Results 41 to 50 of about 1,633 (129)

Enhancing Meat Quality Through Dietary Fiber: Insights Into the Gut Microbiota‐Derived Short‐Chain Fatty Acids‐Muscle Axis

Animal Research and One Health, EarlyView.
Dietary fiber (DF) modulates meat quality through the gut‐muscle axis by reshaping gut microbiota, improving intestinal integrity, reducing inflammation, and regulating muscle metabolism. These mechanisms influence muscle fiber characteristics and post‐mortem biochemistry, thereby enhancing tenderness, juiciness, color, flavor, and nutritional value of
Zeshan Zulfiqar, Muhammad Arslan Asif, Layla Al‐Mitib, Nabeela Ashiq, Haojie Wang, Yalei Cui, Boshuai Liu, Shucheng Huang, Yinghua Shi   +8 more
wiley   +1 more source

Serum Myoglobin in Patients with Thyroid Dysfunction

Sultan Qaboos University Medical Journal, 2009
Objectives: To assess the pattern of change in serum myoglobin concentration in subjects with thyroid dysfunction. Methods: Serum samples were selected from 150 subjects with suspected thyroid disorder who were referred to the Royal Hospital, Muscat ...
Waad-Allah S Mula-Abed, Sawsan S Al-Sinani, Huda S Al-Hashmi   +2 more
doaj  

Anifrolumab Treatment Leads to Rapid Reduction in Urinary Biomarkers of Intrarenal Inflammation in Lupus Nephritis: Results From the Phase 2 Randomized Trial

Arthritis &Rheumatology, EarlyView.
Objective Lupus nephritis (LN) is one of the most severe manifestations of systemic lupus erythematosus (SLE) and is partially driven by type I interferon signaling. Anifrolumab, an approved treatment for patients with SLE, has been investigated in a phase 2 trial in patients with LN receiving standard therapy (TULIP‐LN, ClinicalTrials.gov identifier ...
Andrea Fava, Michelle Petri, Patrick G. Gavin, Eszter Csomor, Philip Z. Brohawn, Daniel Muthas, Adam Platt, Catharina Lindholm, Nicola Ferrari   +8 more
wiley   +1 more source

Site-Directed Mutagenesis of Myoglobin for Studies of Their Interaction with Iron(III) by Multi-Spectroscopic Techniques

Journal of Spectroscopy, 2013
In order to investigate how the amino acids on the surface of myoglobin molecule influence myoglobin's structure and function, a variety of spectroscopy techniques were applied in the study of the interaction between Fe(III) and myoglobin (wild type and ...
Qian Tang, Xiao-Jun Peng, Hong-Yu Cao, Yan-Jie Yang, Jing Ma, Jing-Yun Wang, Xue-Fang Zheng   +6 more
doaj   +1 more source

Interleukin‐2 Deprived State of Regulatory T cells and Their Recovery by Low‐Dose Interleukin‐2 in Patients With Inflammatory Myopathies

Arthritis &Rheumatology, EarlyView.
Objective Regeneration and expansion of Treg by low‐dose interleukin‐2 (IL‐2) therapy is considered a potential treatment strategy for a wide range of autoimmune diseases. To provide a pathophysiologically‐based rationale for low‐dose IL‐2 therapy, we investigated whether reversible defects in the Treg–IL‐2 axis emerge in inflammatory myopathies ...
Justus Ohmes, Luisa R. Monne, Sara Comdühr, Fynn Gerlach, Hanna Grasshoff, Alexander Dübbers, Antje Müller, Alexander Scheffold, Gabriela Riemekasten, Reza Akbarzadeh, Jens Y. Humrich   +10 more
wiley   +1 more source

Integrated Microfluidic Giant Magnetoresistance (GMR) Biosensor Platform for Magnetoresistive Immunoassay of Myoglobin

Biosensors
Acute myocardial infarction (AMI) is a rapidly progressing cardiovascular condition associated with high mortality. Myoglobin is an early biomarker of AMI; however, its detection using conventional methods is limited by complex workflows and low ...
Yikai Wang, Huaiyu Wang, Yunyun Zhang, Shuhui Cui, Fei Hu, Bo’an Li   +5 more
doaj   +1 more source

Enhanced Optical Sensitivity of Polyvinyl Alcohol–Reduced Graphene Oxide Electrospun Nanofiber Coated Etched Fiber Bragg Grating Sensor for Detection of Myoglobin a Cardiac Biomarker

Advanced Photonics Research, 2021
Etched fiber Bragg grating (eFBG) sensors have shown to be highly sensitive with the capability of giving accurate real‐time response to a variety of measurands such as pressure, gas, biomolecules, to name a few. These sensors have not shown their mettle
Kavitha B. Srinivasan, Vikram S. Raghavan, Munish Shorie, Priyanka Sabherwal, Sai S Gorthi, Sundarrajan Asokan, Ajay. K. Sood   +6 more
doaj   +1 more source

Acute toxicity of ADB‐CHMINACA ‐ a case series of patients with pronounced central nervous symptoms including the posterior reversible encephalopathic syndrome

British Journal of Clinical Pharmacology, EarlyView.
Aim This report presents a series of 16 patients who were admitted to the emergency department following confirmed intake of the potent synthetic cannabinoid ADB‐CHMINACA. Methods The cases are drawn from a prospective observational study following the recreational use of synthetic cannabinoids.
Maren Hermanns‐Clausen, Michaela Sommer, Annette Zschiesche, Verena Angerer, Martin Scheu, Florian Eyer, Johannes Nadler, Volker Auwärter   +7 more
wiley   +1 more source

Continuous Purification of mRNA Produced by In Vitro Transcription Using High Performance Countercurrent Membrane Purification

Biotechnology and Bioengineering, EarlyView.
ABSTRACT Messenger ribonucleic acid (mRNA) therapeutics produced by in vitro transcription must be purified to remove residual enzymes and free nucleotides. This study examines the use of high‐performance countercurrent membrane purification (HPCMP) for the purification of mRNA therapeutics based on differences in the rate of diffusion across ...
Ziqiao Wang, Amin Javidanbardan, Ali Behboudi, Andrew L. Zydney   +3 more
wiley   +1 more source

Nanoplastics: Methods, Exposure and Effects on Domestic, Farm and Wild Animals

Journal of Applied Toxicology, EarlyView.
ABSTRACT Nanoplastics (NPs) are synthetic polymer particles ranging in size from 1 nm to 1 μm that have been identified as a major concern for ecosystems and organisms due to their plethora of negative effects. The aim of this review is to provide a comprehensive overview of the knowledge relating to exposure and effects of NPs in domestic (i.e., farm ...
B. De Felice, M. Bertazzo, A. F. Tabaran, M. Parolini, R. P. Popa, A. Pintea, L. J. Spicer, A‐L. Nagy, F. Caloni   +8 more
wiley   +1 more source