Single-Cell RNA Sequencing of Retina Reveals Nna1 Upregulation in Myopic Diabetic Retinopathy as a Protective Factor Against Diabetic Damage. [PDF]
This study investigates a schematic overview of the mechanistic pathways. The relationship between myopia and DR has long been of clinical interest. In diabetic mice, Nna1 expression is downregulated, whereas in diabetic mice with FDM, Nna1 expression is upregulated–particularly in Müller cells–accompanied by decreased vascular endothelial growth ...
Xie L, Cai Y, Chen B, Li B, Zou J, Xu H.
europepmc +2 more sources
Long-term follow-up of myopic choroidal neovascularization treated with ranibizumab [PDF]
PURPOSE: To evaluate the long-term safety and efficacy of intravitreal ranibizumab in the treatment of myopic choroidal neovascularization (CNV). METHODS: Three-year retrospective, nonrandomized, interventional case series.
Cachulo, ML +6 more
core +1 more source
Clinical disorders affecting mesopic vision [PDF]
Vision in the mesopic range is affected by a number of inherited and acquired clinical disorders. We review these conditions and summarize the historical background, describing the clinical characteristics alongside the genetic basis and molecular ...
Abramowicz M. +100 more
core +1 more source
Attenuation of choroidal tickness in patients with Alzheimer disease: evidence from an Italian prospective study [PDF]
INTRODUCTION: To compare the 12-month choroidal thickness (CT) change between Alzheimer disease (AD) patients and normal subjects. METHODS: In this prospective, observational study, 39 patients with a diagnosis of mild to moderate AD and 39 age ...
Campanelli, A +7 more
core +1 more source
Peripheral retina degeneration in patients who are candidates for refractive surgery [PDF]
Purpose: To verify, in myopic individuals who are candidates for refractive surgery, the prevalence of different types of peripheral degenerative lesions of the retina, according to the type of myopia.
Allemann, Norma +4 more
core +2 more sources
Vitrectomy in high myopia: a narrative review
Pathologic myopia is associated with degenerative changes of the globe, especially at the posterior pole. Eyes affected by pathologic myopia have higher odds to undergo posterior segment surgery and, in those eyes, vitreoretinal surgery is challenging ...
Michele Coppola +4 more
doaj +1 more source
Macular hole is characterized by a full-thickness defect of the retinal layers in the center of the fovea and is an important cause of central vision loss.
Murat Yüksel +2 more
doaj +1 more source
A review of the role of ultrasound biomicroscopy in glaucoma associated with rare diseases of the anterior segment [PDF]
Ultrasound biomicroscopy is a non-invasive imaging technique, which allows high-resolution evaluation of the anatomical features of the anterior segment of the eye regardless of optical media transparency.
Abdolrahimzadeh, B +5 more
core +2 more sources
Association of High Myopia with Crystallin Beta A4 (CRYBA4) Gene Polymorphisms in the Linkage-Identified MYP6 Locus [PDF]
Background: Myopia is the most common ocular disorder worldwide and imposes tremendous burden on the society. It is a complex disease. The MYP6 locus at 22 q12 is of particular interest because many studies have detected linkage signals at this interval.
Fung, WY +4 more
core +1 more source
Issues of Supplemental Support in Pediatric Ophthalmology
The ophthalmologist often raises the issues about using of various vitamins, trace elements and other nutrients for the prevention and treatment of the different ocular diseases at their practice.
I. A. Gndoyan
doaj +1 more source

