Results 51 to 60 of about 1,633 (129)

Clinicopathological spectrum of Acute Kidney Injury due to Myoglobin Cast Nephropathy

Academic Medicine & Surgery
# Objective Myoglobin cast nephropathy is a serious yet potentially preventable cause of acute kidney injury (AKI), most commonly occurring secondary to severe rhabdomyolysis.
Hemant Kumar, Shivani Prashar
doaj   +1 more source

A Personal Perspective on Metalloprotein Structure and the Future of Macromolecular X‐Ray Crystallography

Journal of the Chinese Chemical Society, EarlyView.
While X‐ray crystallography has been the primary method for determining the structures of metalloproteins, cryoEM has taken over this role, illustrated by [4Fe4S]‐cluster containing proteins deposited in the Protein Data Bank. What will be the role for X‐ray crystallography as cryoEM and machine learning methods dominate the initial structural analysis?
Douglas C. Rees
wiley   +1 more source

Analytical and Workflow Performance of a High‐Throughput Chemiluminescent Immunoassay System in a Clinical Laboratory

Journal of Clinical Laboratory Analysis, EarlyView.
Analytical and operational performance evaluation of the DxI 9000 Access Immunoassay Analyzer in a clinical laboratory in Taiwan. ABSTRACT Background Increasing test volumes and shorter turnaround time (TAT) requirements, particularly in acute‐care settings, challenge clinical laboratories to maintain accurate immunoassay testing.
Chiung‐Tzu Hsiao, Chao‐Ching Liao, Yu‐Chang Chang, Hui‐Ju Chang, Tz‐Ya Huang, Jen‐Shiou Lin, Po‐Ren Hsueh   +6 more
wiley   +1 more source

Early prediction of acute kidney injury in traumatic and non‐traumatic rhabdomyolysis using an interpretable machine learning model: A multicenter study with external validation

Journal of Intelligent Medicine, EarlyView.
Abstract Acute kidney injury (AKI) is a common and severe complication of rhabdomyolysis (RM), and early risk stratification remains challenging because of its multifactorial and heterogeneous nature. We developed and externally validated an interpretable machine learning (ML) model for early prediction of AKI in RM across traumatic and non‐traumatic ...
Chunli Liu, Jie Shi, Fengjuan Wang, Liang Ma, Huangang Hu, Li Zhang, Jie Song, Heng Jin, Dingwei Yang, Xiaoqin Guo, Haojun Fan, Qi Lv   +11 more
wiley   +1 more source

Elevated plasma myoglobin level is closely associated with type 2 diabetic kidney disease

Journal of Diabetes
Background Diabetic kidney disease (DKD) is the most frequent complication in patients with type 2 diabetes mellitus (T2DM). It causes a chronic and progressive decline in kidney function, and ultimately patients require renal replacement therapy.
Lin Yang, Yan Shen, Wenxiao Li, Bingbing Zha, Wenjun Xu, Heyuan Ding   +5 more
doaj   +1 more source

Trends of popularity of cardiac biomarkers: Insights from Google Trends

Emergency Care Journal, 2018
This study was aimed at assessing the trend of worldwide popularity, thus likely reflecting usage, of conventional cardiac biomarkers, including cardiac troponins, myoglobin and creatine kinase MB (CK-MB).
Giuseppe Lippi, Camilla Mattiuzzi, Gianfranco Cervellin   +2 more
doaj   +1 more source

Quality‐driven reformulation of Plantago ovata enriched non‐fermented beef salami

Journal of the Science of Food and Agriculture, EarlyView.
Abstract BACKGROUND Plantago ovata (psyllium) is a hydrocolloid additive that is used widely in foods; however, meat applications of this bioactive ingredient are limited. This study evaluated the effects of 0% to 5% Plantago husk on non‐fermented beef salami during 60 days of storage. Proximate composition, physicochemical properties, texture profile,
Tulay Elal Mus, Tulay Ozcan, Gokce Keser, Tugce Necla Selvi, Figen Cetinkaya, Hakan Ustuner, Nursen Senturk   +6 more
wiley   +1 more source

Ion Activation Methods for Top‐Down Proteomics

Mass Spectrometry Reviews, EarlyView.
ABSTRACT Mass spectrometry (MS) has emerged as a premier method used to characterize the sequences of proteins. Top‐down proteomics aims to capture the multiple sources of structural diversity reflected in proteins, such as those that arise from alternative RNA splicing events or the addition of post‐translational modifications. Tandem MS (i.e., MS/MS)
Jada N. Walker, Jennifer S. Brodbelt
wiley   +1 more source

Plasmonic ELISA for Sensitive Detection of Disease Biomarkers with a Smart Phone-Based Reader

Nanoscale Research Letters, 2018
Serum myoglobin is one of the earliest markers for the diagnosis of acute myocardial infarction. It is, therefore, critical to develop a point-of-care testing technology for myoglobin detection. In this work, we reported a sensitive plasmonic immunoassay-
Quanli Yang, Ruitian Cai, Wei Xiao, Zengfeng Wu, Xia Liu, Yan Xu, Miaomiao Xu, Hui Zhong, Guodong Sun, Qihui Liu, Qiangqiang Fu, Junjian Xiang   +11 more
doaj   +1 more source

Recent Advances (2023–2025) of Capillary Electrophoresis‐Mass Spectrometry (CE‐MS) for Top‐Down Proteomics

Mass Spectrometry Reviews, EarlyView.
ABSTRACT Top‐down proteomics (TDP) characterizes proteoforms in cells, tissues, and biofluids, in discovery mode and on a global scale, requiring analytical tools with high peak capacity for proteoform separation and high sensitivity for proteoform detection, given the extremely high proteoform complexity and wide proteoform concentration dynamic range.
Guijie Zhu, David A. Alvarez Rodriguez, Noah Gould, Alexander R. Ivanov, Kevin Jooß, Liangliang Sun   +5 more
wiley   +1 more source