rat cardiac ventricle and skeletal muscles during the first 42 days of life and the impact of transient neonatal hypo- and hyperthyroidism ...
K. de Picoli Souza, M.T. Nunes
doaj   +3 more sources

Serum myoglobin modulates kidney injury via inducing ferroptosis after exertional heatstroke

open access: yesJournal of Translational Internal Medicine, 2023
Background and Objectives Myoglobin released by rhabdomyolysis (RM) is considered to be involved in pathogenesis of kidney disease caused by crush injury, but whether high level of serum myoglobin predisposes patients to acute kidney injury (AKI) and its
Y. Luan   +7 more
semanticscholar   +1 more source

Rapid and Effective Elimination of Myoglobin with CytoSorb® Hemoadsorber in Patients with Severe Rhabdomyolysis

open access: yesBlood Purification, 2023
Introduction: Rhabdomyolysis is characterized by destruction of muscle fibers by various causes and is diagnosed by increased creatine kinase concentrations in the blood. Myoglobin released into the blood may cause acute kidney injury. In this randomized
Frederic W Albrecht   +6 more
semanticscholar   +1 more source

Extracorporeal Removal of Myoglobin in Patients with Rhabdomyolysis and Acute Kidney Injury: Comparison of High and Medium Cut-Off Membrane and an Adsorber Cartridge

open access: yesBlood Purification, 2022
Introduction: The role of extracorporeal myoglobin removal in the treatment of rhabdomyolysis-associated severe acute kidney injury (AKI) is not yet fully established.
Alexander Jerman   +3 more
semanticscholar   +1 more source

Caffeine increases myoglobin expression via the cyclic AMP pathway in L6 myotubes

open access: yesPhysiological Reports, 2021
Myoglobin is an important regulator of muscle and whole‐body metabolism and exercise capacity. Caffeine, an activator of the calcium and cyclic AMP (cAMP)/protein kinase A (PKA) pathway, enhances glucose uptake, fat oxidation, and mitochondrial ...
Takumi Yokokawa   +2 more
doaj   +1 more source

Camel myoglobin [PDF]

open access: yesBiochemical Journal, 1966
1. Crystalline myoglobin was prepared from camel heart muscle. 2. A method was developed for the isolation of myoglobin that employs molecular-sieve chromatography. 3. Analytical chromatography of the camel myoglobin on a molecular-sieve column and on two types of ion-exchange columns gave in each case a single elution band, which accounted for better ...
E S, Awad, L, Kotite
openaire   +2 more sources

Case Report: Prevention of Rhabdomyolysis-Associated Acute Kidney Injury by Extracorporeal Blood Purification With Cytosorb®

open access: yesFrontiers in Pediatrics, 2022
Acute kidney injury (AKI) is a severe complication of rhabdomyolysis. The pathophysiology of rhabdomyolysis-associated AKI is complex, but myoglobin related damage plays a major role.
Simon Rauch   +7 more
doaj   +1 more source

“Rigid” structure is a key determinant for the low digestibility of myoglobin

open access: yesFood Chemistry: X, 2020
Myoglobin, a critical protein responsible for meat color, has been shown insusceptible to digestion. The underlying mechanism is not clear. The present study aimed to evaluate whether the structural properties of myoglobin are associated with its ...
Qian Li   +7 more
doaj   +1 more source

Label-Free, Highly Sensitive Electrochemical Aptasensors Using Polymer-Modified Reduced Graphene Oxide for Cardiac Biomarker Detection [PDF]

open access: yes, 2020
Acute myocardial infarction (AMI), also recognized as a ???heart attack,??? is one leading cause of death globally, and cardiac myoglobin (cMb), an important cardiac biomarker, is used for the early assessment of AMI.
Bhardwaj, Jyoti   +2 more
core   +1 more source

Successful Reduction of Creatine Kinase and Myoglobin Levels in Severe Rhabdomyolysis Using Extracorporeal Blood Purification (CytoSorb®)

open access: yesBlood Purification, 2020
Rhabdomyolysis, if severe, can lead to acute kidney injury (AKI). Myoglobin is an iron and oxygen-binding protein that is freely filtered by the glomerulus.
Olcay Dilken   +5 more
semanticscholar   +1 more source

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