Results 1 to 10 of about 94 (65)

Sporadic Inclusion Body Myositis: An Acquired Mitochondrial Disease with Extras

Biomolecules, 2019
The sporadic form of inclusion body myositis (IBM) is the most common late-onset myopathy. Its complex pathogenesis includes degenerative, inflammatory and mitochondrial aspects.
Boel De Paepe
doaj   +3 more sources

Balloon Dilation in Sporadic Inclusion Body Myositis Patients with Dysphagia

Clinical Medicine Insights: Case Reports, 2013
Here, we describe balloon catheter dilation at the upper esophageal sphincter (UES) in three sporadic inclusion body myositis (s-IBM) patients with dysphagia.
Ken-ya Murata, Ken Kouda, Fumihiro Tajima, Tomoyoshi Kondo   +3 more
doaj   +4 more sources

Myo-Inositol Transporter SLC5A3 Associates with Degenerative Changes and Inflammation in Sporadic Inclusion Body Myositis

Biomolecules, 2020
Myo-inositol exerts many cellular functions, which include osmo-protection, membrane functioning, and secondary messaging. Its Na+/myo-inositol co-transporter SLC5A3 is expressed in muscle tissue and further accumulates in myositis.
Boel De Paepe, Caroline Merckx, Jana Jarošová, Miryam Cannizzaro, Jan L. De Bleecker   +4 more
doaj   +3 more sources

Anti-cN1A Antibodies Are Associated with More Severe Dysphagia in Sporadic Inclusion Body Myositis

Cells, 2021
In recent years, an autoantibody directed against the 5′-citosolic nucleotidase1A (cN1A) was identified in the sera of sporadic inclusion body myositis (s-IBM) patients with widely variable sensitivity (33%–76%) and specificity (87%–100%).
Matteo Lucchini, Lorenzo Maggi, Elena Pegoraro, Massimiliano Filosto, Carmelo Rodolico, Giovanni Antonini, Matteo Garibaldi, Maria Lucia Valentino, Gabriele Siciliano, Giorgio Tasca, Valeria De Arcangelis, Chiara De Fino, Massimiliano Mirabella   +12 more
doaj   +3 more sources

Increasing daily duration of rehabilitation for inpatients with sporadic inclusion body myositis may contribute to improvement in activities of daily living: A nationwide database cohort study

Journal of Rehabilitation Medicine, 2023
Objective: To analyse the association between the daily duration of rehabilitation for inpatients with sporadic inclusion body myositis and improvement in activities of daily living, using a Japanese nationwide inpatient administrative claims database ...
Takuaki Tani, Shinobu Imai, Kiyohide Fushimi   +2 more
doaj   +1 more source

A Rare Case of Sporadic Inclusion Body Myositis (s-IBM) [PDF]

Journal of Clinical and Diagnostic Research, 2016
Sporadic inclusion body myositis (s-IBM) is an acquired inflammatory myopathy. Clinical presentation is variable. The usual presentation is progressive weakness and atrophy of the arms and leg muscles, especially of the quadriceps femoris which is ...
Sourya Acharya, Samarth Shukla, Pritum Kitey, Shameem Khan, SN Mahajan   +4 more
doaj   +1 more source

Sporadic inclusion body myositis in the rheumatology clinic

Indian Journal of Rheumatology, 2020
Sporadic inclusion body myositis (sIBM) is a progressive and insidious skeletal muscle disorder characterized classically by the quadriceps, wrist, and finger flexor weakness.
Fernando Henrique Carlos de Souza, Gustavo Luiz Behrens Pinto, Jean Marcos de Souza, Pablo Arturo Olivo Pallo, Leonardo Santos Hoff, Samuel Katsuyuki Shinjo   +5 more
doaj   +1 more source

Revisiting the Role of GSK3, A Modulator of Innate Immunity, in Idiopathic Inclusion Body Myositis

Cells, 2021
Idiopathic or sporadic inclusion body myositis (IBM) is the leading age-related (onset >50 years of age) autoimmune muscular pathology, resulting in significant debilitation in affected individuals. Once viewed as primarily a degenerative disorder, it is
Manuela Piazzi, Alberto Bavelloni, Vittoria Cenni, Irene Faenza, William L. Blalock   +4 more
doaj   +1 more source

Metabolome and transcriptome analysis on muscle of sporadic inclusion body myositis

Annals of Clinical and Translational Neurology, 2022
Objective Sporadic inclusion body myositis (sIBM) is the most common acquired myopathy in patients older than 50 years of age. sIBM is hardly responds to any immunosuppressing theraphies, and its pathophysiology remains elusive.
Ayuka Murakami, Seiya Noda, Tomoyuki Kazuta, Satoko Hirano, Seigo Kimura, Hirotaka Nakanishi, Koji Matsuo, Koyo Tsujikawa, Madoka Iida, Haruki Koike, Kazuma Sakamoto, Yuichiro Hara, Satoshi Kuru, Kenji Kadomatsu, Teppei Shimamura, Tomoo Ogi, Masahisa Katsuno   +16 more
doaj   +1 more source

Tendon Transfers to Improve Grip and Pinch in Patients with Sporadic Inclusion Body Myositis

Plastic and Reconstructive Surgery, Global Open, 2023
Background:. Sporadic inclusion body myositis (sIBM) is a rare and slowly progressive skeletal muscle disease that can cause hand dysfunction, which is a major source of disability.
Catherine Hua, BA, Salman Bhai, MD, Jonathan Cheng, MD, Jose Hinojosa, MS, Lynn Wilson, BS, Manuel Lubinus, MBA, PhD, Abhiram R. Bhashyam, MD, PhD   +6 more
doaj   +1 more source