Results 191 to 200 of about 15,479 (238)
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Current Opinion in Neurology, 1999
Sporadic inclusion body myositis is a severely disabling muscle disease that mainly affects elderly individuals. The typical distribution of muscle weakness, poor response to immunosuppressive treatment, pathological accumulation of various proteins in vacuolated muscle fibres, inflammatory reaction and mitochondrial changes have all been subjects of ...
A, Oldfors, C, Lindberg
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Sporadic inclusion body myositis is a severely disabling muscle disease that mainly affects elderly individuals. The typical distribution of muscle weakness, poor response to immunosuppressive treatment, pathological accumulation of various proteins in vacuolated muscle fibres, inflammatory reaction and mitochondrial changes have all been subjects of ...
A, Oldfors, C, Lindberg
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Continuum, 2022
This article highlights the clinical and diagnostic features of inclusion body myositis (IBM) and provides recent insights into the pathomechanisms and therapeutic strategies of the disease.IBM is an often-misdiagnosed myopathy subtype. Due to the insidious onset and slow progression of muscle weakness, it can often be dismissed as a sign of aging as ...
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This article highlights the clinical and diagnostic features of inclusion body myositis (IBM) and provides recent insights into the pathomechanisms and therapeutic strategies of the disease.IBM is an often-misdiagnosed myopathy subtype. Due to the insidious onset and slow progression of muscle weakness, it can often be dismissed as a sign of aging as ...
openaire +2 more sources
Neurology, 2006
Sporadic inclusion-body myositis (s-IBM) describes patients with chronic myositis whose biopsy specimens have, in addition to lymphocytic inflammation, abnormal muscle fibers containing characteristic filamentous inclusions in the cytoplasm and nuclei.
Valerie Askanas +2 more
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Sporadic inclusion-body myositis (s-IBM) describes patients with chronic myositis whose biopsy specimens have, in addition to lymphocytic inflammation, abnormal muscle fibers containing characteristic filamentous inclusions in the cytoplasm and nuclei.
Valerie Askanas +2 more
+4 more sources
Rheumatic Disease Clinics of North America, 1994
IBM remains a poorly understood form of idiopathic inflammatory myopathy, although great progress in the areas of clinical recognition and pathophysiology have been made recently. The question of whether therapy can favorably influence short- and/or long-term outcome is still unanswered.
L H, Calabrese, S M, Chou
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IBM remains a poorly understood form of idiopathic inflammatory myopathy, although great progress in the areas of clinical recognition and pathophysiology have been made recently. The question of whether therapy can favorably influence short- and/or long-term outcome is still unanswered.
L H, Calabrese, S M, Chou
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Current Treatment Options in Neurology, 2000
Inclusion body myositis (IBM) is usually refractory to immunosuppressive therapy; however, a few reports suggest that a minority of patients with IBM may have a partial, transient response or that therapy may slow progression. Therefore, although we generally discourage the use of immunosuppressive therapy for IBM, if the patient is willing to accept ...
, Barohn, , Amato
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Inclusion body myositis (IBM) is usually refractory to immunosuppressive therapy; however, a few reports suggest that a minority of patients with IBM may have a partial, transient response or that therapy may slow progression. Therefore, although we generally discourage the use of immunosuppressive therapy for IBM, if the patient is willing to accept ...
, Barohn, , Amato
openaire +2 more sources