Results 11 to 20 of about 61,167 (344)

A single-cell atlas of the myometrium in human parturition

open access: yesJCI Insight, 2022
Parturition is a well-orchestrated process characterized by increased uterine contractility, cervical ripening, and activation of the chorioamniotic membranes; yet, the transition from a quiescent to a contractile myometrium heralds the onset of labor ...
R. Pique-Regi   +18 more
semanticscholar   +1 more source

Integrated Proteotranscriptomics of Human Myometrium in Labor Landscape Reveals the Increased Molecular Associated With Inflammation Under Hypoxia Stress

open access: yesFrontiers in Immunology, 2021
During labor, a variety of coordinated physiological and biochemical events cause the myometrium to transition from a quiescent to contractile state; the molecular mechanisms responsible for this transition, however, remain unclear.
Lina Chen   +6 more
semanticscholar   +1 more source

Prostacyclin Synthesis and Prostacyclin Receptor Expression in the Porcine Myometrium: Prostacyclin Potential to Regulate Fatty Acid Transporters, Cytokines and Contractility-Related Factors

open access: yesAnimals, 2022
Although prostacyclin (PGI2) has been well described as a regulator of smooth muscle activity, limited data are available concerning its role in the myometrium of pigs.
Agnieszka Blitek   +2 more
doaj   +1 more source

Modulating the mechanokinetics of spontaneous contractions of the myometrium of rats using calix[4]arene C-90 – plasma membrane calcium ATPase inhibitor

open access: yesБіологічні студії, 2021
Introduction. Plasma membrane calcium ATPase is a constitutive structure of cells that functions as a high affinity system of releasing Са2+ ions from the cytoplasm and ensures a long-term maintenance of the basal concentration of these cations in the ...
O. V. Tsymbalyuk
doaj   +1 more source

Comparison of the myometrial transcriptome from singleton and twin pregnancies by RNA-Seq.

open access: yesPLoS ONE, 2020
Preterm birth is recognized as the primary cause of infant mortality worldwide. Twin pregnancies are significantly more at risk of preterm birth than singleton pregnancies.
Sarah Arrowsmith   +2 more
doaj   +1 more source

Evidence for the expression of vasorin in the human female reproductive tissues

open access: yesGynecological Endocrinology, 2023
Objective: To investigate the expression and localization of Vasorin (Vasn) in human female reproductive system. Methods: The presence of Vasorin was evaluated by RT-PCR and immunoblotting analyses in patient-derived endometrial, myometrial and granulosa
Marilena Taggi   +7 more
doaj   +1 more source

Total tissue lactate dehydrogenase activity in endometrial carcinoma [PDF]

open access: yes, 2008
Lactate dehydrogenase (LDH) is essential for continuous glycolysis necessary for accelerated tumor growth. The aim of this study was to reconsider if assay of total tissue activity of this enzyme could be useful as marker for endometrial carcinoma (EC ...
Abramić, Marija   +4 more
core   +1 more source

Expression of ATP-sensitive potassium channels in human pregnant myometrium

open access: yesReproductive Biology and Endocrinology, 2011
Background Potassium channels play critical roles in the regulation of cell membrane potential, which is central to the excitability of myometrium. The ATP-sensitive potassium (KATP) channel is one of the most abundant potassium channels in myometrium ...
Hui Ning   +7 more
doaj   +1 more source

Corticotropin-releasing hormone interacts with interleukin-1 to regulate prostaglandin H synthase-2 expression in human myometrium during pregnancy and labor [PDF]

open access: yes, 2013
Context: The onset of labor appears to involve the activation of myometrial inflammatory pathways, and transcription factors such as nuclear factor-κB (NF-κB) control expression of the contraction-associated proteins required to induce a procontractile ...
Bari, Muhammad F.   +4 more
core   +1 more source

The onset of labor alters corticotropin-releasing hormone type 1 receptor variant expression in human myometrium : putative role of interleukin-1ß [PDF]

open access: yes, 2007
CRH targets the human myometrium during pregnancy. The efficiency of CRH actions is determined by expression of functional receptors (CRH-R), which are dynamically regulated.
Grammatopoulos, Dimitris   +6 more
core   +1 more source

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