Results 41 to 50 of about 96,991 (291)

Implementation of Drug‐Induced Rhabdomyolysis and Acute Kidney Injury in Microphysiological System

Advanced Functional Materials, EarlyView.
A modular Muscle–Kidney proximal tubule‐on‐a‐chip integrates 3D skeletal muscle and renal proximal tubule tissues to model drug‐induced rhabdomyolysis and acute kidney injury. The coculture system enables dynamic tissue interaction, functional contraction monitoring, and quantification of nephrotoxicity, revealing drug side effect‐induced metabolic ...
Jaesang Kim, Zhuo Feng Lee, Gi‐Dong Sim, Sejoong Kim, Jessie S. Jeon   +4 more
wiley   +1 more source

Serum Myoglobin Is Associated With Postoperative Acute Kidney Injury in Stanford Type A Aortic Dissection

Frontiers in Medicine, 2022
BackgroundThe correlation between rhabdomyolysis and postoperative acute kidney injury has been reported in several surgical procedures. As a good predictor of rhabdomyolysis-related acute kidney injury, an elevated serum myoglobin level was often ...
Chen Yang, Peng Hou, Dongxu Wang, Zhenguo Wang, Weixun Duan, Jincheng Liu, Shiqiang Yu, Feng Fu, Zhenxiao Jin   +8 more
doaj   +1 more source

Towards Quantitative Classification of Folded Proteins in Terms of Elementary Functions

, 2010
A comparative classification scheme provides a good basis for several approaches to understand proteins, including prediction of relations between their structure and biological function. But it remains a challenge to combine a classification scheme that
Andrei Krokhotin, Antti J. Niemi, O. M. Becker, Shuangwei Hu, Xubiao Peng   +4 more
core   +1 more source

Myoglobin function reassessed [PDF]

Journal of Experimental Biology, 2003
SUMMARYThe heart and those striated muscles that contract for long periods, having available almost limitless oxygen, operate in sustained steady states of low sarcoplasmic oxygen pressure that resist change in response to changing muscle work or oxygen supply. Most of the oxygen pressure drop from the erythrocyte to the mitochondrion occurs across the
Jonathan B, Wittenberg, Beatrice A, Wittenberg   +1 more
openaire   +2 more sources

Oxygen and ROS Delivery for Infected Wound Healing and Future Prospects

Advanced Healthcare Materials, EarlyView.
Bacterial infection is a major driver of delayed wound healing and postsurgical readmissions; with rising antibiotic resistance, solid peroxide–releasing biomaterials offer sustained delivery of ROS/O2 for antimicrobial control and microenvironmental modulation.
Ayden Watt, Chably Rachella, Charlotte Jaloux, Joshua Vorstenbosch, Adam Hart, Michael Tanzer, Geraldine Merle, Jake Barralet   +7 more
wiley   +1 more source

Solvent-induced organization: A physical model of folding myoglobin

, 1994
The essential features of the in vitro refolding of myoglobin are expressed in a solvable physical model. Alpha helices are taken as the fundamental collective coordinates of the system, while the refolding is assumed to be mainly driven by solvent ...
Acampora, Allen, Anfinsen, Arnold, Arutyunyan, Bashford, Ben-Naim, Callaway, Cantor, Chothia, Christenson, Claesson, Cohen, Creighton, David J. E. Callaway, Dickerson, Dill, Eisenberg, Evans, Franks, Gardiner, Griko, Gruenewald, Hughson, Hughson, Hughson, Israelachvili, Jaenicke, Jennings, Jones, Jorgensen, Kuczera, Kuwajima, Levinthal, Levitt, Levitt, Levitt, McCammon, Nicholls, Nishikawa, Nozaki, Pangali, Pangali, Podgornik, Potter, Pratt, Privalov, Ptitsyn, Ptitsyn, Puett, Rao, Saito, Shaknovich, Sharp, Shen, Shin, Shin, Smith, Stillinger, Stouten, Tanford, Waltho, Warshel, Watson, Wax, Wolfenden, Zimmerman   +66 more
core   +2 more sources

Probabilistic classification of acute myocardial infarction from multiple cardiac markers [PDF]

, 2008
Logistic regression and Gaussian mixture model (GMM) classifiers have been trained to estimate the probability of acute myocardial infarction (AMI) in patients based upon the concentrations of a panel of cardiac markers.
C Bishop, F Dombal de, F Fesmire, F Fesmire, George W. Irwin, H Selker, J Ellenuis, J Habbema, J Habbema, J Habbema, J Hanley, J Hilden, J Hilden, John V. Lamont, L Goldman, L Goldman, M Pozen, Paul C. Wilson, Robert F. Harrison, T Groth, W Tierney   +20 more
core   +1 more source

Smart REASSURED Sensors via Machine‐Augmented Printable On‐Paper Arrays

Advanced Sensor Research, EarlyView.
This perspective highlights the emerging role of pattern‐recognition, printable on‐paper sensor arrays for intelligent PoC diagnostics. It discusses how paper's inherent limitations can be overcome through surface modification and scalable printing, and how machine‐learning analysis of cross‐reactive arrays enables multiplexed, low‐cost, and REASSURED ...
Naimeh Naseri, Saba Ranjbar
wiley   +1 more source

Isolation and Characterization of Chelonia mydas Myoglobin

Hayati Journal of Biosciences, 2012
Green sea turtle – Chelonia mydas is a lung respiration animal that is able to dive and stay uder sea water for hours without needing to surface for oxygen.
MOHAMAD SADIKIN, RINI PUSPITANINGRUM, SEPTELIA INAWATI WANANDI, RONDANG ROEMIATI SOEGIANTO   +3 more
doaj   +3 more sources

MYOGLOBIN CONTENT IN CARDIAC MUSCLE OF PHYSICAL EXERCISE INDUCED RAT (Rattus norvegicus)

Simbiosis: Journal of Biological Sciences, 2017
The research was aimed to analyzing the impact of 7 days arobic exercise in elevating rat cardiac muscle myoglobin. Experimental in vivo study on 20 male Wistar rat induced by 20m/ min treadmill aerobic exercise for 1, 3 and 7 days. Research was done in
Sri Rahayu, Rini Puspitaningrum, Mohammad Sadikin   +2 more
doaj