Results 41 to 50 of about 117,263 (356)

Femtosecond X-ray emission study of the spin cross-over dynamics in haem proteins

, 2020
In haemoglobin (consisting of four globular myoglobin-like subunits), the change from the low-spin (LS) hexacoordinated haem to the high spin (HS) pentacoordinated domed form upon ligand detachment and the reverse process upon ligand binding, represent ...
Bacellar, Camila, Bressler, Christian, Budarz, James, Cannelli, Oliviero, Chergui, Majed, Galler, Andreas, Gawelda, Wojciech, Higashimura, Chika, Ito, Hironori, Ito, Terumasa, Katayama, Tetsuo, Keane, Theo, Khakhulin, Dmitry, Kinschel, Dominik, Kudo, Shotaro, Kurahashi, Naoya, Lima, Frederico A., Mancini, Giulia F., Milne, Christopher J., Misawa, Kazuhiko, Nishitani, Junichi, Obara, Yuki, Penfold, Thomas, Rouxel, Jeremy R., Schulz, Sebastian, Sorokin, Boris, Suzuki, Toshinori, Yabashi, Makina, Zalden, Peter   +28 more
core   +1 more source

Engineering tyrosine-based electron flow pathways in proteins: The case of aplysia myoglobin [PDF]

, 2012
Tyrosine residues can act as redox cofactors that provide an electron transfer ("hole-hopping") route that enhances the rate of ferryl heme iron reduction by externally added reductants, for example, ascorbate.
Alayash A. I., Alayash A. I., Aubert C., Bolognesi M., Brandon J. Reeder, Chris E. Cooper, Dimitri A. Svistunenko, Egmond M. R., Ekberg M., Ekberg M., Gray H. B., Holt S., Lardinois O. M., McLeod L. L., Michael T. Wilson, Moore K. P., Natanson C., Nilges M. J., Peisach J., Reece S. Y., Reeder B. J., Reeder B. J., Reeder B. J., Reeder B. J., Reeder B. J., Reeder B. J., Reeder B. J., Rogers M. S., Rova U., Rova U., Seyedsayamdost M. R., Shih C., Silaghi-Dumitrescu R., Stubbe J., Svistunenko D. A., Svistunenko D. A., Svistunenko D. A., Thompson M. K., Wilbur D. J., Yee C. S.   +39 more
core   +1 more source

Myoglobin expression: early induction and subsequent modulation of myoglobin and myoglobin mRNA during myogenesis.

Molecular and Cellular Biology, 1986
We showed that myoglobin gene transcription and the appearance of myoglobin occur very early in myogenesis, in both humans and mice. In contrast to the contractile protein genes, there is a subsequent increase of 50- to 100-fold in myoglobin mRNA and protein levels during later muscle development.
Y H Edwards, H Isenberg, A J Jeffreys, P A Weller, M Price   +4 more
openaire   +4 more sources

Comparison of Creatine Kinase Activity and Myoglobin Blood Level in Acute Myocardial Infarction Patients

Biomolecules & Biomedicine, 2008
The aim of this prospective study was to evaluate and compare the relative increase of serum myoglobin level and total creatine kinase(CK) activity in acute myocardial infarction (AMI) patients (n=36). We measured serial changes in total CK activity and 
Sabaheta Hasić, Radivoj Jadrić, Emina Kiseljaković, Jovan Radovanović, Mira Winterhalter-Jadrić   +4 more
doaj   +1 more source

Solvent-induced organization: A physical model of folding myoglobin

, 1994
The essential features of the in vitro refolding of myoglobin are expressed in a solvable physical model. Alpha helices are taken as the fundamental collective coordinates of the system, while the refolding is assumed to be mainly driven by solvent ...
Acampora, Allen, Anfinsen, Arnold, Arutyunyan, Bashford, Ben-Naim, Callaway, Cantor, Chothia, Christenson, Claesson, Cohen, Creighton, David J. E. Callaway, Dickerson, Dill, Eisenberg, Evans, Franks, Gardiner, Griko, Gruenewald, Hughson, Hughson, Hughson, Israelachvili, Jaenicke, Jennings, Jones, Jorgensen, Kuczera, Kuwajima, Levinthal, Levitt, Levitt, Levitt, McCammon, Nicholls, Nishikawa, Nozaki, Pangali, Pangali, Podgornik, Potter, Pratt, Privalov, Ptitsyn, Ptitsyn, Puett, Rao, Saito, Shaknovich, Sharp, Shen, Shin, Shin, Smith, Stillinger, Stouten, Tanford, Waltho, Warshel, Watson, Wax, Wolfenden, Zimmerman   +66 more
core   +2 more sources

Myoglobin modulates the Hippo pathway to promote cardiomyocyte differentiation

iScience
Summary: The endogenous mechanisms that propagate cardiomyocyte differentiation and prevent de-differentiation remain unclear. While the expression of the heme protein myoglobin increases by over 50% during cardiomyocyte differentiation, a role for ...
Krithika Rao, Elizabeth Rochon, Anuradha Singh, Rajaganapathi Jagannathan, Zishan Peng, Haris Mansoor, Bing Wang, Mousumi Moulik, Manling Zhang, Anita Saraf, Paola Corti, Sruti Shiva   +11 more
doaj   +1 more source

Estimated glomerular filtration rate is a poor predictor of the concentration of middle molecular weight uremic solutes in chronic kidney disease [PDF]

, 2012
Background: Uremic solute concentration increases as Glomerular Filtration Rate (GFR) declines. Weak associations were demonstrated between estimated GFR (eGFR) and the concentrations of several small water-soluble and protein-bound uremic solutes ...
Barreto, Daniela V, Barreto, Fellype C, Eloot, Sunny, Glorieux, Griet, Lemke, Horst D, Lenglet, Aurélie, Liabeuf, Sophie, Massy, Ziad A, Neirynck, Nathalie, Vanholder, Raymond   +9 more
core   +5 more sources

Serum Myoglobin Is Associated With Postoperative Acute Kidney Injury in Stanford Type A Aortic Dissection

Frontiers in Medicine, 2022
BackgroundThe correlation between rhabdomyolysis and postoperative acute kidney injury has been reported in several surgical procedures. As a good predictor of rhabdomyolysis-related acute kidney injury, an elevated serum myoglobin level was often ...
Chen Yang, Peng Hou, Dongxu Wang, Zhenguo Wang, Weixun Duan, Jincheng Liu, Shiqiang Yu, Feng Fu, Zhenxiao Jin   +8 more
doaj   +1 more source

Spectral characterisation of red pigment in Italian-type dry-cured ham. Increasing lipophilicity druing processing and maturation [PDF]

, 2003
Spectroscopic studies of Parma ham during processing revealed a gradual transformation of muscle myoglobin, initiated by salting and continuing during ageing.
Adamsen, Christina E., Møller, Jens K.S., Skibsted, Leif H.   +2 more
core  

Biosensors for cardiac biomarkers detection: a review [PDF]

, 2012
The cardiovascular disease (CVD) is considered as a major threat to global health. Therefore, there is a growing demand for a range of portable, rapid and low cost biosensing devices for the detection of CVD.
Gurbuz, Yasar, Gürbüz, Yaşar, Kolkar Mohammed, Javed Hussain Niazi, Qureshi, Anjum   +3 more
core   +1 more source