Inhibition of Na(+),K(+)-ATPase and activation of myosin ATPase by calix[4]arene C-107 cause stimulation of isolated smooth muscle contractile activity [PDF]
The discovery of compounds that might modify myometrial contractility is an important area of researches. In our previous experiments, we found that some representatives of macrocyclic compounds family – calix[4]arenes – can modify the enzymatic and ...
T. O. Veklich +6 more
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Uterine Isthmocele—A Frequently Overlooked Complication of Cesarean Sections
Uterine isthmocele or uterine niche is a late complication of cesarean deliveries and causes chronic pelvic pain, menorrhagia or postmenstrual spotting, and infertility.
R. Rupa, Suchana Kushvaha, K. Venkatesh
doaj +1 more source
In the experiment the influence of inflammation on neuropeptide Y (NPY) receptor subtype 1 (Y1Rs) and 2 (Y2Rs) expression pattern in the gilt myometrium and NPY effect alone or with Y1Rs and Y2Rs antagonists on contractility of an inflamed uterus were ...
Barbara Jana +2 more
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Although prostacyclin (PGI2) has been well described as a regulator of smooth muscle activity, limited data are available concerning its role in the myometrium of pigs.
Agnieszka Blitek +2 more
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Clinical and morphological features of the cesarean scar pregnancy
The features of timely diagnosis and possible risks of the cesarean scar pregnancy are demonstrated on the example of a clinical case. This article presents analysis of pregnancy and childbirth of patient Sh., who was in the Obstetrics Department of the
N.P. Honcharuk +4 more
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Regulators of G protein signalling proteins in the human myometrium [PDF]
The contractile state of the human myometrium is controlled by extracellular signals that promote relaxation or contraction. Many of these signals function through G proteincoupled receptors at the cell surface, stimulating heterotrimeric G proteins and ...
Abramow-Newerly +52 more
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Expression of ATP-sensitive potassium channels in human pregnant myometrium
Background Potassium channels play critical roles in the regulation of cell membrane potential, which is central to the excitability of myometrium. The ATP-sensitive potassium (KATP) channel is one of the most abundant potassium channels in myometrium ...
Hui Ning +7 more
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Comparison of the myometrial transcriptome from singleton and twin pregnancies by RNA-Seq.
Preterm birth is recognized as the primary cause of infant mortality worldwide. Twin pregnancies are significantly more at risk of preterm birth than singleton pregnancies.
Sarah Arrowsmith +2 more
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Na+-leak channel, non-selective (NALCN) regulates myometrial excitability and facilitates successful parturition [PDF]
Background/Aims: Uterine contractility is controlled by electrical signals generated by myometrial smooth muscle cells. Because aberrant electrical signaling may cause inefficient uterine contractions and poor reproductive outcomes, there is great ...
Amazu, Chinwendu +8 more
core +3 more sources
Ca(2+)-dependent regulation of the Ca(2+) concentration in the myometrium mitochondria. I. Trifluoperazine effects on mitochondria membranes polarization and [Ca(2+)](m) [PDF]
Са2+-dependent regulation of Ca2+ exchange in mitochondria is carried out with participation of calmodulin. We have shown previously that calmodulin antagonists reduced the level of mitochondrial membrane polarization and induced increase of the ionized ...
L. G. Babich +3 more
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