Distinctive Mechanisms and Patterns of Exudative Versus Tractional Intraretinal Cystoid Spaces as Seen With Multimodal Imaging. [PDF]
PurposeTo determine clear-cut distinctions between tractional and exudative intraretinal cystoid spaces subtypes.DesignRetrospective, multicenter, observational case series.MethodsA cohort of patients diagnosed with intraretinal cystoid spaces and imaged
Au, Adrian+9 more
core
Outcomes of cataract surgery at a referral center
Purpose: To report the outcomes of cataract surgery at a large referral eye hospital and to identify factors associated with less than excellent visual outcomes.
Seyed-Farzad Mohammadi+7 more
doaj +1 more source
Abstract Compared to traditional small molecule drugs, monoclonal antibodies (mAbs) often display more complex pharmacokinetic (PK) and pharmacodynamic (PD) properties that may be impacted by disease‐specific factors. For mAbs in non‐oncology indications, where the same drug might be used for conditions involving different organ systems and/or having ...
Sherouk M. Tawfik, Fei Tang
wiley +1 more source
Long-term follow-up of myopic choroidal neovascularization treated with ranibizumab [PDF]
PURPOSE: To evaluate the long-term safety and efficacy of intravitreal ranibizumab in the treatment of myopic choroidal neovascularization (CNV). METHODS: Three-year retrospective, nonrandomized, interventional case series.
Cachulo, ML+6 more
core +1 more source
Optic Disc Pallor in Parkinson's Disease: A UK Biobank Study
Abstract Background Recent studies have suggested that retinal changes measured with optical coherence tomography are detectable in early Parkinson's disease (PD), highlighting the potential of ophthalmic biomarkers for diagnosis and monitoring. Objective We set out to investigate the relationship between optic disc pallor measured in fundoscopy images
Samuel Gibbon+3 more
wiley +1 more source
Quantitative assessment of the long-term effect of photodynamic therapy in patients with pathologic myopia [PDF]
Background: In patients with classic subfoveal choroidal neovascularization (CNV) secondary to pathologic myopia (PM), photodynamic therapy (PDT) has been shown to stabilize the visual acuity.
Jochmann, Claudia+3 more
core
Pathological myopia classification with simultaneous lesion segmentation using deep learning [PDF]
This investigation reports on the results of convolutional neural networks developed for the recently introduced PathologicAL Myopia (PALM) dataset, which consists of 1200 fundus images. We propose a new Optic Nerve Head (ONH)-based prediction enhancement for the segmentation of atrophy and fovea.
arxiv
Microwave Chirality Imaging for the Early Diagnosis of Neurological Degenerative Diseases [PDF]
We propose a system to visualize the chirality of the protein in brains, which would be helpful to diagnose early neurological degenerative diseases in vivo. These neurological degenerative diseases often occur along with some mark proteins. By nanoparticle instilling and metamaterial technique, the chiral effect of the mark proteins is assumed to be ...
arxiv
Where the Weather Comes From [PDF]
When Andreas Malm observed that “not even the weather belongs fully to the moment,” he was looking forward from 2016, considering the cumulative impact of present emissions on “generations not yet born.” The reverse is also true: present storms have ...
Vanek, Morgan
core +1 more source
A Genome-Wide Association Analysis Identified a Novel Susceptible Locus for Pathological Myopia at 11q24.1 [PDF]
Myopia is one of the most common ocular disorders worldwide. Pathological myopia, also called high myopia, comprises 1% to 5% of the general population and is one of the leading causes of legal blindness in developed countries.
Gotoh, Norimoto+13 more
core +2 more sources