Results 31 to 40 of about 2,106 (149)

Macroautophagy as a Pathomechanism in Sporadic Inclusion Body Myositis [PDF]

open access: yesAutophagy, 2007
Skeletal muscle fibers show a high level of constitutive and starvation-induced macroautophagy. Sporadic Inclusion Body Myositis (sIBM) is the most common acquired skeletal muscle disease in patients above the age of 50 years and is characterized by inflammation and intracellular accumulation of aggregate-prone proteins such as amyloid precursor ...
Lunemann, Jan D.   +3 more
openaire   +3 more sources

Update on sporadic inclusion body myositis [PDF]

open access: yesBrain, 2011
Sporadic inclusion body myositis (IBM) is the most frequent acquired myopathy seen in adults aged over 50 years. Despite the presence of conspicuous inflammatory infiltrates, sporadic IBM is essentially resistant to immunosuppressive treatment and carries an ominous prognosis.
openaire   +2 more sources

Inclusion body myositis – pathomechanism and lessons from genetics

open access: yesOpen Medicine, 2015
Inclusion body myositis is a rare, late-onset myopathy. Both inflammatory and myodegenerative features play an important role in their pathogenesis.
Murnyák Balázs   +8 more
doaj   +1 more source

Combination of sporadic inclusion body myositis and primary Sjögren’s syndrome: clinical case and review of literature

open access: yesСовременная ревматология, 2023
The article presents a review of the literature and a clinical observation of a patient with long-term anamnesis of primary Sjögren's syndrome (SS) in combination with sporadic inclusion body myositis (sIBM).
Yu. I. Khvan   +1 more
doaj   +1 more source

Evolving classification and role of muscle biopsy in diagnosis of inflammatory myopathies

open access: yesIndian Journal of Pathology and Microbiology, 2022
Idiopathic inflammatory myopathy (IIM) is a broad term that includes dermatomyositis, polymyositis, overlap myositis, sporadic inclusion body myositis, and immune-mediated necrotizing myopathy.
Meenakshi Swain, Megha Uppin
doaj   +1 more source

OUTPATIENT PHYSICAL THERAPY EVALUATION AND TREATMENT OF A PATIENT DIAGNOSED WITH SPORADIC INCLUSION BODY MYOSITIS: A CASE STUDY

open access: yesInternational Journal of Physiotherapy, 2017
Background: Sporadic inclusion body myositis is an autoimmune and degenerative disorder of skeletal muscle that affects people at random. It most commonly begins as progressive weakness and atrophy of lower extremity musculature, beginning with the ...
Tyler Harrigfeld, Trent Jackman
doaj   +1 more source

Cardiac Involvement in Sporadic Inclusion-Body Myositis [PDF]

open access: yesCirculation, 2010
A 36-year-old man came to the emergency department with acute onset of exertional chest pain. He had had no recent infections, and no cardiovascular risk factors were present. However, the patient had used a wheelchair since his mid-20s because of sporadic inclusion-body myositis, as established by muscle biopsy.
Wolfgang, Utz   +4 more
openaire   +2 more sources

Sporadic inclusion body myositis: overreliance on histology may lead to misdiagnosis [PDF]

open access: yesFolia Medica
We describe a 57-year-old man who had initial isolated weakness in the deep finger flexors of his non-dominant hand, followed by quadriceps weakness and wasting a year later.
Behidzhe Sadarzanska-Terzieva   +2 more
doaj   +3 more sources

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