Results 131 to 140 of about 161,523 (294)
Advanced Science, EarlyView.Rapamycin alleviates heart failure via TFEB and CaMKII pathways in Syntaxin 12/13 deficient models. Stx12 deficiency causes heart failure via impaired iron trafficking to mitochondria, reducing respiratory complexes and sarcoplasmic reticulum Ca2+‐ATPase (SERCA).
Run‐Zhou Yang +12 more
wiley +1 more source
Advanced Science, EarlyView.Schematic overview showing that forkhead box O6, opposite strand (Foxo6os) acts as a “scaffold”, directly binding myosin‐binding protein‐C (MYBPC3) and recruiting protein kinase C (PKC‐α) to mediate site‐specific phosphorylation of MYBPC3. This post‐translational modification supports cardiac contraction by regulating L‐type Ca2+ channels, especially ...
Jie Sheng +9 more
wiley +1 more source
Water‐Soluble Molecular Wires for Membrane Potential Imaging
Angewandte Chemie, EarlyView.Fully water‐soluble fluorescent rosamine‐based amphiphilic molecular wires were developed for imaging membrane potentials. The performance of the probes was evaluated in single cardiomyocytes, murine pituitary gland, and islets of Langerhans.
Mirna El Khatib +9 more
wiley +2 more sources
Hydrogen ion buffers and enzymatic activity: Myosin B adenosinetriphosphatase [PDF]
, 1968 Richard A. Murphy, P.G. Koss
openalex +1 more source
Interfacial Stress Regulates Plasticity and Drug Resistance at the Breast Cancer‐Host Interface
Advanced Science, EarlyView.Drop‐on‐demand printing is used to replicate the spatial compartmentalization of the breast cancer‐host interface. Hydrogel confinement affects phenotypic changes in cells at the spheroid interface that drives a two‐fold increase in chemotherapeutic resistance compared to control unconfined spheroids.
Bram G. Soliman +4 more
wiley +1 more source
Decoding Myosin-3 mutational hotspots: Linking deleterious variants to Duchenne muscular dystrophy severity and psychiatric comorbidities. [PDF]
PLoS OneHakami MA +3 more
europepmc +1 more source
Hydrostatic pressure effects on rabbit and echinoderm myosin ATPase [PDF]
, 1969 Karl F. Guthe
openalex +1 more source
Advanced Science, EarlyView.A next‐generation cytosine base editor (zTadCBE) and other variants are developed by combining the high‐efficiency (TadCBEa) and low‐indel (TadCBEMax) architectures, followed by the introduction of zebrafish‐optimized mutations (V82S, Q154R) in the TadA domain.
Wei Qin +7 more
wiley +1 more source
The Twisting and Untwisting of Actin and Tropomyosin Filaments Are Involved in the Molecular Mechanisms of Muscle Contraction, and Their Disruption Can Result in Muscle Disorders. [PDF]
Int J Mol SciBorovikov YS +4 more
europepmc +1 more source