Regulators of G protein signalling proteins in the human myometrium [PDF]
, 2009 The contractile state of the human myometrium is controlled by extracellular signals that promote relaxation or contraction. Many of these signals function through G proteincoupled receptors at the cell surface, stimulating heterotrimeric G proteins and ...
Ladds, Graham +4 more
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The onset of labor alters corticotropin-releasing hormone type 1 receptor variant expression in human myometrium : putative role of interleukin-1ß [PDF]
, 2007 CRH targets the human myometrium during pregnancy. The efficiency of CRH actions is determined by expression of functional receptors (CRH-R), which are dynamically regulated.
Gu, Mei +6 more
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Identification of a novel corticotropin-releasing hormone type 1 beta-Like receptor variant lacking exon 13 in human pregnant myometrium regulated by estradiol-17 beta and progesterone [PDF]
, 2010 Two types of CRH receptors mediate the diverse biological functions of CRH and CRH-related peptides. The type 1 CRH-R (CRH-R1) is extensively targeted by pre-mRNA splicing mechanisms that give rise to multiple mRNA splice variants.
Jing Chen +13 more
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Disseminated Tuberculosis Presenting as Tubo-Ovarian Mass
Journal of Nepal Medical Association, 2004 Postmenopausal tuberculosis with the involvement of myometrium is rare. A 54 years old lady who presented with painful abdominal mass and urinary retention was diagnosed as a case of dissiminated tuberculosis involving myometrium and the adenexa.
Punam Prasad Bhadani, SP Shah, S Babu
doaj +1 more source
Corticotropin-releasing hormone interacts with interleukin-1 to regulate prostaglandin H synthase-2 expression in human myometrium during pregnancy and labor [PDF]
, 2013 Context: The onset of labor appears to involve the activation of myometrial inflammatory pathways, and transcription factors such as nuclear factor-κB (NF-κB) control expression of the contraction-associated proteins required to induce a procontractile ...
Grammatopoulos, Dimitris +5 more
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Evidence for the expression of vasorin in the human female reproductive tissues
Gynecological Endocrinology, 2023 Objective: To investigate the expression and localization of Vasorin (Vasn) in human female reproductive system. Methods: The presence of Vasorin was evaluated by RT-PCR and immunoblotting analyses in patient-derived endometrial, myometrial and granulosa
Marilena Taggi +7 more
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Spatial heterogeneity enhances and modulates excitability in a mathematical model of the myometrium [PDF]
, 2013 The muscular layer of the uterus (myometrium) undergoes profound changes in global excitability prior to parturition. Here, a mathematical model of the myocyte network is developed to investigate the hypothesis that spatial heterogeneity is essential to ...
Conor Mccloskey +13 more
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The contribution of Kv7 channels to pregnant mouse and human myometrial contractility. [PDF]
, 2011 Premature birth accounts for approximately 75% of neonatal mortality and morbidity in the developed world. Despite this, methods for identifying and treating women at risk of preterm labour are limited and many women still present in preterm labour ...
Pierce, SL +9 more
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Fine spatiotemporal activity in contracting myometrium revealed by motion-corrected calcium imaging [PDF]
, 2014 Successful childbirth depends on the occurrence of precisely coordinated uterine contractions during labour. Calcium indicator fluorescence imaging is one of the main techniques for investigating the mechanisms governing this physiological process and ...
Loftus, Fiona C. +2 more
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Influence of smooth muscle contractility by inhibition of crac channels activity
European Pharmaceutical Journal, 2017 The present in vitro study was focused on the differences in expression and activity of calcium release-activated calcium (CRAC) channels of human term-pregnant and non-pregnant myometrium. The expression of Orai1 protein, as a functional subunit of CRAC
Kocmálová M., Kazimierová I.
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