Results 51 to 60 of about 9,601 (224)

Diagnostic Value of Muscle [11C] PIB-PET in Inclusion Body Myositis

Frontiers in Neurology, 2020
Background: The accumulation of multiple-protein aggregates within muscle fibers is a pathological hallmark of sporadic inclusion body myositis (s-IBM) with the presence of inclusion bodies. Amyloid-beta is one of the accumulated proteins in s-IBM.
Yu-ichi Noto, Masaki Kondo, Yukiko Tsuji, Shigenori Matsushima, Toshiki Mizuno, Takahiko Tokuda, Masanori Nakagawa   +6 more
doaj   +1 more source

Integrating One Health to Mitigate the Emergence and Spread of Antimicrobial Resistance in Livestock and Aquaculture

Animal Research and One Health, EarlyView.
Antimicrobial resistance (AMR) is an escalating global threat driven by antimicrobial use in aquaculture and livestock. Resistant pathogens and genes can spread across humans, animals, and the environment through interconnected ecosystems. Using a One Health approach, this review emphasizes antimicrobial stewardship, regulatory strengthening, enhanced ...
Mir Mohammad Ali, Delower Hossain, Ridwan Olamilekan Adesola, Anum Hanif, Shamsaldeen Ibrahim Saeed, Muhammad Abdul Mannan, Anoar Jamai Masroure, Kazi Estieque Alam, Md Kamal Hossain, Sabiha Zarin Tasnim Bristi, Md Jisan Ahmed   +10 more
wiley   +1 more source

Inclusion body myositis: evolving concepts. [PDF]

, 2022
PURPOSE OF REVIEW: To discuss recent developments in our understanding of epidemiology, diagnostics, biomarkers, pathology, pathogenesis, outcome measures, and therapeutics in inclusion body myositis (IBM).
Mozaffar, Tahseen, Perez-Rosendahl, Mari
core   +1 more source

A Case of Flaccid Quadriparesis

Indian Journal of Medical Specialities, 2019
Inclusion body myositis (IBM) is the most common inflammatory myopathy above the age of 50 years and three times more common in males than females. It presents as a distal more than proximal myopathy and has an indolent progressive course.
Kashish Gupta, Subhash Kumar, Narendra Bishnoi, Mayank Gupta, Sunil Kumar Mahavar, Raman Sharma   +5 more
doaj   +1 more source

Investigating the Role of Type I Interferon Signaling on Muscle Disease Using Mouse Models

Arthritis &Rheumatology, EarlyView.
Objective Dysregulated type I interferon (IFN) signaling contributes to autoimmune myositis pathogenesis. We investigated the therapeutic effects of JAK inhibitors in two mouse models. We also examined how type I IFNs affect muscle vasculature. Methods Myositis was induced in major histocompatibility complex class I double transgenic ([TRE‐H‐2Kb (H ...
Rita Spathis, Sabrina Narvesen, Deeva Robles Kuriplach, Karen Huang, Teja Sundar, Elizabeth Bagley, Joanna Parkes, Xinyu Jia, Nandhana Sudhan, Alfredo Guzman, Kanneboyina Nagaraju, Melissa Morales   +11 more
wiley   +1 more source

Integrated Multi-Omics Analysis for Inferring Molecular Players in Inclusion Body Myositis

Antioxidants, 2023
Inclusion body myositis (IBM) is an acquired inflammatory myopathy affecting proximal and distal muscles that leads to weakness in patients over 50.
Judith Cantó-Santos, Laura Valls-Roca, Ester Tobías, Clara Oliva, Francesc Josep García-García, Mariona Guitart-Mampel, Félix Andújar-Sánchez, Anna Esteve-Codina, Beatriz Martín-Mur, Joan Padrosa, Raquel Aránega, Pedro J. Moreno-Lozano, José César Milisenda, Rafael Artuch, Josep M. Grau-Junyent, Glòria Garrabou   +15 more
doaj   +1 more source

Treatment for inclusion body myositis

Cochrane Database of Systematic Reviews, 2015
Inclusion body myositis (IBM) is a late-onset inflammatory muscle disease (myopathy) associated with progressive proximal and distal limb muscle atrophy and weakness. Treatment options have attempted to target inflammatory and atrophic features of this condition (for example with immunosuppressive and immunomodulating drugs, anabolic steroids, and ...
Rose, Michael R., Jones, Katherine, Leong, Kevin, Walter, Maggie C., Miller, James, Dalakas, Marinos, Brassington, Ruth, Griggs, Robert   +7 more
openaire   +5 more sources

Inclusion body myositis. [PDF]

Journal of Neurology, Neurosurgery & Psychiatry, 1996
Since the early description of cases of inflammatory myopathy with unusual filamentous inclusions in muscle fibres inclusion body myotis has come to be recognised as a major form of idiopathic inflammatory with distinctive clinical and pathological features which accounts for up to a third of patients with inflammatory myopathy see in a neuromuscular ...
Garlepp, M.J., Mastaglia, F.L.
openaire   +2 more sources

Improved Detection of Myositis‐Specific Autoantibodies Using Luciferase Immunoprecipitation Systems Assay: Comparison With Line Blot and Conventional Immunoprecipitation

Arthritis &Rheumatology, EarlyView.
Objective Myositis‐specific autoantibodies guide the diagnosis and classification of idiopathic inflammatory myopathies, but current immunoassays vary in accuracy, particularly for autoantibodies associated with interstitial lung disease. To compare the performance of the luciferase immunoprecipitation systems (LIPS) assay with line blot and ...
Peter D. Burbelo, Iago Pinal‐Fernandez, Maria Casal‐Dominguez, Xin Tian, Shijinqiu Gao, Neha Gupta, Eric W. Robbins, John A. Chiorini, Christopher A. Mecoli, Lisa Christopher‐Stine, Livia Casciola‐Rosen, Andrew L. Mammen, Sonye K. Danoff, Anthony F. Suffredini, Julio A. Huapaya   +14 more
wiley   +1 more source

Electromyography varies by stage in inclusion body myositis

Frontiers in Neurology
IntroductionInclusion body myositis (IBM) is a chronic inflammatory muscle disease that is characterized by mixed myogenic and neurogenic electromyography (EMG) findings.
Tomoo Mano, Tomoo Mano, Naohiko Iguchi, Nobuyuki Eura, Naoki Iwasa, Nanami Yamada, Hirosei Horikawa, Kazuma Sugie   +7 more
doaj   +1 more source