Nanosurfer assay dissects β-cardiac myosin and cardiac myosin-binding protein C interactions. [PDF]
Touma AM+8 more
europepmc +1 more source
Quantification of myosin distribution predicts global morphogenetic flow in the fly embryo [PDF]
During embryogenesis tissue layers continuously rearrange and fold into specific shapes. Developmental biology identified patterns of gene expression and cytoskeletal regulation underlying local tissue dynamics, but how actions of multiple domains of distinct cell types coordinate to remodel tissues at the organ scale remains unclear.
arxiv
Proton Nuclear‐Magnetic‐Resonance Spectroscopy of Myosin Subfragment 1 Isoenzymes [PDF]
H. Paul PRINCE+7 more
openalex +1 more source
Hypertrophic Cardiomyopathy Mutations of Troponin Reveal Details of Striated Muscle Regulation. [PDF]
Chalovich JM, Zhu L, Johnson D.
europepmc +1 more source
Structural Change of Myosin Motor Domain and Nucleotide Dissociation [PDF]
We investigated the structural relaxation of myosin motor domain from the pre-power stroke state to the near-rigor state using molecular dynamics simulation of a coarse-grained protein model. To describe the structural change, we propose a "dual Go-model," a variant of the Go-like model that has two reference structures.
arxiv
On-grid and in-flow mixing for time-resolved cryo-EM. [PDF]
Klebl DP, White HD, Sobott F, Muench SP.
europepmc +1 more source
Association of microinjected myosin and its subfragments with myofibrils in living muscle cells. [PDF]
Cage S. Johnson+2 more
openalex +1 more source
Synthetic thick filaments: A new avenue for better understanding the myosin super-relaxed state in healthy, diseased, and mavacamten-treated cardiac systems. [PDF]
Gollapudi SK, Yu M, Gan QF, Nag S.
europepmc +1 more source
High-Speed Optical Traps Address Dynamics of Processive and Non-Processive Molecular Motors. [PDF]
Gardini L+5 more
europepmc +1 more source