Results 261 to 270 of about 159,767 (320)

Atomic Force Microscopy Reveals Differences In Mechanical Properties Linked To Cortical Structure In Mouse And Human Oocytes

Small, EarlyView.
Using Atomic Force Microscopy, the link between oocyte mechanical properties and actin cortex organization is investigated. In mouse oocytes, a thin actin cortex results in stiffer oocytes, while a thicker cortex leads to softer ones. Maternal age affects oocyte mechanics by altering cortex structure.
Rose Bulteau, Lucie Barbier, Guillaume Lamour, Yassir Lemseffer, Marie‐Hélène Verlhac, Nicolas Tessandier, Elsa Labrune, Martin Lenz, Marie‐Emilie Terret, Clément Campillo   +9 more
wiley   +1 more source

Mavacamten Cardiac Myosin Inhibitor: Clinical Applications and Future Perspectives. [PDF]

Cureus
Ramadan MM, Al-Najjar RA, Abady RS, Obaid HA, Mostafa YA, Al-Obeid MT, Elmahal M.   +6 more
europepmc   +1 more source

Near‐Infrared Fluorescent Single‐Walled Carbon Nanotubes for Biosensing

Small, EarlyView.
Near‐infrared fluorescent single‐walled carbon nanotubes (SWCNTs) stand out as versatile biosensors due to their spectral overlap with the biological transparency window, surface‐sensitive fluorescence emission, and chemical modularity. This review offers a concise guide to understanding the photophysics of SWCNTs, various functionalization strategies,
Srestha Basu, Gili Bisker
wiley   +1 more source

The Contractile Function of Ventricular Cardiomyocytes Is More Sensitive to Acute 17β-Estradiol Treatment Compared to Atrial Cardiomyocytes. [PDF]

Cells
Myachina TA, Butova XA, Simonova RA, Volzhaninov DA, Kochurova AM, Kopylova GV, Shchepkin DV, Khokhlova AD.   +7 more
europepmc   +1 more source

Treponema pallidum Protein Tp0136 Induces Spheroidization of Vascular Endothelial Cells, Resulting in Widened Intercellular Junctions and Enhanced Vascular Permeability

Small Science, EarlyView.
Treponema pallidum protein Tp0136 enhances vascular permeability by upregulating CSRP1, which induces MYO10 exon 19 skipping, reducing MYO10 expression and triggering endothelial spheroidization. This study reveals a novel RNA splicing‐mediated dissemination mechanism, proposing CSRP1/MYO10 as therapeutic targets to limit bacterial dissemination in ...
Yu Lin, Xi Luo, Xu Shen, Xiao‐Lin Fu, Li‐Rong Lin, Tian‐Ci Yang   +5 more
wiley   +1 more source

Autonomous Changes in Polymer Materials Driven by Chemical Fuels

ChemSystemsChem, EarlyView.
Inspired by out‐of‐equilibrium reaction networks in biochemical systems, chemical fuel reactions have been developed that impart time‐dependent properties to polymer materials. This review describes recent advances in the development of materials exhibiting transient changes in phase, mechanical properties, swelling, self‐healing, and self‐assembly ...
Chamoni W. H. Rajawasam, Dominik Konkolewicz, C. Scott Hartley   +2 more
wiley   +1 more source

Plasma POSTN Derived From Bile Proteome Is a Promising Biomarker for Cholangiocarcinoma With Efficacy Comparable and Complementary to CA19.9

United European Gastroenterology Journal, EarlyView.
ABSTRACT Background Cholangiocarcinoma presents a global health challenge due to its increasing incidence and poor prognosis, primarily resulting from delayed diagnosis. There is an urgent need for a reliable biomarker to enhance early detection. Materials and Methods Patients with cholangiocarcinoma were enrolled into three cohorts: a discovery set (n 
Lichieh Julie Chu, Chia‐Jung Tsai, Chun‐Chun Chien, Yung‐Chin Hsiao, Jau‐Song Yu, Jun‐Yi Tsai, Ta‐Sen Yeh   +6 more
wiley   +1 more source

Site-specific quantification of the in vivo UFMylome reveals myosin modification in ALS. [PDF]

Cell Rep Methods
Blazev R, Zee BM, Peckham H, Ng YK, Lewis CTA, Zhang C, McNamara JW, Goodman CA, Gregorevic P, Ochala J, Steyn FJ, Ngo ST, Stokes MP, Parker BL.   +13 more
europepmc   +1 more source

Effect of NF‐κB on Myosin Heavy Chain Content and Muscle Atrophy After Laryngeal Muscle Denervation

World Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.
ABSTRACT Objective To investigate the role of NF‐κB in regulating myosin heavy chain (MyHC) content and muscle atrophy following laryngeal muscle denervation. Methods Rats were divided into five groups: (1) recurrent laryngeal nerve injury (RLNI), (2) RLNI with NF‐κB inhibition, (3) sham operation, (4) sham operation with injection, and (5) blank ...
Jing‐Jing Yang, Rong Hu, Hai‐Zhou Wang, Xue‐Yan Li, Wen Xu   +4 more
wiley   +1 more source