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Inclusion Body Myositis [PDF]

, 2019
Last Update: April 23, 2019. Access free multiple choice questions on this topicInclusion body myositis (IBM) is the most common subtype of autoimmune myopathy in patients older than the age of 50 years. Several diagnostic criteria have been proposed for
Musa, Rina, Panginikkod, Sreelakshmi
openaire   +3 more sources

Integrated Clinical and Proteomic Profiling of CD19 Chimeric Antigen Receptor T Cell Therapy in Progressive Systemic Sclerosis

Arthritis &Rheumatology, EarlyView.
Objective To characterize the clinical, immunologic, and proteomic changes associated with CD19 chimeric antigen receptor T cell therapy in patients with progressive systemic sclerosis (SSc). Methods Patients with progressive SSc received CD19 chimeric antigen receptor (CAR)‐T cell therapy and were observed longitudinally for safety, clinical efficacy,
Chenhan Jia, Wanyi Lin, Zhangyi Zhao, Fenglin Wu, Chaoyu Gu, Yuankai Sun, Zhe Ding, Chang Wei, Xinyu Li, Cuiwei Xie, Peng Xia, Zhen Xia, Xuesong Liu, Shaoying Yang, Chunyan Zhang, Hanlin Yin, Liangjing Lu   +16 more
wiley   +1 more source

Treatment‐Related Adverse Events and Health‐Related Quality of Life Associated With Immune Checkpoint Inhibitor Treatment for Mucosal Head and Neck Squamous Cell Carcinoma: A Scoping Review

Head &Neck, EarlyView.
ABSTRACT Background Supportive care needs of patients receiving immune checkpoint inhibitors (ICIs) for head and neck squamous cell carcinoma (HNSCC) are ill‐defined. Hence, known treatment‐related adverse events (TRAEs) and health‐related quality of life (HRQoL) associated with ICI treatment for HNSCC were examined to inform future supportive care ...
N. D. O'Donnell, E. C. Ward, L. R. Wishart, R. Perera, C. Barrett, K. A. Edmiston, E. Mitchell, A. Pigott, R. Pitt, K. Russell, B. A. Chan, R. Ladwa   +11 more
wiley   +1 more source

Psychosocial Determinants of Pain in Muscle Biopsy

Muscle &Nerve, EarlyView.
ABSTRACT Introduction/Aims Open muscle biopsy (OMB) is a key diagnostic tool for neuromuscular diseases, though patients often worry about risks and discomfort. This study aimed to assess pain during and after OMB, factors influencing pain perception, and adverse events.
Beatrice Labella, Emmanuelle Lacene, Maud Beuvin, Anaïs Chanut, Angeline Madelaine, Favienne Levy‐Borsato, Guy Brochier, Clémence Labasse, Guillaume Bassez, Danielle Seilhean, Sarah Leonard‐Louis, Teresinha Evangelista   +11 more
wiley   +1 more source

Aberrant Expression of High Mobility Group Box Protein 1 in the Idiopathic Inflammatory Myopathies

Frontiers in Cell and Developmental Biology, 2020
IntroductionHigh Mobility Group Box Protein 1 (HMGB1) is a DNA-binding protein that exerts inflammatory or pro-repair effects upon translocation from the nucleus.
Jessica Day, Jessica Day, Jessica Day, Sophia Otto, Sophia Otto, Kathy Cash, Preethi Eldi, Preethi Eldi, Pravin Hissaria, Pravin Hissaria, Susanna Proudman, Susanna Proudman, Vidya Limaye, Vidya Limaye, John D. Hayball, John D. Hayball, John D. Hayball   +16 more
doaj   +1 more source

Balloon Dilation in Sporadic Inclusion Body Myositis Patients with Dysphagia

Clinical Medicine Insights: Case Reports, 2013
Here, we describe balloon catheter dilation at the upper esophageal sphincter (UES) in three sporadic inclusion body myositis (s-IBM) patients with dysphagia.
Ken-ya Murata, Ken Kouda, Fumihiro Tajima, Tomoyoshi Kondo   +3 more
doaj   +2 more sources

Multicenter questionnaire survey for sporadic inclusion body myositis in Japan

Orphanet Journal of Rare Diseases, 2016
Background Sporadic inclusion body myositis (sIBM) is the most prevalent acquired muscle disease in the elderly. sIBM is an intractable and progressive disease of unknown cause and without effective treatment.
Naoki Suzuki, Madoka Mori-Yoshimura, Satoshi Yamashita, Satoshi Nakano, Ken-ya Murata, Yukie Inamori, Naoko Matsui, En Kimura, Hirofumi Kusaka, Tomoyoshi Kondo, Itsuro Higuchi, Ryuji Kaji, Maki Tateyama, Rumiko Izumi, Hiroya Ono, Masaaki Kato, Hitoshi Warita, Toshiaki Takahashi, Ichizo Nishino, Masashi Aoki   +19 more
doaj   +1 more source

Myasthenia Gravis and Thymoma

Muscle &Nerve, EarlyView.
ABSTRACT Thymoma is the most common tumor of the anterior mediastinum. Approximately 20%–30% of patients with a thymoma develop myasthenia gravis (MG), and an additional one third may possess positive acetylcholine receptor (AChR) antibodies without MG.
Benjamin Claytor, Lukas Delasos, Daniel P. Raymond, Erik Seroogy, Jason Lempel, Yuebing Li   +5 more
wiley   +1 more source

Role of noninvasive ventilation in perioperative patients with neuromuscular disease: a clinical case

Brazilian Journal of Anesthesiology, 2016
The inclusion body myositis is an inflammatory myopathy that leads to chronic muscle inflammation associated with muscle weakness. It is characterized by a restrictive ventilatory syndrome requiring ventilatory support under non-invasive ventilation. The
Ana Marinho, Mario José Guimarães, Neusa Cristina Ribeiro Lages, Carlos Correia   +3 more
doaj   +3 more sources

A case of canine urothelial carcinoma of the urinary bladder with skull and skeletal metastases

Australian Veterinary Journal, EarlyView.
Canine urinary bladder neoplasia is uncommon, representing less than 1% of canine neoplasms. Amongst cases of urinary bladder neoplasia in dogs, primary urothelial carcinoma is the most frequent. Urothelial carcinomas are malignant invasive tumours which tend to be slow growing and metastasise late.
A Teh, T Sima, E Shinozaki, R Malik
wiley   +1 more source